Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria MR Hepworth, LA Monticelli, TC Fung, CGK Ziegler, S Grunberg, R Sinha, ... Nature 498 (7452), 113-117, 2013 | 846 | 2013 |
TSLP elicits IL-33–independent innate lymphoid cell responses to promote skin inflammation BS Kim, MC Siracusa, SA Saenz, M Noti, LA Monticelli, GF Sonnenberg, ... Science translational medicine 5 (170), 170ra16-170ra16, 2013 | 782 | 2013 |
Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria–specific CD4+ T cells MR Hepworth, TC Fung, SH Masur, JR Kelsen, FM McConnell, J Dubrot, ... Science 348 (6238), 1031-1035, 2015 | 525 | 2015 |
IL-33, a potent inducer of adaptive immunity to intestinal nematodes NE Humphreys, D Xu, MR Hepworth, FY Liew, RK Grencis The Journal of Immunology 180 (4), 2443-2449, 2008 | 505 | 2008 |
Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation LC Osborne, LA Monticelli, TJ Nice, TE Sutherland, MC Siracusa, ... Science 345 (6196), 578-582, 2014 | 278 | 2014 |
Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation LA Monticelli, MD Buck, AL Flamar, SA Saenz, ED Tait Wojno, ... Nature immunology 17 (6), 656-665, 2016 | 255 | 2016 |
Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells DR Withers, MR Hepworth, X Wang, EC Mackley, EE Halford, EE Dutton, ... Nature medicine 22 (3), 319-323, 2016 | 237 | 2016 |
Functional interactions between innate lymphoid cells and adaptive immunity GF Sonnenberg, MR Hepworth Nature Reviews Immunology 19 (10), 599-613, 2019 | 220 | 2019 |
CCR7-dependent trafficking of RORγ+ ILCs creates a unique microenvironment within mucosal draining lymph nodes EC Mackley, S Houston, CL Marriott, EE Halford, B Lucas, V Cerovic, ... Nature communications 6 (1), 5862, 2015 | 209 | 2015 |
Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines MR Hepworth, E Daniłowicz-Luebert, S Rausch, M Metz, C Klotz, ... Proceedings of the National Academy of Sciences 109 (17), 6644-6649, 2012 | 200 | 2012 |
Functional and phenotypic heterogeneity of group 3 innate lymphoid cells F Melo‐Gonzalez, MR Hepworth Immunology 150 (3), 265-275, 2017 | 193 | 2017 |
Oxysterol sensing through the receptor GPR183 promotes the lymphoid-tissue-inducing function of innate lymphoid cells and colonic inflammation J Emgård, H Kammoun, B García-Cassani, J Chesné, SM Parigi, ... Immunity 48 (1), 120-132. e8, 2018 | 172 | 2018 |
A helminth immunomodulator exploits host signaling events to regulate cytokine production in macrophages C Klotz, T Ziegler, AS Figueiredo, S Rausch, MR Hepworth, N Obsivac, ... PLoS pathogens 7 (1), e1001248, 2011 | 163 | 2011 |
Lymphoid-tissue-resident commensal bacteria promote members of the IL-10 cytokine family to establish mutualism TC Fung, NJ Bessman, MR Hepworth, N Kumar, N Shibata, D Kobuley, ... Immunity 44 (3), 634-646, 2016 | 155 | 2016 |
Antigen-presenting ILC3 regulate T cell–dependent IgA responses to colonic mucosal bacteria F Melo-Gonzalez, H Kammoun, E Evren, EE Dutton, M Papadopoulou, ... Journal of Experimental Medicine 216 (4), 728-742, 2019 | 131 | 2019 |
A novel regulatory macrophage induced by a helminth molecule instructs IL-10 in CD4+ T cells and protects against mucosal inflammation T Ziegler, S Rausch, S Steinfelder, C Klotz, MR Hepworth, AA Kühl, ... The Journal of Immunology 194 (4), 1555-1564, 2015 | 105 | 2015 |
The role of sex hormones in the development of Th2 immunity in a gender‐biased model of Trichuris muris infection MR Hepworth, MJ Hardman, RK Grencis European journal of immunology 40 (2), 406-416, 2010 | 103 | 2010 |
Group 3 innate lymphoid cells: communications hubs of the intestinal immune system DR Withers, MR Hepworth Frontiers in immunology 8, 300799, 2017 | 92 | 2017 |
Establishment of nematode infection despite increased Th2 responses and immunopathology after selective depletion of Foxp3+ cells S Rausch, J Huehn, C Loddenkemper, MR Hepworth, C Klotz, ... European journal of immunology 39 (11), 3066-3077, 2009 | 92 | 2009 |
IL-22 mediates host defense against an intestinal intracellular parasite in the absence of IFN-γ at the cost of Th17-driven immunopathology J Stange, MR Hepworth, S Rausch, L Zajic, AA Kühl, C Uyttenhove, ... The Journal of Immunology 188 (5), 2410-2418, 2012 | 77 | 2012 |