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Saffie Mohran
Saffie Mohran
Other namesSaffie E. Mohran
Verified email at uw.edu
Title
Cited by
Cited by
Year
Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin
JD Powers, CC Yuan, KJ McCabe, JD Murray, MC Childers, GV Flint, ...
Proceedings of the National Academy of Sciences 116 (23), 11502-11507, 2019
372019
Danicamtiv increases myosin recruitment and alters cross-bridge cycling in cardiac muscle
KB Kooiker, S Mohran, KL Turner, W Ma, A Martinson, G Flint, L Qi, C Gao, ...
Circulation Research 133 (5), 430-443, 2023
7*2023
Doppler assessment of diastolic function reflect the severity of injury in rats with chronic heart failure
P Sanchez, JJ Lancaster, K Weigand, SAEE Mohran, S Goldman, ...
Journal of Cardiac Failure 23 (10), 753-761, 2017
52017
Epicardially placed bioengineered cardiomyocyte xenograft in immune-competent rat model of heart failure
IR Chinyere, P Bradley, J Uhlorn, J Eason, S Mohran, GG Repetti, ...
Stem cells international 2021, 1-9, 2021
42021
The biochemically defined super relaxed state of myosin—a paradox
S Mohran, K Kooiker, M Mahoney-Schaefer, C Mandrycky, K Kao, AY Tu, ...
Journal of Biological Chemistry 300 (1), 2024
32024
Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration
S Lee, AS Vander Roest, CA Blair, K Kao, SB Bremner, MC Childers, ...
Proceedings of the National Academy of Sciences 121 (19), e2318413121, 2024
1*2024
Measuring the Contractile Kinetics of Isolated Myofibrils from Human-Induced Pluripotent Stem Cell Derived Cardiomyocyte (hiPSC-CM) Models of Cardiomyopathy
S Mohran, S Steczina, C Mandrycky, K Kao, M Regnier
Familial Cardiomyopathies: Methods and Protocols, 213-233, 2023
12023
Structure-Function Investigation of the E258K-Mybpc3 Mutation in HCM Patient-Derived Cardiomyocytes
S Steczina, JM Pioner, S Mohran, M Langione, G Vitale, B Scellini, ...
Biophysical Journal 120 (3), 253a-254a, 2021
12021
Cardiac grafts engineered from human induced pluripotent stem cell ventricular pure or heterogeneous cardiomyocytes display synchronous and spontaneous contraction and reduce …
JJ Lancaster, J Koevary, IR Chinyere, SAE Mohran, EB Juneman, ...
Circulation Research 121 (suppl_1), A344-A344, 2017
12017
MYBPC3-c. 772G> a mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic …
S Sonette, S Mohran, LRJ Bailey, TS McMillen, KB Kooiker, NB Wood, ...
Journal of Molecular and Cellular Cardiology, 2024
2024
The effect of small molecule myosin inhibitors on ATP cycling in porcine cardiac muscle using stopped-flow spectroscopy and in vitro motility
M Mahoney-Schaefer, KB Kooiker, S Mohran, GV Flint, M Regnier, ...
Biophysical Journal 123 (3), 266a-267a, 2024
2024
Mechanisms of myosin, myofibril, and cardiomyocyte dysfunction with the MYH7 R403Q mutation in porcine ventricle muscle
S Mohran, S Steczina, KB Kooiker, T McMillen, C Mandrycky, MC Childers, ...
Biophysical Journal 123 (3), 267a, 2024
2024
Decoupling calcium-dependent thin-filament activation from thick-filament activation in porcine myocardium
S Mohran, C Mandrycky, A Tu, T McMillen, KB Kooiker, W Qian, TC Irving, ...
Biophysical Journal 123 (3), 520a, 2024
2024
MYH3 mutations associated with distal arthrogryposis alter the contractility and myosin isoform switching of hiPSC-derived skeletal muscle
C Mandrycky, S Mohran, MC Childers, SM Luttrell, E Choi, K Buckingham, ...
Biophysical Journal 123 (3), 275a, 2024
2024
A molecular-scale investigation of the mechanisms of contractile dysfunction for the hypertrophic cardiomyopathy MYH7 G256E mutation
KY Kao, MC Childers, S Mohran, M Regnier
Biophysical Journal 123 (3), 267a, 2024
2024
MYBPC3-c. 772G> A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient-induced stem cell-derived cardiomyocyte model of hypertrophic …
S Steczina, S Mohran, L Bailey, T McMillen, KB Kooiker, NB Wood, ...
Biophysical Journal 123 (3), 318a-319a, 2024
2024
2-Deoxy-ATP reduces the cardiac depressive effect of acidosis
MA Redd, TS McMillen, MK Woodward, S Mohran, KB Kooiker, GV Flint, ...
Biophysical Journal 123 (3), 403a-404a, 2024
2024
The effect of small molecule myosin modulators on ATP turnover in pig cardiac HMM using stopped flow spectroscopy
KB Kooiker, S Mohran, M Mahoney-Schaefer, J Freeman, MA Geeves, ...
Biophysical Journal 122 (3), 121a-122a, 2023
2023
The β-myosin G256E mutation impairs relaxation by altering transducer stiffness
MC Childers, KY Kao, S Mohran, M Regnier
Biophysical Journal 122 (3), 402a, 2023
2023
Muscle length alters activation kinetics in fast-twitch edl muscle and relaxation kinetics in slow-twitch soleus muscle
S Mohran, HM Gong, M Regnier, TC Irving, W Ma
Biophysical Journal 122 (3), 28a, 2023
2023
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