| Translating dosage compensation to trisomy 21 J Jiang, Y Jing, GJ Cost, JC Chiang, HJ Kolpa, AM Cotton, DM Carone, ... Nature 500 (7462), 296-300, 2013 | 393 | 2013 |
| Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases J Straimer, MCS Lee, AH Lee, B Zeitler, AE Williams, JR Pearl, L Zhang, ... Nature methods 9 (10), 993-998, 2012 | 200 | 2012 |
| Targeted gene addition in human CD34+ hematopoietic cells for correction of X-linked chronic granulomatous disease SS De Ravin, A Reik, PQ Liu, L Li, X Wu, L Su, C Raley, N Theobald, ... Nature biotechnology 34 (4), 424-429, 2016 | 195 | 2016 |
| De novo design of protein logic gates Z Chen, RD Kibler, A Hunt, F Busch, J Pearl, M Jia, ZL VanAernum, ... Science 368 (6486), 78-84, 2020 | 155 | 2020 |
| Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease B Zeitler, S Froelich, K Marlen, DA Shivak, Q Yu, D Li, JR Pearl, JC Miller, ... Nature medicine 25 (7), 1131-1142, 2019 | 148 | 2019 |
| Transcriptional regulatory networks underlying gene expression changes in Huntington's disease SA Ament, JR Pearl, JP Cantle, RM Bragg, PJ Skene, SR Coffey, ... Molecular systems biology 14 (3), e7435, 2018 | 59 | 2018 |
| Genome-scale transcriptional regulatory network models of psychiatric and neurodegenerative disorders JR Pearl, C Colantuoni, DE Bergey, CC Funk, P Shannon, B Basu, ... Cell systems 8 (2), 122-135. e7, 2019 | 46 | 2019 |
| High resolution time-course mapping of early transcriptomic, molecular and cellular phenotypes in Huntington’s disease CAG knock-in mice across multiple genetic backgrounds SA Ament, JR Pearl, A Grindeland, J St. Claire, JC Earls, M Kovalenko, ... Human molecular genetics 26 (5), 913-922, 2017 | 41 | 2017 |
| Activation domains for controlling plant gene expression using designed transcription factors J Li, R Blue, B Zeitler, TL Strange, JR Pearl, DH Huizinga, S Evans, ... Plant biotechnology journal 11 (6), 671-680, 2013 | 33 | 2013 |
| Enhanced retinal responses in Huntington’s disease patients JR Pearl, LM Heath, DE Bergey, JP Kelly, C Smith, MY Laurino, A Weiss, ... Journal of Huntington's disease 6 (3), 237-247, 2017 | 15 | 2017 |
| Allele-specific repression of mutant Huntingtin expression by engineered zinc finger transcriptional repressors as a potential therapy for Huntington's disease B Zeitler, S Froelich, Q Yu, J Pearl, DE Paschon, JC Miller, D Li, K Marlen, ... Molecular Therapy 22, S233-S233, 2014 | 9 | 2014 |
| Altered Huntingtin-Chromatin Interactions Predict Transcriptional and Epigenetic Changes in Huntington’s Disease JR Pearl, AC Shetty, JP Cantle, DE Bergey, RM Bragg, SR Coffey, ... bioRxiv, 2020.06. 04.132571, 2020 | 4 | 2020 |
| Genome-scale transcriptional regulatory network models for the mouse and human striatum predict roles for SMAD3 and other transcription factors in Huntington’s disease SA Ament, JR Pearl, RM Bragg, PJ Skene, SR Coffey, DE Bergey, ... bioRxiv, 087114, 2016 | 2 | 2016 |
| Quantitative dialing of gene expression via precision targeting of KRAB repressor MS Wilken, C Ciarlo, J Pearl, E Schanzer, H Liao, BV Biber, K Queitsch, ... | 1 | 2020 |
| Promoter keyholes enable specific and persistent multi-gene expression programs in primary T cells without genome modification MS Wilken, C Ciarlo, J Pearl, J Bloom, E Schanzer, H Liao, SE Boyken, ... | 1 | 2020 |
| Potent and timed epigenetic repression of PD-1 in human T cells J Pearl, FD Urnov, JA Stamatoyannopoulos Blood 132, 3493, 2018 | 1 | 2018 |
| Nucleases For Genome Editing JA Stamatoyannopoulos, F Urnov, J Pearl, S Thomas US Patent App. 17/253,863, 2023 | | 2023 |
| A Genome Scale Transcriptional Regulatory Model of the Human Placenta A Paquette, K Ahuna, YM Hwang, J Pearl, H Liao, P Shannon, L Kadam, ... bioRxiv, 2022.09. 27.509541, 2022 | | 2022 |
| Characterizing Sex-Specific Differences in Placental Epigenome Using DNase-Sequencing Data. YM Hwang, AG Paquette, P Shannon, C Funk, J Pearl, H Liao, ... REPRODUCTIVE SCIENCES 28 (SUPPL 1), 169A-169A, 2021 | | 2021 |
| Characterizing Sex-specific Differences in Placental Epigenome Using DNase-sequencing Data. YM Hwang, AG Paquette, P Shannon, C Funk, J Pearl, H Liao, ... REPRODUCTIVE SCIENCES 27 (SUPPL 1), 165A-166A, 2020 | | 2020 |
