| Inactivation of the Fto gene protects from obesity J Fischer, L Koch, C Emmerling, J Vierkotten, T Peters, JC Brüning, ... Nature 458 (7240), 894-898, 2009 | 1121 | 2009 |
| The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry ME Hess, S Hess, KD Meyer, LAW Verhagen, L Koch, HS Brönneke, ... Nature neuroscience 16 (8), 1042-1048, 2013 | 506 | 2013 |
| Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity L Plum, X Ma, B Hampel, N Balthasar, R Coppari, H Münzberg, ... The Journal of clinical investigation 116 (7), 1886-1901, 2006 | 358 | 2006 |
| Central insulin action regulates peripheral glucose and fat metabolism in mice L Koch, FT Wunderlich, J Seibler, AC Könner, B Hampel, S Irlenbusch, ... The Journal of clinical investigation 118 (6), 2132-2147, 2008 | 337 | 2008 |
| Neuronal IGF‐1 resistance reduces Aβ accumulation and protects against premature death in a model of Alzheimer's disease S Freude, MM Hettich, C Schumann, O Stöhr, L Koch, C Köhler, ... The FASEB Journal 23 (10), 3315-3324, 2009 | 242 | 2009 |
| Randomized trial of intensive bisphosphonate treatment versus symptomatic management in Paget's disease of bone AL Langston, MK Campbell, WD Fraser, GS MacLennan, PL Selby, ... Journal of Bone and Mineral Research 25 (1), 20-31, 2010 | 219 | 2010 |
| Divergent roles of growth factors in the GnRH regulation of puberty in mice SA DiVall, TR Williams, SE Carver, L Koch, JC Brüning, CR Kahn, ... The Journal of clinical investigation 120 (8), 2900-2909, 2010 | 180 | 2010 |
| Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growth N Kloting, L Koch, T Wunderlich, M Kern, K Ruschke, W Krone, ... Diabetes 57 (8), 2074-2082, 2008 | 136 | 2008 |
| Exploring human genomic diversity with gnomAD L Koch Nature Reviews Genetics 21 (8), 448-448, 2020 | 107 | 2020 |
| Epidermal insulin/IGF‐1 signalling control interfollicular morphogenesis and proliferative potential through Rac activation H Stachelscheid, H Ibrahim, L Koch, A Schmitz, M Tscharntke, ... The EMBO journal 27 (15), 2091-2101, 2008 | 83 | 2008 |
| Screening for lncRNA function L Koch Nature Reviews Genetics 18 (2), 70-70, 2017 | 81 | 2017 |
| Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to toll-like receptor-mediated NF-κB activation in macrophages B Chaurasia, J Mauer, L Koch, J Goldau, AS Kock, JC Brüning Molecular and cellular biology 30 (17), 4354-4366, 2010 | 72 | 2010 |
| gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor R Janoschek, L Plum, L Koch, H Münzberg, S Diano, M Shanabrough, ... Proceedings of the National Academy of Sciences 103 (28), 10707-10712, 2006 | 63 | 2006 |
| Targeted deletion of somatotroph insulin-like growth factor-I signaling in a cell-specific knockout mouse model CJ Romero, Y Ng, RM Luque, RD Kineman, L Koch, JC Bruning, ... Molecular Endocrinology 24 (5), 1077-1089, 2010 | 47 | 2010 |
| IGF-IR signaling attenuates the age-related decline of diastolic cardiac function S Moellendorf, C Kessels, L Peiseler, A Raupach, C Jacoby, N Vogt, ... American Journal of Physiology-Endocrinology and Metabolism 303 (2), E213-E222, 2012 | 34 | 2012 |
| African cattle adaptations L Koch Nature Reviews Genetics 21 (12), 718-719, 2020 | 31 | 2020 |
| An epigenetic twist on the missing heritability of complex traits L Koch Nature Reviews Genetics 15 (4), 218-218, 2014 | 27 | 2014 |
| RNA: translated circular RNAs L Koch Nature reviews Genetics 18 (5), 272-273, 2017 | 23 | 2017 |
| Insights into missing heritability L Koch Nature Reviews Genetics 15 (4), 218-218, 2014 | 19 | 2014 |
| Altered splicing in Alzheimer transcriptomes L Koch Nature Reviews Genetics 19 (12), 738-739, 2018 | 17 | 2018 |
