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Roberta Bortolozzi
Roberta Bortolozzi
Università degli studi di Padova, Dipartimento salute della donna e del bambino
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Synthesis and antitumor activity of 1, 5-disubstituted 1, 2, 4-triazoles as cis-restricted combretastatin analogues
R Romagnoli, PG Baraldi, O Cruz-Lopez, C Lopez Cara, MD Carrion, ...
Journal of medicinal chemistry 53 (10), 4248-4258, 2010
1912010
Synthesis and evaluation of 1, 5-disubstituted tetrazoles as rigid analogues of combretastatin A-4 with potent antiproliferative and antitumor activity
R Romagnoli, PG Baraldi, MK Salvador, D Preti, M Aghazadeh Tabrizi, ...
Journal of medicinal chemistry 55 (1), 475-488, 2012
1792012
MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells
G Viola, R Bortolozzi, E Hamel, S Moro, P Brun, I Castagliuolo, MG Ferlin, ...
Biochemical pharmacology 83 (1), 16-26, 2012
1192012
Synthesis and Biological Evaluation of 2-(Alkoxycarbonyl)-3-Anilinobenzo[b]thiophenes and Thieno[2,3-b]pyridines as New Potent Anticancer Agents
R Romagnoli, PG Baraldi, M Kimatrai Salvador, D Preti, ...
Journal of medicinal chemistry 56 (6), 2606-2618, 2013
1092013
Convergent synthesis and biological evaluation of 2-amino-4-(3′, 4′, 5′-trimethoxyphenyl)-5-aryl thiazoles as microtubule targeting agents
R Romagnoli, PG Baraldi, A Brancale, A Ricci, E Hamel, R Bortolozzi, ...
Journal of medicinal chemistry 54 (14), 5144-5153, 2011
1072011
Synthesis and biological evaluation of 2-substituted-4-(3′, 4′, 5′-trimethoxyphenyl)-5-aryl thiazoles as anticancer agents
R Romagnoli, PG Baraldi, MK Salvador, ME Camacho, D Preti, MA Tabrizi, ...
Bioorganic & medicinal chemistry 20 (24), 7083-7094, 2012
772012
Recent advances in vascular disrupting agents in cancer therapy
E Porcù, R Bortolozzi, G Basso, G Viola
Future medicinal chemistry 6 (13), 1485-1498, 2014
692014
Discovery and optimization of a series of 2-aryl-4-amino-5-(3′, 4′, 5′-trimethoxybenzoyl) thiazoles as novel anticancer agents
R Romagnoli, PG Baraldi, MK Salvador, D Preti, M Aghazadeh Tabrizi, ...
Journal of Medicinal Chemistry 55 (11), 5433-5445, 2012
682012
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents
R Romagnoli, PG Baraldi, C Lopez-Cara, D Preti, M Aghazadeh Tabrizi, ...
Journal of medicinal chemistry 56 (22), 9296-9309, 2013
652013
Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors
SN Baytas, N Inceler, A Yılmaz, A Olgac, S Menevse, E Banoglu, E Hamel, ...
Bioorganic & medicinal chemistry 22 (12), 3096-3104, 2014
642014
Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin
R Romagnoli, PG Baraldi, MK Salvador, F Prencipe, C Lopez-Cara, ...
Journal of medicinal chemistry 58 (7), 3209-3222, 2015
612015
Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia
V Serafin, G Capuzzo, G Milani, SA Minuzzo, M Pinazza, R Bortolozzi, ...
Blood, The Journal of the American Society of Hematology 130 (25), 2750-2761, 2017
602017
9‐(4‐Dimethylaminophenyl)benzo[b]quinolizinium: A Near‐Infrared Fluorophore for the Multicolor Analysis of Proteins and Nucleic Acids in Living Cells
R Bortolozzi, H Ihmels, L Thomas, M Tian, G Viola
Chemistry–A European Journal 27 (19), 8736-8741, 2013
552013
Synthesis and biological evaluation of 2-(3′, 4′, 5′-trimethoxybenzoyl)-3-aryl/arylaminobenzo [b] thiophene derivatives as a novel class of antiproliferative agents
R Romagnoli, PG Baraldi, CL Cara, E Hamel, G Basso, R Bortolozzi, ...
European journal of medicinal chemistry 45 (12), 5781-5791, 2010
512010
Design, synthesis and biological evaluation of 3, 5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents
R Romagnoli, PG Baraldi, C Lopez-Cara, MK Salvador, D Preti, ...
Bioorganic & medicinal chemistry 22 (18), 5097-5109, 2014
452014
Selective ratiometric detection of H 2 O 2 in water and in living cells with boronobenzo [b] quinolizinium derivatives
R Bortolozzi, S von Gradowski, H Ihmels, K Schäfer, G Viola
Chemical communications 50 (60), 8242-8245, 2014
452014
Pyrrolo[2′,3′:3,4]cyclohepta[1,2-d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types
V Spano, R Rocca, M Barreca, D Giallombardo, A Montalbano, ...
Journal of medicinal chemistry 63 (20), 12023-12042, 2020
442020
Design, synthesis, and structure–activity relationships of azolylmethylpyrroloquinolines as nonsteroidal aromatase inhibitors
MG Ferlin, D Carta, R Bortolozzi, R Ghodsi, A Chimento, V Pezzi, S Moro, ...
Journal of Medicinal Chemistry 56 (19), 7536-7551, 2013
432013
TR-644 a novel potent tubulin binding agent induces impairment of endothelial cells function and inhibits angiogenesis
E Porcu, G Viola, R Bortolozzi, L Persano, S Mitola, R Ronca, M Presta, ...
Angiogenesis 16, 647-662, 2013
412013
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and …
R Romagnoli, F Prencipe, P Oliva, S Baraldi, PG Baraldi, ...
Journal of Medicinal Chemistry 62 (3), 1274-1290, 2019
392019
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