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Johannes G. Bode
Johannes G. Bode
Professor for Hepatoimmunology, Medical Faculty, Heinrich-Heine University
Verified email at med.uni-duesseldorf.de - Homepage
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Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating …
P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ...
Archives of toxicology 87, 1315-1530, 2013
13902013
Hepatic acute phase proteins–regulation by IL-6-and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling
JG Bode, U Albrecht, D Häussinger, PC Heinrich, F Schaper
European journal of cell biology 91 (6-7), 496-505, 2012
4502012
The macrophage response towards LPS and its control through the p38MAPK–STAT3 axis
JG Bode, C Ehlting, D Häussinger
Cellular signalling 24 (6), 1185-1194, 2012
4362012
Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses
C Ehrhardt, T Wolff, S Pleschka, O Planz, W Beermann, JG Bode, ...
Journal of virology 81 (7), 3058-3067, 2007
4202007
IFN‐α antagonistic activity of HCV core protein involves induction of suppressor of cytokine signaling‐3
JG Bode, S Ludwig, C Ehrhardt, A Erhardt, U Albrecht, F Schaper, ...
The FASEB Journal 17 (3), 1-16, 2003
4142003
Influenza A virus inhibits type I IFN signaling via NF-κB-dependent induction of SOCS-3 expression
EK Pauli, M Schmolke, T Wolff, D Viemann, J Roth, JG Bode, S Ludwig
PLoS pathogens 4 (11), e1000196, 2008
3312008
LPS and TNFα induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages
JG Bode, A Nimmesgern, J Schmitz, F Schaper, M Schmitt, W Frisch, ...
FEBS letters 463 (3), 365-370, 1999
2691999
Regulation of suppressor of cytokine signaling 3 (SOCS3) mRNA stability by TNF-α involves activation of the MKK6/p38MAPK/MK2 cascade
C Ehlting, WS Lai, F Schaper, ED Brenndörfer, RJ Matthes, PC Heinrich, ...
The Journal of Immunology 178 (5), 2813-2826, 2007
1532007
Bile acids PKA-dependently induce a switch of the IL-10/IL-12 ratio and reduce proinflammatory capability of human macrophages
K Haselow, JG Bode, M Wammers, C Ehlting, V Keitel, L Kleinebrecht, ...
Journal of leukocyte biology 94 (6), 1253-1264, 2013
1412013
Expression of the peripheral-type benzodiazepine receptor and apoptosis induction in hepatic stellate cells
R Fischer, M Schmitt, JG Bode, D Häussinger
Gastroenterology 120 (5), 1212-1226, 2001
1402001
BMP-9 interferes with liver regeneration and promotes liver fibrosis
K Breitkopf-Heinlein, C Meyer, C König, H Gaitantzi, A Addante, ...
Gut 66 (5), 939-954, 2017
1282017
Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation
S Radtke, S Wüller, X Yang, BE Lippok, B Mütze, C Mais, HSV de Leur, ...
Journal of cell science 123 (6), 947-959, 2010
1212010
The mitogen-activated protein (MAP) kinase p38 and its upstream activator MAP kinase kinase 6 are involved in the activation of signal transducer and activator of transcription …
JG Bode, P Gatsios, S Ludwig, UR Rapp, D Häussinger, PC Heinrich, ...
Journal of Biological Chemistry 274 (42), 30222-30227, 1999
1201999
Infusion of CD133+ bone marrow–derived stem cells after selective portal vein embolization enhances functional hepatic reserves after extended right hepatectomy: a …
JS am Esch, M Schmelzle, G Fürst, SC Robson, A Krieg, C Duhme, ...
Annals of surgery 255 (1), 79-85, 2012
1122012
The inhibition of interleukin-6-dependent STAT activation by mitogen-activated protein kinases depends on tyrosine 759 in the cytoplasmic tail of glycoprotein 130
L Terstegen, P Gatsios, JG Bode, F Schaper, PC Heinrich, L Graeve
Journal of Biological Chemistry 275 (25), 18810-18817, 2000
1022000
The MKK6/p38 mitogen-activated protein kinase pathway is capable of inducing SOCS3 gene expression and inhibits IL-6-induced transcription
JG Bode, S Ludwig, CAC Freitas, F Schaper, M Ruhl, S Melmed, ...
Walter de Gruyter 382 (10), 1447-1453, 2001
982001
The inhibitory effect of IL-1β on IL-6-induced α2-macroglobulin expression is due to activation of NF-κB
JG Bode, R Fischer, D Häussinger, L Graeve, PC Heinrich, F Schaper
The Journal of Immunology 167 (3), 1469-1481, 2001
962001
Nonstructural 3/4A protease of hepatitis C virus activates epithelial growth factor–induced signal transduction by cleavage of the T‐cell protein tyrosine phosphatase
ED Brenndörfer, J Karthe, L Frelin, P Cebula, A Erhardt, ...
Hepatology 49 (6), 1810-1820, 2009
952009
Hyperammonemia in gene-targeted mice lacking functional hepatic glutamine synthetase
N Qvartskhava, PA Lang, B Görg, VI Pozdeev, MP Ortiz, KS Lang, ...
Proceedings of the National Academy of Sciences 112 (17), 5521-5526, 2015
912015
Molecular aspects of medicine: from experimental to clinical hepatology
D Häussinger, R Kubitz, R Reinehr, JG Bode, F Schliess
Molecular aspects of medicine 25 (3), 221-360, 2004
872004
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