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Penny Lovat
Penny Lovat
Professor of Cellular Dermatology and Oncology , Newcastle University
Verified email at ncl.ac.uk
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Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13636*2021
Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress
PE Lovat, M Corazzari, JL Armstrong, S Martin, V Pagliarini, D Hill, ...
Cancer research 68 (13), 5363-5369, 2008
2332008
Regulation of endoplasmic reticulum stress-induced cell death by ATF4 in neuroectodermal tumor cells
JL Armstrong, R Flockhart, GJ Veal, PE Lovat, CPF Redfern
Journal of Biological Chemistry 285 (9), 6091-6100, 2010
1902010
Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death
JL Armstrong, DS Hill, CS McKee, S Hernandez-Tiedra, M Lorente, ...
Journal of Investigative Dermatology 135 (6), 1629-1637, 2015
1772015
Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma
M Corazzari, F Rapino, F Ciccosanti, P Giglio, M Antonioli, B Conti, ...
Cell Death & Differentiation 22 (6), 946-958, 2015
1712015
Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
S Hernández-Tiedra, G Fabrias, D Dávila, IJ Salanueva, J Casas, ...
Autophagy 12 (11), 2213-2229, 2016
1612016
Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing
B Carroll, G Nelson, Y Rabanal-Ruiz, O Kucheryavenko, ...
Journal of Cell Biology 216 (7), 1949-1957, 2017
1552017
Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 …
M Corazzari, PE Lovat, JL Armstrong, GM Fimia, DS Hill, M Birch-Machin, ...
British journal of cancer 96 (7), 1062-1071, 2007
1542007
A novel fully humanized 3D skin equivalent to model early melanoma invasion
DS Hill, NDP Robinson, MP Caley, M Chen, EA O'Toole, JL Armstrong, ...
Molecular cancer therapeutics 14 (11), 2665-2673, 2015
1312015
Glucagon-like peptide 1 protects pancreatic β-cells from death by increasing autophagic flux and restoring lysosomal function
FP Zummo, KS Cullen, M Honkanen-Scott, JAM Shaw, PE Lovat, C Arden
Diabetes 66 (5), 1272-1285, 2017
1292017
Effector mechanisms of fenretinide-induced apoptosis in neuroblastoma
PE Lovat, M Ranalli, M Annichiarrico-Petruzzelli, F Bernassola, ...
Experimental cell research 260 (1), 50-60, 2000
1132000
Reduction in skin cancer diagnoses in the UK during the COVID‐19 pandemic
TW Andrew, M Alrawi, P Lovat
Clinical and experimental dermatology 46 (1), 145-146, 2021
1082021
Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78
S Martin, HK Lamb, C Brady, B Lefkove, MY Bonner, P Thompson, ...
British journal of cancer 109 (2), 433-443, 2013
1082013
Gangliosides Link the Acidic Sphingomyelinase–Mediated Induction of Ceramide to 12-Lipoxygenase–Dependent Apoptosis of Neuroblastoma in Response to Fenretinide
PE Lovat, F Di Sano, M Corazzari, B Fazi, RP Donnorso, ADJ Pearson, ...
Journal of the National Cancer Institute 96 (17), 1288-1299, 2004
1022004
NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma
RJ Flockhart, JL Armstrong, NJ Reynolds, PE Lovat
British journal of cancer 101 (8), 1448-1455, 2009
962009
GADD153 and 12-lipoxygenase mediate fenretinide-induced apoptosis of neuroblastoma
PE Lovat, S Oliverio, M Ranalli, M Corazzari, C Rodolfo, F Bernassola, ...
Cancer research 62 (18), 5158-5167, 2002
962002
Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition
JL Armstrong, M Corazzari, S Martin, V Pagliarini, L Falasca, DS Hill, ...
Clinical Cancer Research 17 (8), 2216-2226, 2011
872011
Prognostic impact of autophagy biomarkers for cutaneous melanoma
DYL Tang, RA Ellis, PE Lovat
Frontiers in Oncology 6, 236, 2016
822016
Inhibition of CXCR4–CXCL12 chemotaxis in melanoma by AMD11070
G O'Boyle, I Swidenbank, H Marshall, CE Barker, J Armstrong, SA White, ...
British journal of cancer 108 (8), 1634-1640, 2013
802013
Synergistic induction of apoptosis of neuroblastoma by fenretinide or CD437 in combination with chemotherapeutic drugs
PE Lovat, M Ranalli, F Bernassola, M Tilby, AJ Malcolm, ADJ Pearson, ...
International journal of cancer 88 (6), 977-985, 2000
802000
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