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Joseph Wedekind
Joseph Wedekind
University of Rochester School of Medicine and Dentistry
Verified email at rochester.edu - Homepage
Title
Cited by
Cited by
Year
The enolase superfamily: a general strategy for enzyme-catalyzed abstraction of the α-protons of carboxylic acids
PC Babbitt, MS Hasson, JE Wedekind, DRJ Palmer, WC Barrett, GH Reed, ...
Biochemistry 35 (51), 16489-16501, 1996
4301996
Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business
JE Wedekind, GSC Dance, MP Sowden, HC Smith
Trends in Genetics 19 (4), 207-216, 2003
4002003
A carboxylate oxygen of the substrate bridges the magnesium ions at the active site of enolase: structure of the yeast enzyme complexed with the equilibrium mixture of 2 …
TM Larsen, JE Wedekind, I Rayment, GH Reed
Biochemistry 35 (14), 4349-4358, 1996
1751996
Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance
AK Ghosh, PR Sridhar, S Leshchenko, AK Hussain, J Li, AY Kovalevsky, ...
Journal of medicinal chemistry 49 (17), 5252-5261, 2006
1702006
Crystal structure of a lead-dependent ribozyme revealing metal binding sites relevant to catalysis
JE Wedekind, DB McKay
Nature structural biology 6 (3), 261-268, 1999
1551999
Refined crystallographic structure of Pseudomonas aeruginosa exotoxin A and its implications for the molecular mechanism of toxicity
JE Wedekind, CB Trame, M Dorywalska, P Koehl, TM Raschke, M McKee, ...
Journal of molecular biology 314 (4), 823-837, 2001
1532001
Comparison of a preQ1 riboswitch aptamer in metabolite-bound and free states with implications for gene regulation
JL Jenkins, J Krucinska, RM McCarty, V Bandarian, JE Wedekind
Journal of Biological Chemistry 286 (28), 24626-24637, 2011
1452011
Chelation of Serine 39 to Mg2+ latches a gate at the active site of enolase: Structure of the Bis (Mg2+) Complex of yeast enolase and the intermediate analog …
JE Wedekind, RR Poyner, GH Reed, I Rayment
Biochemistry 33 (31), 9333-9342, 1994
1341994
The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1
K Xie, MP Sowden, GSC Dance, AT Torelli, HC Smith, JE Wedekind
Proceedings of the National Academy of Sciences 101 (21), 8114-8119, 2004
1322004
Crystallographic structures of the hammerhead ribozyme: relationship to ribozyme folding and catalysis
JE Wedekind, DB McKay
Annual review of biophysics and biomolecular structure 27 (1), 475-502, 1998
1321998
Nanostructures of APOBEC3G support a hierarchical assembly model of high molecular mass ribonucleoprotein particles from dimeric subunits
JE Wedekind, R Gillilan, A Janda, J Krucinska, JD Salter, RP Bennett, ...
Journal of biological chemistry 281 (50), 38122-38126, 2006
1182006
The Structural Basis for Recognition of the PreQ0 Metabolite by an Unusually Small Riboswitch Aptamer Domain*♦
RC Spitale, AT Torelli, J Krucinska, V Bandarian, JE Wedekind
Journal of biological chemistry 284 (17), 11012-11016, 2009
1172009
Structural and mechanistic studies of enolase
GH Reed, RR Poyner, TM Larsen, JE Wedekind, I Rayment
Current opinion in structural biology 6 (6), 736-743, 1996
1091996
Three-Dimensional Structure of Galactose-1-Phosphate Uridylyltransferase from Escherichia Coli at 1.8. ANG. Resolution
JE Wedekind, PA Frey, I Rayment
Biochemistry 34 (35), 11049-11061, 1995
1081995
Water in the Active Site of an All-RNA Hairpin Ribozyme and Effects of Gua8 Base Variants on the Geometry of Phosphoryl Transfer,
J Salter, J Krucinska, S Alam, V Grum-Tokars, JE Wedekind
Biochemistry 45 (3), 686-700, 2006
1052006
Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound …
KC Suddala, AJ Rinaldi, J Feng, AM Mustoe, CD Eichhorn, JA Liberman, ...
Nucleic acids research 41 (22), 10462-10475, 2013
1002013
Crystal structure of the leadzyme at 1.8 Å resolution: Metal ion binding and the implications for catalytic mechanism and allo site ion regulation
JE Wedekind, DB McKay
Biochemistry 42 (32), 9554-9563, 2003
1002003
Crystal structure of the leadzyme at 1.8 Å resolution: Metal ion binding and the implications for catalytic mechanism and allo site ion regulation
JE Wedekind, DB McKay
Biochemistry 42 (32), 9554-9563, 2003
1002003
The Structure of Nucleotidylated Histidine-166 of Galactose-1-phosphate Uridylyltransferase Provides Insight into Phosphoryl Group Transfer,
JE Wedekind, PA Frey, I Rayment
Biochemistry 35 (36), 11560-11569, 1996
971996
Structure of a class II preQ1 riboswitch reveals ligand recognition by a new fold
JA Liberman, M Salim, J Krucinska, JE Wedekind
Nature chemical biology 9 (6), 353-355, 2013
952013
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