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michael j shapiro
michael j shapiro
independent scientist
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Year
1, 3-syn diastereoselective reduction of β-hydroxyketones utilizing alkoxydialkylboranes
KM Chen, GE Hardtmann, K Prasad, O Repič, MJ Shapiro
Tetrahedron Letters 28 (2), 155-158, 1987
6221987
Chemical and computational methods for the characterization of covalent reactive groups for the prospective design of irreversible inhibitors
ME Flanagan, JA Abramite, DP Anderson, A Aulabaugh, UP Dahal, ...
Journal of medicinal chemistry 57 (23), 10072-10079, 2014
2802014
Kinomics—structural biology and chemogenomics of kinase inhibitors and targets
M Vieth, RE Higgs, DH Robertson, M Shapiro, EA Gragg, H Hemmerle
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1697 (1-2), 243-257, 2004
2542004
NOE pumping: a novel NMR technique for identification of compounds with binding affinity to macromolecules
A Chen, MJ Shapiro
Journal of the American Chemical Society 120 (39), 10258-10259, 1998
2331998
Diffusion-edited NMR− affinity NMR for direct observation of molecular interactions
M Lin, MJ Shapiro, JR Wareing
Journal of the American Chemical Society 119 (22), 5249-5250, 1997
2121997
The effect of relaxation on the epitope mapping by saturation transfer difference NMR
J Yan, AD Kline, H Mo, MJ Shapiro, ER Zartler
Journal of Magnetic Resonance 163 (2), 270-276, 2003
1802003
Analytical techniques in combinatorial chemistry: MAS CH correlation in solvent-swollen resin
RC Anderson, MA Jarema, MJ Shapiro, JP Stokes, M Ziliox
The Journal of Organic Chemistry 60 (9), 2650-2651, 1995
1761995
NOE pumping. 2. A high-throughput method to determine compounds with binding affinity to macromolecules by NMR
A Chen, MJ Shapiro
Journal of the American Chemical Society 122 (2), 414-415, 2000
1742000
Fragonomics: fragment-based drug discovery
ER Zartler, MJ Shapiro
Current opinion in chemical biology 9 (4), 366-370, 2005
1592005
Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications
A Maderna, M Doroski, C Subramanyam, A Porte, CA Leverett, ...
Journal of medicinal chemistry 57 (24), 10527-10543, 2014
1382014
Screening mixtures by affinity NMR
M Lin, MJ Shapiro, JR Wareing
The Journal of Organic Chemistry 62 (25), 8930-8931, 1997
1381997
Mixture analysis in combinatorial chemistry. Application of diffusion-resolved NMR spectroscopy
M Lin, MJ Shapiro
The Journal of Organic Chemistry 61 (21), 7617-7619, 1996
1371996
Structure determination in combinatorial chemistry: utilization of magic angle spinning HMQC and TOCSY NMR spectra in the structure determination of Wang-bound lysine
RC Anderson, JP Stokes, MJ Shapiro
Tetrahedron letters 36 (30), 5311-5314, 1995
1361995
Pharmacokinetics and metabolism of nateglinide in humans
ML Weaver, BA Orwig, LC Rodriguez, ED Graham, JA Chin, MJ Shapiro, ...
Drug metabolism and disposition 29 (4), 415-421, 2001
1342001
Structures and biological activities of three synaptic antagonists from orb weaver spider venom
ME Adams, RL Carney, FE Enderlin, ET Fu, MA Jarema, JP Li, CA Miller, ...
Biochemical and biophysical research communications 148 (2), 678-683, 1987
1251987
Nuclear magnetic resonance chromatography: applications of pulse field gradient diffusion NMR to mixture analysis and ligand–receptor interactions
JS Gounarides, A Chen, MJ Shapiro
Journal of Chromatography B: Biomedical Sciences and Applications 725 (1), 79-90, 1999
1211999
EPSA: a novel supercritical fluid chromatography technique enabling the design of permeable cyclic peptides
GH Goetz, L Philippe, MJ Shapiro
ACS Medicinal Chemistry Letters 5 (10), 1167-1172, 2014
1202014
2-Chloro-4 (R), 5 (R)-dimethyl-2-oxo-1, 3, 2-dioxaphospholane, a new chiral derivatizing agent
RC Anderson, MJ Shapiro
The Journal of Organic Chemistry 49 (7), 1304-1305, 1984
1151984
Diffusion edited NMR: screening compound mixtures by affinity NMR to detect binding ligands to vancomycin
K Bleicher, M Lin, MJ Shapiro, JR Wareing
The Journal of organic chemistry 63 (23), 8486-8490, 1998
1091998
A novel method for the determination of stereochemistry in six-membered chairlike rings using residual dipolar couplings
J Yan, AD Kline, H Mo, MJ Shapiro, ER Zartler
The Journal of Organic Chemistry 68 (5), 1786-1795, 2003
1052003
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Articles 1–20