| The SMARCA2/4 ATPase domain surpasses the bromodomain as a drug target in SWI/SNF-mutant cancers: insights from cDNA rescue and PFI-3 inhibitor studies B Vangamudi, TA Paul, PK Shah, M Kost-Alimova, L Nottebaum, X Shi, ... Cancer research 75 (18), 3865-3878, 2015 | 241 | 2015 |
| Discovery of a potent inhibitor of replication protein a protein–protein interactions using a fragment-linking approach AO Frank, MD Feldkamp, JP Kennedy, AG Waterson, NF Pelz, JD Patrone, ... Journal of medicinal chemistry 56 (22), 9242-9250, 2013 | 71 | 2013 |
| Discovery of a potent stapled helix peptide that binds to the 70N domain of replication protein A AO Frank, B Vangamudi, MD Feldkamp, EM Souza-Fagundes, ... Journal of medicinal chemistry 57 (6), 2455-2461, 2014 | 61 | 2014 |
| t-DARPP regulates phosphatidylinositol-3-kinase-dependent cell growth in breast cancer B Vangamudi, DF Peng, Q Cai, W El-Rifai, W Zheng, A Belkhiri Molecular cancer 9, 1-11, 2010 | 41 | 2010 |
| Development of novel cellular histone-binding and chromatin-displacement assays for bromodomain drug discovery Y Zhan, M Kost-Alimova, X Shi, E Leo, JP Bardenhagen, HE Shepard, ... Epigenetics & Chromatin 8, 1-19, 2015 | 37 | 2015 |
| PRMT1-dependent regulation of RNA metabolism and DNA damage response sustains pancreatic ductal adenocarcinoma V Giuliani, MA Miller, CY Liu, SR Hartono, CA Class, CA Bristow, E Suzuki, ... Nature communications 12 (1), 4626, 2021 | 36 | 2021 |
| Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs MR Golder, J Liu, JN Andersen, MV Shipitsin, F Vohidov, HVT Nguyen, ... Nature biomedical engineering 2 (11), 822-830, 2018 | 33 | 2018 |
| Regulation of β-catenin by t-DARPP in upper gastrointestinal cancer cells B Vangamudi, S Zhu, M Soutto, A Belkhiri, W El-Rifai Molecular cancer 10, 1-9, 2011 | 30 | 2011 |
| Discovery of protein–protein interaction inhibitors of replication protein A JD Patrone, JP Kennedy, AO Frank, MD Feldkamp, B Vangamudi, ... ACS medicinal chemistry letters 4 (7), 601-605, 2013 | 29 | 2013 |
| Design of BET inhibitor bottlebrush prodrugs with superior efficacy and devoid of systemic toxicities F Vohidov, JN Andersen, KD Economides, MV Shipitsin, O Burenkova, ... Journal of the American Chemical Society 143 (12), 4714-4724, 2021 | 25 | 2021 |
| Surface reengineering of RPA70N enables cocrystallization with an inhibitor of the replication protein A interaction motif of ATR interacting protein MD Feldkamp, AO Frank, JP Kennedy, JD Patrone, B Vangamudi, ... Biochemistry 52 (37), 6515-6524, 2013 | 23 | 2013 |
| Identification and optimization of anthranilic acid based inhibitors of replication protein A JD Patrone, NF Pelz, BS Bates, EM Souza‐Fagundes, B Vangamudi, ... ChemMedChem 11 (8), 893-899, 2016 | 17 | 2016 |
| Diphenylpyrazoles as replication protein a inhibitors AG Waterson, JP Kennedy, JD Patrone, NF Pelz, MD Feldkamp, AO Frank, ... ACS Medicinal Chemistry Letters 6 (2), 140-145, 2015 | 17 | 2015 |
| Publisher Correction: Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs. MR Golder, J Liu, JN Andersen, MV Shipitsin, F Vohidov, HV Nguyen, ... Nature Biomedical Engineering 2 (9), 707-707, 2018 | 2 | 2018 |
| Design of BET Inhibitor Prodrugs with Superior Efficacy and Devoid of Systemic Toxicities F Vohidov, JN Andersen, KD Economides, MV Shipitsin, O Burenkova, ... | | 2020 |
| Inhibition of protein arginine methylation alters RNA metabolism and DNA damage response providing a new therapeutic strategy in pancreatic ductal adenocarcinoma V Giuliani, A Carugo, M Miller, L Sanz, CY Liu, CA Bristow, E Suzuki, ... Cancer Research 79 (13_Supplement), 277-277, 2019 | | 2019 |
| Development of macromolecular prodrugs of BET-bromodomain inhibitors with superior anti-tumor efficacy that are T-cell sparing and devoid of systemic toxicity F Vohidov, JN Andersen, KD Economides, MV Shipitsin, O Burenkova, ... CANCER RESEARCH 78 (13), 2018 | | 2018 |
| Abstract LB-062: Development of macromolecular prodrugs of BET-bromodomain inhibitors with superior anti-tumor efficacy that are T-cell sparing and devoid of systemic toxicity F Vohidov, JN Andersen, KD Economides, MV Shipitsin, O Burenkova, ... Cancer Research 78 (13_Supplement), LB-062-LB-062, 2018 | | 2018 |
| Identification of protein arginine methyltransferase 1 as novel epigenetic vulnerability in KRAS/p53 mutant PDAC primary patient models V Giuliani, B Vangamudi, E Suzuki, M Miller, CY Liu, A Carugo, C Bristow, ... Cancer Research 77 (13_Supplement), 3016-3016, 2017 | | 2017 |
| Discovery of probes to evaluate the disruption of the protein-protein interactions mediated by RPA70N AG Waterson, P Kennedy, JD Patrone, NF Pelz, AO Frank, B Vangamudi, ... Cancer Research 75 (15_Supplement), 3695-3695, 2015 | | 2015 |
