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Natalie J. Tatum
Natalie J. Tatum
Research Associate, Newcastle University
Verified email at ncl.ac.uk
Title
Cited by
Cited by
Year
The diverse structural landscape of quadruplexes
HL Lightfoot, T Hagen, NJ Tatum, J Hall
FEBS letters 593 (16), 2083-2102, 2019
1162019
Differences in the conformational energy landscape of CDK1 and CDK2 suggest a mechanism for achieving selective CDK inhibition
DJ Wood, S Korolchuk, NJ Tatum, LZ Wang, JA Endicott, MEM Noble, ...
Cell chemical biology 26 (1), 121-130. e5, 2019
942019
Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors
PA Lochhead, JA Tucker, NJ Tatum, J Wang, D Oxley, AM Kidger, ...
Nature communications 11 (1), 1383, 2020
412020
New active leads for tuberculosis booster drugs by structure-based drug discovery
NJ Tatum, JW Liebeschuetz, JC Cole, R Frita, A Herledan, AR Baulard, ...
Organic & Biomolecular Chemistry 15 (48), 10245-10255, 2017
292017
Chatterboxes: the structural and functional diversity of cyclins
NJ Tatum, JA Endicott
Seminars in cell & developmental biology 107, 4-20, 2020
222020
Probing biological activity through structural modelling of ligand-receptor interactions of 2, 4-disubstituted thiazole retinoids
H Haffez, DR Chisholm, NJ Tatum, R Valentine, C Redfern, E Pohl, ...
Bioorganic & medicinal chemistry 26 (8), 1560-1572, 2018
162018
FEN1 blockade for platinum chemo-sensitization and synthetic lethality in epithelial ovarian cancers
KA Mesquita, R Ali, R Doherty, MS Toss, I Miligy, A Alblihy, D Dorjsuren, ...
Cancers 13 (8), 1866, 2021
132021
Structural and docking studies of potent ethionamide boosters
NJ Tatum, B Villemagne, N Willand, B Deprez, JW Liebeschuetz, ...
Acta Crystallographica Section C: Crystal Structure Communications 69 (11 …, 2013
132013
Discriminative SKP2 interactions with CDK-cyclin complexes support a cyclin A-specific role in p27KIP1 degradation
M Salamina, BC Montefiore, M Liu, DJ Wood, R Heath, JR Ault, LZ Wang, ...
Journal of molecular biology 433 (5), 166795, 2021
122021
Synthesis and molecular structure of a perfluorinated pyridyl carbanion
N Colgin, NJ Tatum, E Pohl, SL Cobb, G Sandford
Journal of Fluorine Chemistry 133, 33-37, 2012
102012
Targeting Mre11 overcomes platinum resistance and induces synthetic lethality in XRCC1 deficient epithelial ovarian cancers
A Alblihy, R Ali, M Algethami, A Shoqafi, MS Toss, J Brownlie, NJ Tatum, ...
NPJ precision oncology 6 (1), 51, 2022
82022
Relative Binding Energies Predict Crystallographic Binding Modes of Ethionamide Booster Lead Compounds
NJ Tatum, F Duarte, SCL Kamerlin, E Pohl
The Journal of Physical Chemistry Letters 10, 2244-2249, 2019
62019
Synthesis, Ni (II) Schiff base complexation and structural analysis of fluorinated analogs of the ligand (S)-2-[N-(N′-benzylprolyl) amino] benzophenone (BPB)
NJ Tatum, DS Yufit, SL Cobb, CR Coxon
Journal of Fluorine Chemistry 173, 77-83, 2015
62015
An open-source molecular builder and free energy preparation workflow
MK Bieniek, B Cree, R Pirie, JT Horton, NJ Tatum, DJ Cole
Communications chemistry 5 (1), 136, 2022
22022
Crystallographic fragment screening in academic cancer drug discovery.
MP Martin, JA Endicott, MEM Noble, NJ Tatum
Methods in Enzymology 690, 211-234, 2023
2023
Discovery by Virtual Screening of Ethionamide Boosters for Tuberculosis Treatment
N TATUM
Durham University, 2015
2015
Crystallographic Studies for Structure-Based Drug Design
N TATUM
Durham University, 2012
2012
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