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Jocelynn Pearl
Jocelynn Pearl
Senior Scientist, Tune Therapeutics
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Cited by
Cited by
Year
Translating dosage compensation to trisomy 21
J Jiang, Y Jing, GJ Cost, JC Chiang, HJ Kolpa, AM Cotton, DM Carone, ...
Nature 500 (7462), 296-300, 2013
4082013
Targeted gene addition in human CD34+ hematopoietic cells for correction of X-linked chronic granulomatous disease
SS De Ravin, A Reik, PQ Liu, L Li, X Wu, L Su, C Raley, N Theobald, ...
Nature biotechnology 34 (4), 424-429, 2016
2032016
Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases
J Straimer, MCS Lee, AH Lee, B Zeitler, AE Williams, JR Pearl, L Zhang, ...
Nature methods 9 (10), 993-998, 2012
2022012
De novo design of protein logic gates
Z Chen, RD Kibler, A Hunt, F Busch, J Pearl, M Jia, ZL VanAernum, ...
Science 368 (6486), 78-84, 2020
1752020
Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease
B Zeitler, S Froelich, K Marlen, DA Shivak, Q Yu, D Li, JR Pearl, JC Miller, ...
Nature medicine 25 (7), 1131-1142, 2019
1592019
Transcriptional regulatory networks underlying gene expression changes in Huntington's disease
SA Ament, JR Pearl, JP Cantle, RM Bragg, PJ Skene, SR Coffey, ...
Molecular systems biology 14 (3), e7435, 2018
672018
Genome-scale transcriptional regulatory network models of psychiatric and neurodegenerative disorders
JR Pearl, C Colantuoni, DE Bergey, CC Funk, P Shannon, B Basu, ...
Cell systems 8 (2), 122-135. e7, 2019
512019
High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington’s disease CAG knock-in mice across multiple genetic backgrounds
SA Ament, JR Pearl, A Grindeland, J St. Claire, JC Earls, M Kovalenko, ...
Human molecular genetics 26 (5), 913-922, 2017
432017
Activation domains for controlling plant gene expression using designed transcription factors
J Li, R Blue, B Zeitler, TL Strange, JR Pearl, DH Huizinga, S Evans, ...
Plant biotechnology journal 11 (6), 671-680, 2013
342013
Enhanced retinal responses in Huntington’s disease patients
JR Pearl, LM Heath, DE Bergey, JP Kelly, C Smith, MY Laurino, A Weiss, ...
Journal of Huntington's disease 6 (3), 237-247, 2017
162017
Allele-specific repression of mutant Huntingtin expression by engineered zinc finger transcriptional repressors as a potential therapy for Huntington's disease
B Zeitler, S Froelich, Q Yu, J Pearl, DE Paschon, JC Miller, D Li, K Marlen, ...
Molecular Therapy 22, S233-S233, 2014
92014
Altered Huntingtin-Chromatin Interactions Predict Transcriptional and Epigenetic Changes in Huntington’s Disease
JR Pearl, AC Shetty, JP Cantle, DE Bergey, RM Bragg, SR Coffey, ...
bioRxiv, 2020.06. 04.132571, 2020
42020
Genome-scale transcriptional regulatory network models for the mouse and human striatum predict roles for SMAD3 and other transcription factors in Huntington’s disease
SA Ament, JR Pearl, RM Bragg, PJ Skene, SR Coffey, DE Bergey, ...
bioRxiv, 087114, 2016
22016
Quantitative dialing of gene expression via precision targeting of KRAB repressor
MS Wilken, C Ciarlo, J Pearl, E Schanzer, H Liao, BV Biber, K Queitsch, ...
12020
Potent and timed epigenetic repression of PD-1 in human T cells
J Pearl, FD Urnov, JA Stamatoyannopoulos
Blood 132, 3493, 2018
12018
Genome-Scale Transcriptional Regulatory Network Models of Psychiatric Disorders
S Ament, J Pearl, C Funk, D Bergey, P Shannon, B Basu, L Hood, N Price
European Neuropsychopharmacology 27, S417, 2017
12017
Nucleases For Genome Editing
JA Stamatoyannopoulos, F Urnov, J Pearl, S Thomas
US Patent App. 17/253,863, 2023
2023
A Genome Scale Transcriptional Regulatory Model of the Human Placenta
A Paquette, K Ahuna, YM Hwang, J Pearl, H Liao, P Shannon, L Kadam, ...
bioRxiv, 2022.09. 27.509541, 2022
2022
Characterizing Sex-Specific Differences in Placental Epigenome Using DNase-Sequencing Data.
YM Hwang, AG Paquette, P Shannon, C Funk, J Pearl, H Liao, ...
REPRODUCTIVE SCIENCES 28 (SUPPL 1), 169A-169A, 2021
2021
Characterizing Sex-specific Differences in Placental Epigenome Using DNase-sequencing Data.
YM Hwang, AG Paquette, P Shannon, C Funk, J Pearl, H Liao, ...
REPRODUCTIVE SCIENCES 27 (SUPPL 1), 165A-166A, 2020
2020
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