Christopher G Tate

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Gebhard F. X SchertlerHead of Biology and Chemistry Devision, PSI / ETHVerified email at psi.ch
richard hendersonScientist, MRC Laboratory of Molecular BiologyVerified email at mrc-lmb.cam.ac.uk
Francesca MagnaniDept. of Biology and Biotechnology, University of PaviaVerified email at unipv.it
Javier García-NafríaInstitute for Biocomputation and Physics of complex systemsVerified email at unizar.es
Nagarajan VaidehiBeckman Research Institute of City of HopeVerified email at coh.org
Fiona MarshallPresident Biomedical Research NovartisVerified email at novartis.com
Xavier DeupiSenior Scientist, Paul Scherrer InstituteVerified email at psi.ch
Miles CongreveIsomorphic LabsVerified email at isomorphiclabs.com
AJ VenkatakrishnanStanford UniversityVerified email at stanford.edu
M. Madan BabuMember and Endowed Chair, St Jude Children's Research Hospital, USAVerified email at stjude.org
Nathan RobertsonLabGeniusVerified email at labgeni.us
Jim F. WhiteNational Institutes of HealthVerified email at ninds.nih.gov
Carol V RobinsonProfessor of Chemistry University of OxfordVerified email at chem.ox.ac.uk
Supriyo BhattacharyaAssistant Research Professor, City of Hope National Medical CenterVerified email at coh.org
R. D. BlakelyFlorida Atlantic UniversityVerified email at health.fau.edu
Chris LangmeadMonash UniversityVerified email at monash.edu
Sang Bae LeeKIST 연구원Verified email at kist.re.kr
Jana HaaseLecturer School of Biomolecular and Biomedical Sciences, Conway Institute, University College DublinVerified email at ucd.ie
Shimon SchuldinerProfessor of Biochemistry, Hebrew UniversityVerified email at huji.ac.il
Michael BetenbaughJohns Hopkins University, Chemical and Biomolecular EngineeringVerified email at jhu.edu

Christopher G Tate

Programme Leader, MRC Laboratory of Molecular Biology, Cambridge

Verified email at mrc-lmb.cam.ac.uk

Membrane proteins


Title Sort by citations Sort by year Sort by title	Cited by Cited by	Year
Structure of a β₁-adrenergic G-protein-coupled receptor T Warne, MJ Serrano-Vega, JG Baker, R Moukhametzianov, PC Edwards, ... Nature 454 (7203), 486-491, 2008	1821	2008
Molecular signatures of G-protein-coupled receptors AJ Venkatakrishnan, X Deupi, G Lebon, CG Tate, GF Schertler, MM Babu Nature 494 (7436), 185-194, 2013	1714	2013
Agonist-bound adenosine A_2A receptor structures reveal common features of GPCR activation G Lebon, T Warne, PC Edwards, K Bennett, CJ Langmead, AGW Leslie, ... Nature 474 (7352), 521-525, 2011	1004	2011
The structural basis for agonist and partial agonist action on a β₁-adrenergic receptor T Warne, R Moukhametzianov, JG Baker, R Nehmé, PC Edwards, ... Nature 469 (7329), 241-244, 2011	746	2011
Structure of the adenosine A2A receptor in complex with ZM241385 and the xanthines XAC and caffeine AS Doré, N Robertson, JC Errey, I Ng, K Hollenstein, B Tehan, E Hurrell, ... Structure 19 (9), 1283-1293, 2011	623	2011
Structure of the agonist-bound neurotensin receptor JF White, N Noinaj, Y Shibata, J Love, B Kloss, F Xu, ... Nature 490 (7421), 508-513, 2012	571	2012
Conformational thermostabilization of the β1-adrenergic receptor in a detergent-resistant form MJ Serrano-Vega, F Magnani, Y Shibata, CG Tate Proceedings of the National Academy of Sciences 105 (3), 877-882, 2008	530	2008
Overcoming barriers to membrane protein structure determination RM Bill, PJF Henderson, S Iwata, ERS Kunji, H Michel, R Neutze, ... Nature biotechnology 29 (4), 335-340, 2011	485	2011
Structure of the adenosine A_2A receptor bound to an engineered G protein B Carpenter, R Nehmé, T Warne, AGW Leslie, CG Tate Nature 536 (7614), 104-107, 2016	460	2016
Universal allosteric mechanism for Gα activation by GPCRs T Flock, CNJ Ravarani, D Sun, AJ Venkatakrishnan, M Kayikci, CG Tate, ... Nature 524 (7564), 173-179, 2015	368	2015
Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region AJ Venkatakrishnan, X Deupi, G Lebon, FM Heydenreich, T Flock, ... Nature 536 (7617), 484-487, 2016	318	2016
Overexpression of mammalian integral membrane proteins for structural studies CG Tate FEBS letters 504 (3), 94-98, 2001	299	2001
Co-evolving stability and conformational homogeneity of the human adenosine A2a receptor F Magnani, Y Shibata, MJ Serrano-Vega, CG Tate Proceedings of the National Academy of Sciences 105 (31), 10744-10749, 2008	287	2008
Mini G protein probes for active G protein–coupled receptors (GPCRs) in live cells Q Wan, N Okashah, A Inoue, R Nehmé, B Carpenter, CG Tate, ... Journal of Biological Chemistry 293 (19), 7466-7473, 2018	280	2018
Impact of GPCR structures on drug discovery M Congreve, C de Graaf, NA Swain, CG Tate Cell 181 (1), 81-91, 2020	275	2020
Crystal structures of a stabilized β1-adrenoceptor bound to the biased agonists bucindolol and carvedilol T Warne, PC Edwards, AGW Leslie, CG Tate Structure 20 (5), 841-849, 2012	275	2012
PtdIns (4, 5) P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling HY Yen, KK Hoi, I Liko, G Hedger, MR Horrell, W Song, D Wu, P Heine, ... Nature 559 (7714), 423-427, 2018	251	2018
Cryo-EM structure of the adenosine A_2A receptor coupled to an engineered heterotrimeric G protein J García-Nafría, Y Lee, X Bai, B Carpenter, CG Tate elife 7, e35946, 2018	248	2018
Three-dimensional structure of the bacterial multidrug transporter EmrE shows it is an asymmetric homodimer I Ubarretxena-Belandia, JM Baldwin, S Schuldiner, CG Tate The EMBO journal 22 (23), 6175-6181, 2003	239	2003
Two distinct conformations of helix 6 observed in antagonist-bound structures of a β₁-adrenergic receptor R Moukhametzianov, T Warne, PC Edwards, MJ Serrano-Vega, ... Proceedings of the National Academy of Sciences 108 (20), 8228-8232, 2011	235	2011

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