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Antitumor sterols from the mycelia of Cordyceps sinensis

JW Bok, L Lermer, J Chilton, HG Klingeman… - Phytochemistry, 1999 - Elsevier
... Index Terms: antineoplastic activity; cordyceps sinensis extract; 5alpha,8alpha epidioxy 24
methylcholesta 6,22 dien 3beta dextro glucopyranoside; 5,6 epoxy 24 methylcholesta 7,22 dien
3beta ol; ergosteryl 3 o beta dextro glucopyranoside; 22 dihydroergosteryl 3 o beta dextro ...

Antitumor activity of an extract of Cordyceps sinensis (Berk.) Sacc. against murine tumor cell lines.

J Yoshida, S Takamura, N Yamaguchi… - The Japanese journal …, 1989 - ukpmc.ac.uk
A warm water-extract (ECS) prepared from dried Cordyceps sinensis (Berk.) Sacc., a
Chinese traditional medicine, was tested for antitumor activity in vivo and in vitro. Ehrlich
ascites carcinoma cells (EAC), allogeneic to ICR mice and Meth A fibrosarcoma (Meth A), ...

Hypocholesterolemic effect of hot-water extract from mycelia of Cordyceps sinensis

JH Koh, JM Kim, UJ Chang… - Biological and Pharmaceutical …, 2003 - J-STAGE
This study was conducted to investigate the hypocholesterolemic effect of the hot-water
fraction (HW) from cultured mycelia of Cordyceps sinensis in a 5 l fermenter. The
composition of HW was mainly carbohydrate (83.9%) and protein (11.8%) on a dry basis, ...

Activation of in vivo Kupffer cell function by oral administration of Cordyceps sinensis in rats

K Nakamura, Y Yamaguchi, S Kagota… - The Japanese Journal …, 1999 - J-STAGE
... Manabe et al. have reported similar data that a water extract of Cordyceps sinensis has no effect
on wt. gain, liver wt. or relative liver wt. ... Moreover, no pathological change is observed in the liver
specimens from Cordyceps sinensis extract-treated mice (13). Cowper et al. ...

Inhibitory effect of Cordyceps sinensis on spontaneous liver metastasis of Lewis lung carcinoma and B16 melanoma cells in syngeneic mice

K Nakamura, Y Yamaguchi, S Kagota… - The Japanese Journal …, 1999 - J-STAGE
... an inhibitor of proliferation of human leukemic cells and an inducer of differentiation of these
cells through stimulating the production of interferon-?- and tumor necrosis factor-a (5). Each
laboratory has used a different method to pre- pare the Cordyceps sinensis extract for their ...

Effects of a water‐soluble extract of Cordyceps sinensis on steroidogenesis and capsular morphology of lipid droplets in cultured rat adrenocortical cells

SM Wang, LJ Lee, WW Lin… - Journal of cellular …, 1998 - Wiley Online Library
Abstract Cordyceps sinensiscontains a factor that stimulates corticosteroid production in the
animal model. However, it is not known whether this drug acts directly on the adrenal glands
or indirectly via the hypothalamus-pituitary axis. In the present study, we used primary rat ...

Antioxidant activity of the extracts from fruiting bodies of cultured Cordyceps sinensis

Y Yamaguchi, S Kagota, K Nakamura… - Phytotherapy …, 2000 - Wiley Online Library
... lipoprotein (LDL) was incubated with macrophages in the presence of CuCl 2 (1 µM), the hot
water extract showed a ... These results suggest that the extracts of cultured Cordyceps sinensis
possess potent antioxidant and anti-lipid peroxidation activities and inhibit accumulation ...

Induction of HL-60 apoptosis by ethyl acetate extract of Cordyceps sinensis fungal mycelium

Q Zhang, J Wu, Z Hu… - Life sciences, 2004 - Elsevier
The cultivated mycelium of a Cordyceps sinensis (Cs) fungus was sequentially extracted by
petroleum ether, ethyl acetate (EtOAc), ethanol and water. The EtOAc extract showed the
most potent cytotoxic effect against the proliferation of human premyelocytic leukemia cell ...

Effects of the mycelial extract of cultured Cordyceps sinensis on in vivo hepatic energy metabolism in the mouse.

N Manabe, M Sugimoto, Y Azuma… - Japanese journal of …, 1996 - ncbi.nlm.nih.gov
Mice were given the extract of cultured Cordyceps sinensis (Cs)(200 mg/kg daily, po) for 3
weeks. In vivo phosphorus-31 nuclear magnetic resonance (NMR) spectra of the liver were
acquired at weekly intervals using a surface coil. From 1 to 3 weeks, a consistent increase ...

Antiaging effect of Cordyceps sinensis extract

DB Ji, J Ye, CL Li, YH Wang… - Phytotherapy …, 2009 - Wiley Online Library
Abstract This experiment studied the effect of Cordyceps sinensis extract (CSE) on mice
aged by d-galactose and castrated rats to analyse its antiaging effect. Water maze and step-
down type avoidance tests were used to examine the effect of CSE on learning and ...

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