Penny Lovat
Penny Lovat
Professor of Cellular Dermatology and Oncology , Newcastle University
Verified email at
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress
PE Lovat, M Corazzari, JL Armstrong, S Martin, V Pagliarini, D Hill, ...
Cancer research 68 (13), 5363-5369, 2008
Regulation of endoplasmic reticulum stress-induced cell death by ATF4 in neuroectodermal tumor cells
JL Armstrong, R Flockhart, GJ Veal, PE Lovat, CPF Redfern
Journal of Biological Chemistry 285 (9), 6091-6100, 2010
Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 …
M Corazzari, PE Lovat, JL Armstrong, GM Fimia, DS Hill, M Birch-Machin, ...
British journal of cancer 96 (7), 1062-1071, 2007
Exploiting cannabinoid-induced cytotoxic autophagy to drive melanoma cell death
JL Armstrong, DS Hill, CS McKee, S Hernandez-Tiedra, M Lorente, ...
Journal of Investigative Dermatology 135 (6), 1629-1637, 2015
Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma
M Corazzari, F Rapino, F Ciccosanti, P Giglio, M Antonioli, B Conti, ...
Cell Death & Differentiation 22 (6), 946-958, 2015
Effector mechanisms of fenretinide-induced apoptosis in neuroblastoma
PE Lovat, M Ranalli, M Annichiarrico-Petruzzelli, F Bernassola, ...
Experimental cell research 260 (1), 50-60, 2000
Gangliosides Link the Acidic Sphingomyelinase–Mediated Induction of Ceramide to 12-Lipoxygenase–Dependent Apoptosis of Neuroblastoma in Response to Fenretinide
PE Lovat, F Di Sano, M Corazzari, B Fazi, RP Donnorso, ADJ Pearson, ...
Journal of the National Cancer Institute 96 (17), 1288-1299, 2004
Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization
S Hernández-Tiedra, G Fabrias, D Dávila, IJ Salanueva, J Casas, ...
Autophagy 12 (11), 2213-2229, 2016
GADD153 and 12-lipoxygenase mediate fenretinide-induced apoptosis of neuroblastoma
PE Lovat, S Oliverio, M Ranalli, M Corazzari, C Rodolfo, F Bernassola, ...
Cancer research 62 (18), 5158-5167, 2002
Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78
S Martin, HK Lamb, C Brady, B Lefkove, MY Bonner, P Thompson, ...
British journal of cancer 109 (2), 433-443, 2013
NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma
RJ Flockhart, JL Armstrong, NJ Reynolds, PE Lovat
British journal of cancer 101 (8), 1448-1455, 2009
Synergistic induction of apoptosis of neuroblastoma by fenretinide or CD437 in combination with chemotherapeutic drugs
PE Lovat, M Ranalli, F Bernassola, M Tilby, AJ Malcolm, ADJ Pearson, ...
International journal of cancer 88 (6), 977-985, 2000
Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition
JL Armstrong, M Corazzari, S Martin, V Pagliarini, L Falasca, DS Hill, ...
Clinical Cancer Research 17 (8), 2216-2226, 2011
Glucagon-like peptide 1 protects pancreatic β-cells from death by increasing autophagic flux and restoring lysosomal function
FP Zummo, KS Cullen, M Honkanen-Scott, JAM Shaw, PE Lovat, C Arden
Diabetes 66 (5), 1272-1285, 2017
Combining the endoplasmic reticulum stress–inducing agents bortezomib and fenretinide as a novel therapeutic strategy for metastatic melanoma
DS Hill, S Martin, JL Armstrong, R Flockhart, JJ Tonison, DG Simpson, ...
Clinical Cancer Research 15 (4), 1192-1198, 2009
Gene expression and neuroblastoma cell differentiation in response to retinoic acid: differential effects of 9-cis and all-trans retinoic acid
CPF Redfern, PE Lovat, AJ Malcolm, ADJ Pearson
European Journal of Cancer 31 (4), 486-494, 1995
Fenretinide: a p53-independent way to kill cancer cells
M Corazzari, PE Lovat, S Oliverio, F Di Sano, RP Donnorso, CPF Redfern, ...
Biochemical and biophysical research communications 331 (3), 810-815, 2005
Inhibition of CXCR4–CXCL12 chemotaxis in melanoma by AMD11070
G O'Boyle, I Swidenbank, H Marshall, CE Barker, J Armstrong, SA White, ...
British journal of cancer 108 (8), 1634-1640, 2013
Glucosylceramide synthase and its functional interaction with RTN-1C regulate chemotherapeutic-induced apoptosis in neuroepithelioma cells
F Di Sano, B Fazi, G Citro, PE Lovat, G Cesareni, M Piacentini
Cancer research 63 (14), 3860-3865, 2003
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