| Mammalian caspases: structure, activation, substrates, and functions during apoptosis WC Earnshaw, LM Martins, SH Kaufmann Annual review of biochemistry 68 (1), 383-424, 1999 | 4127 | 1999 |
| Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease KM Strauss, LM Martins, H Plun-Favreau, FP Marx, S Kautzmann, D Berg, ... Human molecular genetics 14 (15), 2099-2111, 2005 | 759 | 2005 |
| The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif LM Martins, I Iaccarino, T Tenev, S Gschmeissner, NF Totty, NR Lemoine, ... Journal of Biological Chemistry 277 (1), 439-444, 2002 | 739 | 2002 |
| Links between air pollution and COVID-19 in England M Travaglio, Y Yu, R Popovic, L Selley, NS Leal, LM Martins Environmental pollution 268, 115859, 2021 | 685 | 2021 |
| The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1 H Plun-Favreau, K Klupsch, N Moisoi, S Gandhi, S Kjaer, D Frith, ... Nature cell biology 9 (11), 1243-1252, 2007 | 588 | 2007 |
| PINK1 cleavage at position A103 by the mitochondrial protease PARL E Deas, H Plun-Favreau, S Gandhi, H Desmond, S Kjaer, SHY Loh, ... Human molecular genetics 20 (5), 867-879, 2011 | 566 | 2011 |
| Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice LM Martins, A Morrison, K Klupsch, V Fedele, N Moisoi, P Teismann, ... Molecular and cellular biology, 2004 | 507 | 2004 |
| The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner J Zhao, T Tenev, LM Martins, J Downward, NR Lemoine Journal of cell science 113 (23), 4363-4371, 2000 | 436 | 2000 |
| Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions CM Eischen, TJ Kottke, LM Martins, GS Basi, JS Tung, WC Earnshaw, ... Blood, The Journal of the American Society of Hematology 90 (3), 935-943, 1997 | 326 | 1997 |
| Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis M Rytömaa, LM Martins, J Downward Current Biology 9 (18), S1-S2, 1999 | 272 | 1999 |
| Specific downregulation of bcl-2 and xIAP by RNAi enhances the effects of chemotherapeutic agents in MCF-7 human breast cancer cells RT Lima, LM Martins, JE Guimaraes, C Sambade, MH Vasconcelos Cancer gene therapy 11 (5), 309-316, 2004 | 270 | 2004 |
| Activation of multiple interleukin-1β converting enzyme homologues in cytosol and nuclei of HL-60 cells during etoposide-induced apoptosis LM Martins, T Kottke, PW Mesner, GS Basi, S Sinha, N Frigon, E Tatar, ... Journal of Biological Chemistry 272 (11), 7421-7430, 1997 | 240 | 1997 |
| The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death S Baksh, S Tommasi, S Fenton, CY Victor, LM Martins, GP Pfeifer, F Latif, ... Molecular cell 18 (6), 637-650, 2005 | 233 | 2005 |
| Mitochondrial dysfunction triggered by loss of HtrA2 results in the activation of a brain-specific transcriptional stress response N Moisoi, K Klupsch, V Fedele, P East, S Sharma, A Renton, ... Cell Death & Differentiation 16 (3), 449-464, 2009 | 211 | 2009 |
| Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS CE Hall, Z Yao, M Choi, GE Tyzack, A Serio, R Luisier, J Harley, E Preza, ... Cell reports 19 (9), 1739-1749, 2017 | 203 | 2017 |
| Cancer and neurodegeneration: between the devil and the deep blue sea H Plun-Favreau, PA Lewis, J Hardy, LM Martins, NW Wood PLoS genetics 6 (12), e1001257, 2010 | 195 | 2010 |
| Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson’s disease I Celardo, AC Costa, S Lehmann, C Jones, N Wood, NE Mencacci, ... Cell death & disease 7 (6), e2271-e2271, 2016 | 178 | 2016 |
| Comparison of caspase activation and subcellular localization in HL-60 and K562 cells undergoing etoposide-induced apoptosis LM Martins, PW Mesner, TJ Kottke, GS Basi, S Sinha, JS Tung, ... Blood, The Journal of the American Society of Hematology 90 (11), 4283-4296, 1997 | 172 | 1997 |
| Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson’s disease R Tufi, S Gandhi, IP De Castro, S Lehmann, PR Angelova, D Dinsdale, ... Nature cell biology 16 (2), 157, 2014 | 168 | 2014 |
| Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi LM Martins, BE Turk, V Cowling, A Borg, ET Jarrell, LC Cantley, ... Journal of Biological Chemistry 278 (49), 49417-49427, 2003 | 165 | 2003 |
Samantha LohDr. Samantha Loh, University of CambridgeVerified email at cam.ac.uk
