The ABCs of drug transport in intestine and liver: efflux proteins limiting drug absorption and bioavailability LMS Chan, S Lowes, BH Hirst European journal of pharmaceutical sciences 21 (1), 25-51, 2004 | 779 | 2004 |
Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators J Hunter, MA Jepson, T Tsuruo, NL Simmons, BH Hirst Journal of Biological Chemistry 268 (20), 14991-14997, 1993 | 500 | 1993 |
M-Cell Surface β1 Integrin Expression and Invasin-Mediated Targeting of Yersinia pseudotuberculosis to Mouse Peyer’s Patch M Cells MA Clark, BH Hirst, MA Jepson Infection and immunity 66 (3), 1237-1243, 1998 | 481 | 1998 |
Intestinal secretion of drugs. The role of P-glycoprotein and related drug efflux systems in limiting oral drug absorption J Hunter, BH Hirst Advanced drug delivery reviews 25 (2-3), 129-157, 1997 | 381 | 1997 |
Lectin-mediated mucosal delivery of drugs and microparticles MA Clark, BH Hirst, MA Jepson Advanced drug delivery reviews 43 (2-3), 207-223, 2000 | 308 | 2000 |
Exploiting M cells for drug and vaccine delivery MA Clark, MA Jepson, BH Hirst Advanced drug delivery reviews 50 (1-2), 81-106, 2001 | 305 | 2001 |
Preferential interaction of Salmonella typhimurium with mouse Peyer's patch M cells MA Clark, MA Jepson, NL Simmons, BH Hirst Research in microbiology 145 (7), 543-552, 1994 | 304 | 1994 |
Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers J Hunter, BH Hirst, NL Simmons Pharmaceutical research 10, 743-749, 1993 | 295 | 1993 |
Differential expression of lectin-binding sites defines mouse intestinal M-cells. MA Clark, MA Jepson, NL Simmons, TA Booth, BH Hirst Journal of Histochemistry & Cytochemistry 41 (11), 1679-1687, 1993 | 280 | 1993 |
Pili mediate specific adhesion of Streptococcus pyogenes to human tonsil and skin EL Abbot, WD Smith, GPS Siou, C Chiriboga, RJ Smith, JA Wilson, ... Cellular microbiology 9 (7), 1822-1833, 2007 | 261 | 2007 |
Ulex europaeus 1 lectin targets microspheres to mouse Peyer's patch M-cells in vivo N Foster, MA Clark, MA Jepson, BH Hirst Vaccine 16 (5), 536-541, 1998 | 198 | 1998 |
Substrate upregulation of the human small intestinal peptide transporter, hPepT1 D Walker, DT Thwaites, NL Simmons, HJ Gilbert, BH Hirst The Journal of physiology 507 (3), 697-706, 1998 | 194 | 1998 |
Evidence for a general role for non-catalytic thermostabilizing domains in xylanases from thermophilic bacteria C Fontes, GP Hazlewood, E Morag, J Hall, BH Hirst, HJ Gilbert Biochemical Journal 307 (1), 151-158, 1995 | 188 | 1995 |
Targeting to intestinal M cells. MA Jepson, MA Clark, N Foster, CM Mason, MK Bennett, NL Simmons, ... Journal of Anatomy 189 (Pt 3), 507, 1996 | 176 | 1996 |
Targeting polymerised liposome vaccine carriers to intestinal M cells MA Clark, H Blair, L Liang, RN Brey, D Brayden, BH Hirst Vaccine 20 (1-2), 208-217, 2001 | 175 | 2001 |
Transepithelial glycylsarcosine transport in intestinal Caco-2 cells mediated by expression of H (+)-coupled carriers at both apical and basal membranes. DT Thwaites, CD Brown, BH Hirst, NL Simmons Journal of Biological Chemistry 268 (11), 7640-7642, 1993 | 172 | 1993 |
Increased tyrosine phosphorylation causes redistribution of adherens junction and tight junction proteins and perturbs paracellular barrier function in MDCK epithelia CB Collares-Buzato, MA Jepson, NL Simmons, BH Hirst European journal of cell biology 76 (2), 85-92, 1998 | 171 | 1998 |
M cell targeting by lectins: a strategy for mucosal vaccination and drug delivery MA Jepson, MA Clark, BH Hirst Advanced drug delivery reviews 56 (4), 511-525, 2004 | 167 | 2004 |
Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells HM Prime-Chapman, RA Fearn, AE Cooper, V Moore, BH Hirst Journal of Pharmacology and Experimental Therapeutics 311 (2), 476-484, 2004 | 165 | 2004 |
Comparison of poly (DL-lactide-co-glycolide) and polystyrene microsphere targeting to intestinal M cells MA Jepson, NL Simmons, DT O'Hagan, BH Hirst Journal of drug targeting 11 (5), 269-272, 2003 | 159 | 2003 |