1, 3-syn diastereoselective reduction of β-hydroxyketones utilizing alkoxydialkylboranes KM Chen, GE Hardtmann, K Prasad, O Repič, MJ Shapiro Tetrahedron Letters 28 (2), 155-158, 1987 | 622 | 1987 |
Chemical and computational methods for the characterization of covalent reactive groups for the prospective design of irreversible inhibitors ME Flanagan, JA Abramite, DP Anderson, A Aulabaugh, UP Dahal, ... Journal of medicinal chemistry 57 (23), 10072-10079, 2014 | 280 | 2014 |
Kinomics—structural biology and chemogenomics of kinase inhibitors and targets M Vieth, RE Higgs, DH Robertson, M Shapiro, EA Gragg, H Hemmerle Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1697 (1-2), 243-257, 2004 | 254 | 2004 |
NOE pumping: a novel NMR technique for identification of compounds with binding affinity to macromolecules A Chen, MJ Shapiro Journal of the American Chemical Society 120 (39), 10258-10259, 1998 | 233 | 1998 |
Diffusion-edited NMR− affinity NMR for direct observation of molecular interactions M Lin, MJ Shapiro, JR Wareing Journal of the American Chemical Society 119 (22), 5249-5250, 1997 | 212 | 1997 |
The effect of relaxation on the epitope mapping by saturation transfer difference NMR J Yan, AD Kline, H Mo, MJ Shapiro, ER Zartler Journal of Magnetic Resonance 163 (2), 270-276, 2003 | 180 | 2003 |
Analytical techniques in combinatorial chemistry: MAS CH correlation in solvent-swollen resin RC Anderson, MA Jarema, MJ Shapiro, JP Stokes, M Ziliox The Journal of Organic Chemistry 60 (9), 2650-2651, 1995 | 176 | 1995 |
NOE pumping. 2. A high-throughput method to determine compounds with binding affinity to macromolecules by NMR A Chen, MJ Shapiro Journal of the American Chemical Society 122 (2), 414-415, 2000 | 174 | 2000 |
Fragonomics: fragment-based drug discovery ER Zartler, MJ Shapiro Current opinion in chemical biology 9 (4), 366-370, 2005 | 159 | 2005 |
Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications A Maderna, M Doroski, C Subramanyam, A Porte, CA Leverett, ... Journal of medicinal chemistry 57 (24), 10527-10543, 2014 | 138 | 2014 |
Screening mixtures by affinity NMR M Lin, MJ Shapiro, JR Wareing The Journal of Organic Chemistry 62 (25), 8930-8931, 1997 | 138 | 1997 |
Mixture analysis in combinatorial chemistry. Application of diffusion-resolved NMR spectroscopy M Lin, MJ Shapiro The Journal of Organic Chemistry 61 (21), 7617-7619, 1996 | 137 | 1996 |
Structure determination in combinatorial chemistry: utilization of magic angle spinning HMQC and TOCSY NMR spectra in the structure determination of Wang-bound lysine RC Anderson, JP Stokes, MJ Shapiro Tetrahedron letters 36 (30), 5311-5314, 1995 | 136 | 1995 |
Pharmacokinetics and metabolism of nateglinide in humans ML Weaver, BA Orwig, LC Rodriguez, ED Graham, JA Chin, MJ Shapiro, ... Drug metabolism and disposition 29 (4), 415-421, 2001 | 134 | 2001 |
Structures and biological activities of three synaptic antagonists from orb weaver spider venom ME Adams, RL Carney, FE Enderlin, ET Fu, MA Jarema, JP Li, CA Miller, ... Biochemical and biophysical research communications 148 (2), 678-683, 1987 | 125 | 1987 |
Nuclear magnetic resonance chromatography: applications of pulse field gradient diffusion NMR to mixture analysis and ligand–receptor interactions JS Gounarides, A Chen, MJ Shapiro Journal of Chromatography B: Biomedical Sciences and Applications 725 (1), 79-90, 1999 | 121 | 1999 |
EPSA: a novel supercritical fluid chromatography technique enabling the design of permeable cyclic peptides GH Goetz, L Philippe, MJ Shapiro ACS Medicinal Chemistry Letters 5 (10), 1167-1172, 2014 | 120 | 2014 |
2-Chloro-4 (R), 5 (R)-dimethyl-2-oxo-1, 3, 2-dioxaphospholane, a new chiral derivatizing agent RC Anderson, MJ Shapiro The Journal of Organic Chemistry 49 (7), 1304-1305, 1984 | 115 | 1984 |
Diffusion edited NMR: screening compound mixtures by affinity NMR to detect binding ligands to vancomycin K Bleicher, M Lin, MJ Shapiro, JR Wareing The Journal of organic chemistry 63 (23), 8486-8490, 1998 | 109 | 1998 |
A novel method for the determination of stereochemistry in six-membered chairlike rings using residual dipolar couplings J Yan, AD Kline, H Mo, MJ Shapiro, ER Zartler The Journal of Organic Chemistry 68 (5), 1786-1795, 2003 | 105 | 2003 |