| Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes–associated variants TJ Nicolson, EA Bellomo, N Wijesekara, MK Loder, JM Baldwin, ... Diabetes 58 (9), 2070-2083, 2009 | 444 | 2009 |
| Roles of 5′-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis GA Rutter, G da Silva Xavier, I Leclerc Biochemical Journal 375 (1), 1-16, 2003 | 433 | 2003 |
| The cells of the islets of Langerhans G Da Silva Xavier Journal of clinical medicine 7 (3), 54, 2018 | 363 | 2018 |
| Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression G da Silva Xavier, I Leclerc, A Varadi, T Tsuboi, SK Moule, GA Rutter Biochemical Journal 371 (3), 761-774, 2003 | 321 | 2003 |
| miR-29a and miR-29b contribute to pancreatic β-cell-specific silencing of monocarboxylate transporter 1 (Mct1) TJ Pullen, G da Silva Xavier, G Kelsey, GA Rutter Molecular and cellular biology 31 (15), 3182-3194, 2011 | 311 | 2011 |
| Glutamine potently stimulates glucagon-like peptide-1 secretion from GLUTag cells F Reimann, L Williams, G da Silva Xavier, GA Rutter, FM Gribble Diabetologia 47, 1592-1601, 2004 | 297 | 2004 |
| TCF7L2 regulates late events in insulin secretion from pancreatic islet β-cells G da Silva Xavier, MK Loder, A McDonald, AI Tarasov, R Carzaniga, ... Diabetes 58 (4), 894-905, 2009 | 278 | 2009 |
| Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression G da Silva Xavier, I Leclerc, IP Salt, B Doiron, DG Hardie, A Kahn, ... Proceedings of the National Academy of Sciences 97 (8), 4023-4028, 2000 | 264 | 2000 |
| Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells T Tsuboi, G SILVA XAVIER, GG Holz, LS Jouaville, AP Thomas, GA Rutter Biochemical Journal 369 (2), 287-299, 2003 | 235 | 2003 |
| Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion I Leclerc, WW Woltersdorf, G da Silva Xavier, RL Rowe, SE Cross, ... American Journal of Physiology-Endocrinology and Metabolism 286 (6), E1023-E1031, 2004 | 212 | 2004 |
| Dynamic changes in cytosolic and mitochondrial ATP levels in pancreatic acinar cells SG Voronina, SL Barrow, AWM Simpson, OV Gerasimenko, ... Gastroenterology 138 (5), 1976-1987. e5, 2010 | 155 | 2010 |
| Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic β cells V Dominguez, C Raimondi, S Somanath, M Bugliani, MK Loder, ... Journal of Biological Chemistry 286 (6), 4216-4225, 2011 | 151 | 2011 |
| 5′-AMP-activated protein kinase controls insulin-containing secretory vesicle dynamics T Tsuboi, G da Silva Xavier, I Leclerc, GA Rutter Journal of Biological Chemistry 278 (52), 52042-52051, 2003 | 139 | 2003 |
| Glucose-stimulated preproinsulin gene expression and nucleartrans-location of pancreatic duodenum homeobox-1 require activation of phosphatidylinositol 3-kinase but not p38 … I Rafiq, G da Silva Xavier, S Hooper, GA Rutter Journal of Biological Chemistry 275 (21), 15977-15984, 2000 | 130 | 2000 |
| Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion JM Locke, G da Silva Xavier, HR Dawe, GA Rutter, LW Harries Diabetologia 57, 122-128, 2014 | 123 | 2014 |
| Abnormal glucose tolerance and insulin secretion in pancreas-specific Tcf7l2-null mice G da Silva Xavier, A Mondragon, G Sun, L Chen, JA McGinty, PM French, ... Diabetologia 55, 2667-2676, 2012 | 122 | 2012 |
| Selective disruption of Tcf7l2 in the pancreatic β cell impairs secretory function and lowers β cell mass RK Mitchell, A Mondragon, L Chen, JA Mcginty, PM French, J Ferrer, ... Human molecular genetics 24 (5), 1390-1399, 2015 | 113 | 2015 |
| Ablation of AMP-activated protein kinase α1 and α2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo G Sun, AI Tarasov, J McGinty, A McDonald, G da Silva Xavier, T Gorman, ... Diabetologia 53, 924-936, 2010 | 112 | 2010 |
| Sodium-potassium ATPase β1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress M Zatyka, C Ricketts, G da Silva Xavier, J Minton, S Fenton, ... Human molecular genetics 17 (2), 190-200, 2008 | 108 | 2008 |
| Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells RS Fletcher, J Ratajczak, CL Doig, LA Oakey, R Callingham, GDS Xavier, ... Molecular metabolism 6 (8), 819-832, 2017 | 106 | 2017 |
