Piezo1 integration of vascular architecture with physiological force J Li, B Hou, S Tumova, K Muraki, A Bruns, MJ Ludlow, A Sedo, AJ Hyman, ... Nature 515 (7526), 279-282, 2014 | 968 | 2014 |
Orai1 and CRAC Channel Dependence of VEGF-Activated Ca2+ Entry and Endothelial Tube Formation J Li, RM Cubbon, LA Wilson, MS Amer, L McKeown, B Hou, Y Majeed, ... Circulation research 108 (10), 1190-1198, 2011 | 210 | 2011 |
Pregnenolone sulphate-and cholesterol-regulated TRPM3 channels coupled to vascular smooth muscle secretion and contraction J Naylor, J Li, CJ Milligan, F Zeng, P Sukumar, B Hou, A Sedo, ... Circulation research 106 (9), 1507-1515, 2010 | 178 | 2010 |
Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels HN Rubaiy, MJ Ludlow, M Henrot, HJ Gaunt, K Miteva, SY Cheung, ... Journal of Biological Chemistry 292 (20), 8158-8173, 2017 | 94 | 2017 |
Nanomolar potency and selectivity of a Ca2+ release‐activated Ca2+ channel inhibitor against store‐operated Ca2+ entry and migration of vascular smooth … J Li, L McKeown, O Ojelabi, M Stacey, R Foster, D O'Regan, KE Porter, ... British journal of pharmacology 164 (2), 382-393, 2011 | 75 | 2011 |
Stereo‐selective inhibition of transient receptor potential TRPC5 cation channels by neuroactive steroids Y Majeed, MS Amer, AK Agarwal, L McKeown, KE Porter, DJ O'Regan, ... British journal of pharmacology 162 (7), 1509-1520, 2011 | 61 | 2011 |
Inhibition of endothelial cell Ca2+ entry and transient receptor potential channels by Sigma‐1 receptor ligands MS Amer, L McKeown, S Tumova, R Liu, VAL Seymour, LA Wilson, ... British journal of pharmacology 168 (6), 1445-1455, 2013 | 56 | 2013 |
Orai3 surface accumulation and calcium entry evoked by vascular endothelial growth factor J Li, AF Bruns, B Hou, B Rode, PJ Webster, MA Bailey, HL Appleby, ... Arteriosclerosis, Thrombosis, and Vascular Biology 35 (9), 1987-1994, 2015 | 38 | 2015 |
TRPC5 channel sensitivities to antioxidants and hydroxylated stilbenes J Naylor, ALS Eman, L McKeown, PT Manna, KE Porter, D O'Regan, ... Journal of biological chemistry 286 (7), 5078-5086, 2011 | 38 | 2011 |
Surface expression and distribution of voltage-gated potassium channels in neurons L McKeown, L Swanton, P Robinson, OT Jones Molecular membrane biology 25 (4), 332-343, 2008 | 36 | 2008 |
Rab46 integrates Ca2+ and histamine signaling to regulate selective cargo release from Weibel-Palade bodies KT Miteva, L Pedicini, LA Wilson, I Jayasinghe, RG Slip, K Marszalek, ... Journal of Cell Biology 218 (7), 2232-2246, 2019 | 34 | 2019 |
Expression of a long variant of CRACR2A that belongs to the Rab GTPase protein family in endothelial cells LA Wilson, L McKeown, S Tumova, J Li, DJ Beech Biochemical and Biophysical Research Communications 456 (1), 398-402, 2015 | 27 | 2015 |
LV-pIN-KDEL: a novel lentiviral vector demonstrates the morphology, dynamics and continuity of the endoplasmic reticulum in live neurones VC Jones, L McKeown, A Verkhratsky, OT Jones BMC neuroscience 9, 1-12, 2008 | 26 | 2008 |
Molecular basis of inherited calcium channelopathies: role of mutations in pore‐forming subunits1 L Mckeown, P Robinson, OT Jones Acta Pharmacologica Sinica 27 (7), 799-812, 2006 | 23 | 2006 |
PIN-G–a novel reporter for imaging and defining the effects of trafficking signals in membrane proteins L McKeown, P Robinson, SM Greenwood, W Hu, OT Jones BMC biotechnology 6, 1-11, 2006 | 17 | 2006 |
Identification of an evolutionarily conserved extracellular threonine residue critical for surface expression and its potential coupling of adjacent voltage-sensing and gating … L Mckeown, MP Burnham, C Hodson, OT Jones Journal of biological chemistry 283 (44), 30421-30432, 2008 | 16 | 2008 |
Biallelic mutations in calcium release activated channel regulator 2A (CRACR2A) cause a primary immunodeficiency disorder SS Beibei Wu # 1, Laura Rice # 2, Jennifer Shrimpton 3, Dylan Lawless 4 ... eLife 10, 2021 | 10 | 2021 |
Homotypic endothelial nanotubes induced by wheat germ agglutinin and thrombin L Pedicini, KT Miteva, V Hawley, HJ Gaunt, HL Appleby, RM Cubbon, ... Scientific reports 8 (1), 7569, 2018 | 10 | 2018 |
Platelet-derived growth factor maintains stored calcium through a nonclustering Orai1 mechanism but evokes clustering if the endoplasmic reticulum is stressed by store depletion L McKeown, NK Moss, P Turner, J Li, N Heath, D Burke, D O'Regan, ... Circulation research 111 (1), 66-76, 2012 | 9 | 2012 |
Affinity-based proteomics reveals novel binding partners for Rab46 in endothelial cells L Pedicini, SD Wiktor, KJ Simmons, A Money, L McKeown Scientific Reports 11 (1), 4054, 2021 | 8 | 2021 |