Title
Authors
Ehab A Husain, Charles Mein, Lucia Pozo, Alfredo Blanes, Salvador J Diaz-Cano
Publication date
2011/4/1
Journal name
Modern Pathology
Volume
24
Issue
4
Pages
471-486
Publisher
Nature Publishing Group
Description
Abstract Atypical (dysplastic) melanocytic nevi are clinically heterogeneous malignant
melanoma precursors, for which no topographic analysis of cell kinetic, cell cycle regulators
and microsatellite profile is available. We selected low-grade atypical melanocytic nevi (92),
high-grade atypical melanocytic nevi (41), melanocytic nevi (18 junctional, 25 compound)
and malignant melanomas (16 radial growth phase and 27 vertical growth phase). TP53,
CDKN2A, CDKN1A, and CDKN1B microsatellite patterns were topographically studied ...
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