| Comprehensive analysis of hypermutation in human cancer BB Campbell, N Light, D Fabrizio, M Zatzman, F Fuligni, R de Borja, ... Cell 171 (5), 1042-1056. e10, 2017 | 773 | 2017 |
| Clinical, radiologic, pathologic, and molecular characteristics of long-term survivors of diffuse intrinsic pontine glioma (DIPG): a collaborative report from the International … LM Hoffman, SEM Veldhuijzen van Zanten, N Colditz, J Baugh, B Chaney, ... Journal of clinical oncology 36 (19), 1963-1972, 2018 | 394 | 2018 |
| A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia S Shah, KA Schrader, E Waanders, AE Timms, J Vijai, C Miething, ... Nature genetics 45 (10), 1226-1231, 2013 | 373 | 2013 |
| Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer M Wong, C Mayoh, LMS Lau, DA Khuong-Quang, M Pinese, A Kumar, ... Nature medicine 26 (11), 1742-1753, 2020 | 305 | 2020 |
| Infant high-grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes M Clarke, A Mackay, B Ismer, JC Pickles, RG Tatevossian, S Newman, ... Cancer discovery 10 (7), 942-963, 2020 | 249 | 2020 |
| Frontiers in the treatment of glioblastoma: Past, present and emerging TI Janjua, P Rewatkar, A Ahmed-Cox, I Saeed, FM Mansfeld, ... Advanced drug delivery reviews 171, 108-138, 2021 | 209 | 2021 |
| Pre-clinical study of panobinostat in xenograft and genetically engineered murine diffuse intrinsic pontine glioma models T Hennika, G Hu, NG Olaciregui, KL Barton, A Ehteda, A Chitranjan, ... PloS one 12 (1), e0169485, 2017 | 175 | 2017 |
| Histone H3. 3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ... Cell 183 (6), 1617-1633. e22, 2020 | 146 | 2020 |
| Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma DR Carter, J Murray, BB Cheung, L Gamble, J Koach, J Tsang, S Sutton, ... Science translational medicine 7 (312), 312ra176-312ra176, 2015 | 142 | 2015 |
| Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins DS Ziegler, RD Wright, S Kesari, ME Lemieux, MA Tran, M Jain, L Zawel, ... The Journal of clinical investigation 118 (9), 3109-3122, 2008 | 135 | 2008 |
| Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study W Sun, J Malvar, R Sposto, A Verma, JJ Wilkes, R Dennis, K Heym, ... Leukemia 32 (11), 2316-2325, 2018 | 134 | 2018 |
| Efficacy and safety of larotrectinib in TRK fusion-positive primary central nervous system tumors F Doz, CM Van Tilburg, B Geoerger, M Højgaard, I Øra, V Boni, M Capra, ... Neuro-oncology 24 (6), 997-1007, 2022 | 131 | 2022 |
| Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma LD Gamble, S Purgato, J Murray, L Xiao, DMT Yu, KM Hanssen, ... Science Translational Medicine 11 (477), eaau1099, 2019 | 130 | 2019 |
| Therapeutic targeting of apoptosis pathways in cancer DS Ziegler, AL Kung Current Opinion in Oncology 20 (1), 97-103, 2008 | 126 | 2008 |
| Anti-apoptosis mechanisms in malignant gliomas DS Ziegler, AL Kung, MW Kieran Journal of Clinical Oncology 26 (3), 493-500, 2008 | 122 | 2008 |
| Brief report: potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma DS Ziegler, M Wong, C Mayoh, A Kumar, M Tsoli, E Mould, V Tyrrell, ... British Journal of Cancer 119 (6), 693-696, 2018 | 118 | 2018 |
| Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency A Das, S Sudhaman, D Morgenstern, A Coblentz, J Chung, SC Stone, ... Nature medicine 28 (1), 125-135, 2022 | 114 | 2022 |
| Pineoblastoma segregates into molecular sub-groups with distinct clinico-pathologic features: a Rare Brain Tumor Consortium registry study BK Li, A Vasiljevic, C Dufour, F Yao, BLB Ho, M Lu, EI Hwang, ... Acta neuropathologica 139, 223-241, 2020 | 107 | 2020 |
| Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas A Khan, LD Gamble, DH Upton, C Ung, DMT Yu, A Ehteda, R Pandher, ... Nature communications 12 (1), 971, 2021 | 105 | 2021 |
| Too many targets, not enough patients: rethinking neuroblastoma clinical trials JI Fletcher, DS Ziegler, TN Trahair, GM Marshall, M Haber, MD Norris Nature Reviews Cancer 18 (6), 389-400, 2018 | 101 | 2018 |
Michelle HaberProfessor and Executive Director, Children's Cancer InstituteVerified email at ccia.unsw.edu.au
