| RNA polymerase III transcription factor TFIIIC2 is overexpressed in ovarian tumors AG Winter, G Sourvinos, SJ Allison, K Tosh, PH Scott, DA Spandidos, ... Proceedings of the National Academy of Sciences 97 (23), 12619-12624, 2000 | 179 | 2000 |
| SIRT3 is pro-apoptotic and participates in distinct basal apoptotic pathways SJ Allison, JO Milner Cell cycle 6 (21), 2669-2677, 2007 | 173 | 2007 |
| JNK2-dependent regulation of SIRT1 protein stability J Ford, S Ahmed, S Allison, M Jiang, J Milner Cell cycle 7 (19), 3091-3097, 2008 | 159 | 2008 |
| Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD (H)-dependent and (ii) p53-independent pathways SJ Allison, JRP Knight, C Granchi, R Rani, F Minutolo, J Milner, ... Oncogenesis 3 (5), e102-e102, 2014 | 131 | 2014 |
| Development and characterization of a microfluidic model of the tumour microenvironment JM Ayuso, M Virumbrales-Muņoz, A Lacueva, PM Lanuza, ... Scientific reports 6 (1), 36086, 2016 | 125 | 2016 |
| CK2 forms a stable complex with TFIIIB and activates RNA polymerase III transcription in human cells IM Johnston, SJ Allison, JP Morton, L Schramm, PH Scott, RJ White Molecular and cellular biology 22 (11), 3757-3768, 2002 | 104 | 2002 |
| Retinoblastoma protein disrupts interactions required for RNA polymerase III transcription JE Sutcliffe, TRP Brown, SJ Allison, PH Scott, RJ White Molecular and cellular biology, 2000 | 96 | 2000 |
| RNA polymerase III transcription factor IIIB is a target for repression by pocket proteins p107 and p130 JE Sutcliffe, CA Cairns, A McLees, SJ Allison, K Tosh, RJ White Molecular and cellular biology, 1999 | 82 | 1999 |
| Hypoxia-sensitive metal β-ketoiminato complexes showing induced single-strand DNA breaks and cancer cell death by apoptosis RM Lord, AJ Hebden, CM Pask, IR Henderson, SJ Allison, SL Shepherd, ... Journal of Medicinal Chemistry 58 (12), 4940-4953, 2015 | 68 | 2015 |
| KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice ES Polson, VB Kuchler, C Abbosh, EM Ross, RK Mathew, HA Beard, ... Science translational medicine 10 (454), eaar2718, 2018 | 67 | 2018 |
| Remodelling chromatin on a global scale: a novel protective function of p53 SJ Allison, J Milner Carcinogenesis 25 (9), 1551-1557, 2004 | 67 | 2004 |
| Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands SJ Allison, M Sadiq, E Baronou, PA Cooper, C Dunnill, NT Georgopoulos, ... Cancer letters 403, 98-107, 2017 | 63 | 2017 |
| Oncogenic viral protein HPV E7 up-regulates the SIRT1 longevity protein in human cervical cancer cells SJ Allison, M Jiang, J Milner Aging 1 (3), 316, 2009 | 60 | 2009 |
| Polysialic acid sustains cancer cell survival and migratory capacity in a hypoxic environment SM Elkashef, SJ Allison, M Sadiq, HA Basheer, G Ribeiro Morais, ... Scientific reports 6 (1), 33026, 2016 | 57 | 2016 |
| SIRT1 undergoes alternative splicing in a novel auto-regulatory loop with p53 CJ Lynch, ZH Shah, SJ Allison, SU Ahmed, J Ford, LJ Warnock, H Li, ... PloS one 5 (10), e13502, 2010 | 57 | 2010 |
| Loss of p53 has site-specific effects on histone H3 modification, including serine 10 phosphorylation important for maintenance of ploidy SJ Allison, J Milner Cancer research 63 (20), 6674-6679, 2003 | 56 | 2003 |
| Anticancer metallohelices: nanomolar potency and high selectivity RA Kaner, SJ Allison, AD Faulkner, RM Phillips, DI Roper, SL Shepherd, ... Chemical Science 7 (2), 951-958, 2016 | 50 | 2016 |
| Ruthenium‐containing linear helicates and mesocates with tuneable p53‐selective cytotoxicity in colorectal cancer cells SJ Allison, D Cooke, FS Davidson, PIP Elliott, RA Faulkner, HBS Griffiths, ... Angewandte Chemie International Edition 57 (31), 9799-9804, 2018 | 43 | 2018 |
| Hypoxia modulates the activity of a series of clinically approved tyrosine kinase inhibitors M Ahmadi, Z Ahmadihosseini, SJ Allison, S Begum, K Rockley, M Sadiq, ... British journal of pharmacology 171 (1), 224-236, 2014 | 42 | 2014 |
| A deacetylase-deficient SIRT1 variant opposes full-length SIRT1 in regulating tumor suppressor p53 and governs expression of cancer-related genes ZH Shah, SU Ahmed, JR Ford, SJ Allison, JRP Knight, J Milner Molecular and cellular biology 32 (3), 704-716, 2012 | 40 | 2012 |
