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lynn mckeown
lynn mckeown
Associate Professor in Vascular Cell Biology
Verified email at leeds.ac.uk
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Cited by
Cited by
Year
Piezo1 integration of vascular architecture with physiological force
J Li, B Hou, S Tumova, K Muraki, A Bruns, MJ Ludlow, A Sedo, AJ Hyman, ...
Nature 515 (7526), 279-282, 2014
9682014
Orai1 and CRAC Channel Dependence of VEGF-Activated Ca2+ Entry and Endothelial Tube Formation
J Li, RM Cubbon, LA Wilson, MS Amer, L McKeown, B Hou, Y Majeed, ...
Circulation research 108 (10), 1190-1198, 2011
2102011
Pregnenolone sulphate-and cholesterol-regulated TRPM3 channels coupled to vascular smooth muscle secretion and contraction
J Naylor, J Li, CJ Milligan, F Zeng, P Sukumar, B Hou, A Sedo, ...
Circulation research 106 (9), 1507-1515, 2010
1782010
Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels
HN Rubaiy, MJ Ludlow, M Henrot, HJ Gaunt, K Miteva, SY Cheung, ...
Journal of Biological Chemistry 292 (20), 8158-8173, 2017
942017
Nanomolar potency and selectivity of a Ca2+ release‐activated Ca2+ channel inhibitor against store‐operated Ca2+ entry and migration of vascular smooth …
J Li, L McKeown, O Ojelabi, M Stacey, R Foster, D O'Regan, KE Porter, ...
British journal of pharmacology 164 (2), 382-393, 2011
752011
Stereo‐selective inhibition of transient receptor potential TRPC5 cation channels by neuroactive steroids
Y Majeed, MS Amer, AK Agarwal, L McKeown, KE Porter, DJ O'Regan, ...
British journal of pharmacology 162 (7), 1509-1520, 2011
612011
Inhibition of endothelial cell Ca2+ entry and transient receptor potential channels by Sigma‐1 receptor ligands
MS Amer, L McKeown, S Tumova, R Liu, VAL Seymour, LA Wilson, ...
British journal of pharmacology 168 (6), 1445-1455, 2013
562013
Orai3 surface accumulation and calcium entry evoked by vascular endothelial growth factor
J Li, AF Bruns, B Hou, B Rode, PJ Webster, MA Bailey, HL Appleby, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 35 (9), 1987-1994, 2015
382015
TRPC5 channel sensitivities to antioxidants and hydroxylated stilbenes
J Naylor, ALS Eman, L McKeown, PT Manna, KE Porter, D O'Regan, ...
Journal of biological chemistry 286 (7), 5078-5086, 2011
382011
Surface expression and distribution of voltage-gated potassium channels in neurons
L McKeown, L Swanton, P Robinson, OT Jones
Molecular membrane biology 25 (4), 332-343, 2008
362008
Rab46 integrates Ca2+ and histamine signaling to regulate selective cargo release from Weibel-Palade bodies
KT Miteva, L Pedicini, LA Wilson, I Jayasinghe, RG Slip, K Marszalek, ...
Journal of Cell Biology 218 (7), 2232-2246, 2019
342019
Expression of a long variant of CRACR2A that belongs to the Rab GTPase protein family in endothelial cells
LA Wilson, L McKeown, S Tumova, J Li, DJ Beech
Biochemical and Biophysical Research Communications 456 (1), 398-402, 2015
272015
LV-pIN-KDEL: a novel lentiviral vector demonstrates the morphology, dynamics and continuity of the endoplasmic reticulum in live neurones
VC Jones, L McKeown, A Verkhratsky, OT Jones
BMC neuroscience 9, 1-12, 2008
262008
Molecular basis of inherited calcium channelopathies: role of mutations in pore‐forming subunits1
L Mckeown, P Robinson, OT Jones
Acta Pharmacologica Sinica 27 (7), 799-812, 2006
232006
PIN-G–a novel reporter for imaging and defining the effects of trafficking signals in membrane proteins
L McKeown, P Robinson, SM Greenwood, W Hu, OT Jones
BMC biotechnology 6, 1-11, 2006
172006
Identification of an evolutionarily conserved extracellular threonine residue critical for surface expression and its potential coupling of adjacent voltage-sensing and gating …
L Mckeown, MP Burnham, C Hodson, OT Jones
Journal of biological chemistry 283 (44), 30421-30432, 2008
162008
Biallelic mutations in calcium release activated channel regulator 2A (CRACR2A) cause a primary immunodeficiency disorder
SS Beibei Wu # 1, Laura Rice # 2, Jennifer Shrimpton 3, Dylan Lawless 4 ...
eLife 10, 2021
102021
Homotypic endothelial nanotubes induced by wheat germ agglutinin and thrombin
L Pedicini, KT Miteva, V Hawley, HJ Gaunt, HL Appleby, RM Cubbon, ...
Scientific reports 8 (1), 7569, 2018
102018
Platelet-derived growth factor maintains stored calcium through a nonclustering Orai1 mechanism but evokes clustering if the endoplasmic reticulum is stressed by store depletion
L McKeown, NK Moss, P Turner, J Li, N Heath, D Burke, D O'Regan, ...
Circulation research 111 (1), 66-76, 2012
92012
Affinity-based proteomics reveals novel binding partners for Rab46 in endothelial cells
L Pedicini, SD Wiktor, KJ Simmons, A Money, L McKeown
Scientific Reports 11 (1), 4054, 2021
82021
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