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Helene A Fachim
Helene A Fachim
Principle Scientist, PharmaKure
Verified email at manchester.ac.uk
Title
Cited by
Cited by
Year
Anticonvulsant profile of the alkaloids (+)-erythravine and (+)-11-α-hydroxy-erythravine isolated from the flowers of Erythrina mulungu Mart ex Benth (Leguminosae–Papilionaceae)
SA Faggion, AOS Cunha, HA Fachim, AS Gavin, WF dos Santos, ...
Epilepsy & Behavior 20 (3), 441-446, 2011
732011
Erysothrine, an alkaloid extracted from flowers of Erythrina mulungu Mart. ex Benth: evaluating its anticonvulsant and anxiolytic potential
DS Rosa, SA Faggion, AS Gavin, MA de Souza, HA Fachim, ...
Epilepsy & Behavior 23 (3), 205-212, 2012
662012
Cytokine profile in first-episode psychosis, unaffected siblings and community-based controls: the effects of familial liability and childhood maltreatment
F Corsi-Zuelli, CM Loureiro, R Shuhama, HA Fachim, PR Menezes, ...
Psychological medicine 50 (7), 1139-1147, 2020
602020
GRIN2B promoter methylation deficits in early-onset schizophrenia and its association with cognitive function
HA Fachim, CM Loureiro, F Corsi-Zuelli, R Shuhama, P Louzada-Junior, ...
Epigenomics 11 (4), 401-410, 2019
372019
Parvalbumin promoter hypermethylation in postmortem brain in schizophrenia
HA Fachim, U Srisawat, CF Dalton, GP Reynolds
Epigenomics 10 (5), 519-524, 2018
372018
Neurobiological activity of Parawixin 10, a novel anticonvulsant compound isolated from Parawixia bistriata spider venom (Araneidae: Araneae)
HA Fachim, AOS Cunha, AC Pereira, RO Beleboni, L Gobbo-Neto, ...
Epilepsy & Behavior 22 (2), 158-164, 2011
332011
Early-life stress effects on BDNF DNA methylation in first-episode psychosis and in rats reared in isolation
HA Fachim, F Corsi-Zuelli, CM Loureiro, S Iamjan, R Shuhama, S Joca, ...
Progress in Neuro-Psychopharmacology and Biological Psychiatry 108, 110188, 2021
272021
Low plasma concentrations of N-methyl-d-aspartate receptor subunits as a possible biomarker for psychosis
CM Loureiro, R Shuhama, HA Fachim, PR Menezes, CM Del-Ben, ...
Schizophrenia Research 202, 55-63, 2018
242018
Subchronic administration of phencyclidine produces hypermethylation in the parvalbumin gene promoter in rat brain
HA Fachim, U Srisawat, CF Dalton, MK Harte, S Marsh, JC Neill, ...
Epigenomics 8 (9), 1179-1183, 2016
222016
Prolonged periods of social isolation from weaning reduce the anti-inflammatory cytokine IL-10 in blood and brain
F Corsi-Zuelli, HA Fachim, CM Loureiro, R Shuhama, G Bertozi, SRL Joca, ...
Frontiers in neuroscience 12, 427182, 2019
212019
Does DNA methylation influence the effects of psychiatric drugs?
GP Reynolds, HA Fachim
Epigenomics 8 (3), 309-312, 2016
182016
Neurotransmissão glutamatérgica e plasticidade sináptica: aspectos moleculares, clínicos e filogenéticos
RN Ruggiero, LS Bueno-Júnior, JB de Ross, HA Fachim, ...
Medicina (Ribeirão Preto) 44 (2), 143-156, 2011
172011
Data independent acquisition mass spectrometry can identify circulating proteins that predict future weight loss with a diet and exercise programme
N Malipatil, HA Fachim, K Siddals, B Geary, G Wark, N Porter, S Anderson, ...
Journal of clinical medicine 8 (2), 141, 2019
152019
Increased DNA methylation in the parvalbumin gene promoter is associated with methamphetamine dependence
S Veerasakul, P Watiktinkorn, S Thanoi, CF Dalton, HA Fachim, ...
Pharmacogenomics 18 (14), 1317-1322, 2017
152017
The risk factors potentially influencing hospital admission in people with diabetes, following SARS-CoV-2 infection: a population-level analysis
AH Heald, DA Jenkins, R Williams, M Sperrin, H Fachim, RN Mudaliar, ...
Diabetes Therapy 13 (5), 1007-1021, 2022
142022
Androgen receptor-reduced sensitivity is associated with increased mortality and poorer glycaemia in men with type 2 diabetes mellitus: a prospective cohort study
AH Heald, M Livingston, H Fachim, M Lunt, RP Narayanan, K Siddals, ...
Cardiovascular endocrinology & metabolism 10 (1), 37-44, 2021
142021
Neuroprotective activity of parawixin 10, a compound isolated from Parawixia bistriata spider venom (Araneidae: Araneae) in rats undergoing intrahippocampal NMDA microinjection
HA Fachim, MR Mortari, L Gobbo-Netto, WF Dos Santos
Pharmacognosy magazine 11 (43), 579, 2015
142015
Differential expression of AMPA subunits induced by NMDA intrahippocampal injection in rats
HA Fachim, AC Pereira, MM Iyomasa-Pilon, MLNM Rosa
Frontiers in neuroscience 10, 170274, 2016
132016
Changes of BDNF exon IV DNA methylation are associated with methamphetamine dependence
S Iamjan, S Thanoi, P Watiktinkorn, H Fachim, CF Dalton, ...
Epigenomics 13 (12), 953-965, 2021
112021
Plasma amino acids profile in first-episode psychosis, unaffected siblings and community-based controls
CM Loureiro, DL da Roza, F Corsi-Zuelli, R Shuhama, HA Fachim, ...
Scientific reports 10 (1), 21423, 2020
92020
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