Genetic correction of sickle cell disease: insights using transgenic mouse models MJ Blouin, H Beauchemin, A Wright, M De Paepe, M Sorette, AM Bleau, ... Nature Medicine 6 (2), 177-182, 2000 | 80 | 2000 |
Growth factor independence 1b (gfi1b) is important for the maturation of erythroid cells and the regulation of embryonic globin expression L Vassen, H Beauchemin, W Lemsaddek, J Krongold, M Trudel, T Möröy PloS one 9 (5), e96636, 2014 | 46 | 2014 |
Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes P Shooshtarizadeh, A Helness, C Vadnais, N Brouwer, H Beauchemin, ... Nature Communications 10 (1), 1270, 2019 | 40 | 2019 |
Cell culture-induced aberrant methylation of the imprinted IG DMR in human lymphoblastoid cell lines A Saferali, E Grundberg, S Berlivet, H Beauchemin, L Morcos, ... Epigenetics 5 (1), 50-60, 2010 | 39 | 2010 |
Differential regulatory and compensatory responses in hematopoiesis/erythropoiesis in α-and β-globin hemizygous mice H Beauchemin, MJ Blouin, M Trudel Journal of Biological Chemistry 279 (19), 19471-19480, 2004 | 39 | 2004 |
Gfi1b controls integrin signaling-dependent cytoskeleton dynamics and organization in megakaryocytes H Beauchemin, P Shooshtarizadeh, C Vadnais, L Vassen, YD Pastore, ... Haematologica 102 (3), 484, 2017 | 25 | 2017 |
Multifaceted actions of GFI1 and GFI1B in hematopoietic stem cell self-renewal and lineage commitment H Beauchemin, T Möröy Frontiers in Genetics 11, 591099, 2020 | 22 | 2020 |
The common, autoimmunity-predisposing 620Arg> Trp variant of PTPN22 modulates macrophage function and morphology M Li, H Beauchemin, N Popovic, A Peterson, E d’Hennezel, CA Piccirillo, ... Journal of autoimmunity 79, 74-83, 2017 | 22 | 2017 |
Reduced expression but not deficiency of GFI1 causes a fatal myeloproliferative disease in mice J Fraszczak, C Vadnais, M Rashkovan, J Ross, H Beauchemin, R Chen, ... Leukemia 33 (1), 110-121, 2019 | 16 | 2019 |
BP1 is a negative modulator of definitive erythropoiesis MSEM Mpollo, M Beaudoin, PE Berg, H Beauchemin, V D'Agati, M Trudel Nucleic acids research 34 (18), 5232-5237, 2006 | 15 | 2006 |
Pancreatic islet cell phenotype and endocrine function throughout diabetes development in non-obese diabetic mice M Kornete, H Beauchemin, C Polychronakos, CA Piccirillo Autoimmunity 46 (4), 259-268, 2013 | 13 | 2013 |
Generation and characterization of human iPSC line MML-6838-Cl2 from mobilized peripheral blood derived megakaryoblasts M Hansen, E Varga, T Wüst, N Brouwer, H Beauchemin, C Mellink, ... Stem cell research 18, 26-28, 2017 | 11 | 2017 |
Evidence for a bigenic chromatin subdomain in regulation of the fetal-to-adult hemoglobin switch H Beauchemin, M Trudel Molecular and cellular biology, 2009 | 9 | 2009 |
The X-linked helicase DDX3X is required for lymphoid differentiation and MYC-driven lymphomagenesis M Lacroix, H Beauchemin, J Fraszczak, J Ross, P Shooshtarizadeh, ... Cancer Research 82 (17), 3172-3186, 2022 | 8 | 2022 |
Dominant negative Gfi1b mutations cause moderate thrombocytopenia and an impaired stress thrombopoiesis associated with mild erythropoietic abnormalities in mice H Beauchemin, P Shooshtharizadeh, J Pinder, G Dellaire, T Möröy haematologica 105 (10), 2457, 2020 | 7 | 2020 |
The RNA helicase DDX3 and its role in c-MYC driven germinal center-derived B-cell lymphoma M Lacroix, H Beauchemin, C Khandanpour, T Möröy Frontiers in Oncology 13, 1148936, 2023 | 6 | 2023 |
DDX3: a relevant therapeutic target for lymphoma? M Lacroix, H Beauchemin, T Möröy Expert Opinion on Therapeutic Targets 26 (12), 1037-1040, 2022 | 2 | 2022 |
Abstract LB559: The X-linked gene for the helicase DDX3X is required for lymphoid differentiation and MYC-driven lymphomagenesis M Lacroix, H Beauchemin, J Ross, J Fraszczak, P Shooshtarizadeh, ... Cancer Research 82 (12_Supplement), LB559-LB559, 2022 | | 2022 |
The X-linked gene for the helicase DDX3X is required for lymphoid differentiation and MYC-driven lymphomagenesis M Lacroix, H Beauchemin, J Ross, J Fraszczak, P Shooshtarizadeh, ... The Journal of Immunology 208 (1_Supplement), 47.05-47.05, 2022 | | 2022 |
Dominant-Negative GFI1B Mutations are Causal in Rare Inherited Platelet Disorders and Cause Defects in Stress Thrombopoiesis T Moroy, H Beauchemin Experimental Hematology 64, S88, 2018 | | 2018 |