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Mark N Adams
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Structure, function and pathophysiology of protease activated receptors
MN Adams, R Ramachandran, MK Yau, JY Suen, DP Fairlie, ...
Pharmacology & therapeutics, 2011
4522011
Nucleophosmin: from structure and function to disease development
JK Box, N Paquet, MN Adams, D Boucher, E Bolderson, KJ O’Byrne, ...
BMC molecular biology 17, 1-12, 2016
2572016
Chemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promising
C Jekimovs, E Bolderson, A Suraweera, M Adams, KJ O’Byrne, ...
Frontiers in oncology 4, 86, 2014
1352014
Proteolysis-induced n-terminal ectodomain shedding of the integral membrane glycoprotein CUB domain-containing protein 1 (CDCP1) is accompanied by tyrosine phosphorylation of …
Y He, A Wortmann, LJ Burke, JC Reid, MN Adams, I Abdul-Jabbar, ...
Journal of Biological Chemistry 285 (34), 26162-26173, 2010
812010
Expression of CDCA3 is a prognostic biomarker and potential therapeutic target in non–small cell lung cancer
MN Adams, JT Burgess, Y He, K Gately, C Snell, SD Zhang, JD Hooper, ...
Journal of Thoracic Oncology 12 (7), 1071-1084, 2017
702017
The Role of Palmitoylation in Signalling, Cellular Trafficking and Plasma Membrane Localization of Protease-Activated Receptor-2
MN Adams, ME Christensen, Y He, NJ Waterhouse, JD Hooper
PLoS One 6 (11), e28018, 2011
572011
Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance
Y He, AC Wu, BS Harrington, CM Davies, SJ Wallace, MN Adams, ...
Oncogene 35 (4), 468-478, 2016
562016
Cell line and patient-derived xenograft models reveal elevated CDCP1 as a target in high-grade serous ovarian cancer
BS Harrington, Y He, CM Davies, SJ Wallace, MN Adams, EA Beaven, ...
British journal of cancer 114 (4), 417-426, 2016
522016
Prostatic trypsin-like kallikrein-related peptidases (KLKs) and other prostate-expressed tryptic proteinases as regulators of signalling via proteinase-activated receptors (PARs)
AJ Ramsay, JC Reid, MN Adams, H Samaratunga, Y Dong, JA Clements, ...
Biological chemistry 389 (6), 653-668, 2008
512008
hSSB1 (NABP2/OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway
N Paquet, MN Adams, V Leong, NW Ashton, C Touma, R Gamsjaeger, ...
Nucleic acids research 43 (18), 8817-8829, 2015
472015
Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage
E Bolderson, JT Burgess, J Li, NS Gandhi, D Boucher, LV Croft, S Beard, ...
Nature communications 10 (1), 5501, 2019
442019
Epidermal growth factor receptor (EGFR)-mutated non-small-cell lung cancer (NSCLC)
C O’Leary, H Gasper, KB Sahin, M Tang, A Kulasinghe, MN Adams, ...
Pharmaceuticals 13 (10), 273, 2020
392020
hSSB1 (NABP2/OBFC2B) is regulated by oxidative stress
N Paquet, MN Adams, NW Ashton, C Touma, R Gamsjaeger, L Cubeddu, ...
Scientific reports 6 (1), 27446, 2016
392016
SARS-CoV-2 DNA vaccine INO-4800 induces durable immune responses capable of being boosted in a phase 1 open-label trial
KA Kraynyak, E Blackwood, J Agnes, P Tebas, M Giffear, D Amante, ...
The Journal of infectious diseases 225 (11), 1923-1932, 2022
382022
EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface
MN Adams, BS Harrington, Y He, CM Davies, SJ Wallace, NP Chetty, ...
Oncogene 34 (11), 1375-1383, 2015
382015
Human single-stranded DNA binding protein 1 (hSSB1, OBFC2B), a critical component of the DNA damage response
LV Croft, E Bolderson, MN Adams, S El-Kamand, R Kariawasam, ...
Seminars in cell & developmental biology 86, 121-128, 2019
372019
CDCP1 enhances Wnt signaling in colorectal cancer promoting nuclear localization of β-catenin and E-cadherin
Y He, CM Davies, BS Harrington, L Hellmers, Y Sheng, A Broomfield, ...
Oncogene 39 (1), 219-233, 2020
312020
A structural analysis of DNA binding by hSSB1 (NABP2/OBFC2B) in solution
C Touma, R Kariawasam, AX Gimenez, RE Bernardo, NW Ashton, ...
Nucleic acids research 44 (16), 7963-7973, 2016
292016
Evaluation of antibodies directed against human protease-activated receptor-2
MN Adams, CN Pagel, EJ Mackie, JD Hooper
Naunyn-Schmiedeberg's archives of pharmacology 385, 861-873, 2012
292012
Targeting NF-κB-mediated inflammatory pathways in cisplatin-resistant NSCLC
SL Ryan, S Beard, MP Barr, K Umezawa, S Heavey, P Godwin, SG Gray, ...
Lung Cancer 135, 217-227, 2019
282019
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