Mutations of the BRAF gene in human cancer H Davies, GR Bignell, C Cox, P Stephens, S Edkins, S Clegg, J Teague, ... Nature 417 (6892), 949-954, 2002 | 12675 | 2002 |
Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease BS Paugh, C Qu, C Jones, Z Liu, M Adamowicz-Brice, J Zhang, DA Bax, ... Journal of clinical oncology 28 (18), 3061, 2010 | 706 | 2010 |
Diffuse brainstem glioma in children: critical review of clinical trials D Hargrave, U Bartels, E Bouffet The lancet oncology 7 (3), 241-248, 2006 | 683 | 2006 |
Challenges to curing primary brain tumours K Aldape, KM Brindle, L Chesler, R Chopra, A Gajjar, MR Gilbert, ... Nature reviews Clinical oncology 16 (8), 509-520, 2019 | 674 | 2019 |
The advantages of targeted protein degradation over inhibition: an RTK case study GM Burslem, BE Smith, AC Lai, S Jaime-Figueroa, DC McQuaid, ... Cell chemical biology 25 (1), 67-77. e3, 2018 | 528 | 2018 |
Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma KR Taylor, A Mackay, N Truffaux, YS Butterfield, O Morozova, C Philippe, ... Nature genetics 46 (5), 457-461, 2014 | 504 | 2014 |
Pediatric high-grade glioma: biologically and clinically in need of new thinking C Jones, MA Karajannis, DTW Jones, MW Kieran, M Monje, SJ Baker, ... Neuro-oncology 19 (2), 153-161, 2017 | 370 | 2017 |
Clinical, radiologic, pathologic, and molecular characteristics of long-term survivors of diffuse intrinsic pontine glioma (DIPG): a collaborative report from the International … LM Hoffman, SEM Veldhuijzen van Zanten, N Colditz, J Baugh, B Chaney, ... Journal of clinical oncology 36 (19), 1963-1972, 2018 | 328 | 2018 |
Histone H3. 3 mutations drive pediatric glioblastoma through upregulation of MYCN L Bjerke, A Mackay, M Nandhabalan, A Burford, A Jury, S Popov, DA Bax, ... Cancer discovery 3 (5), 512-519, 2013 | 326 | 2013 |
Visual outcomes in children with neurofibromatosis type 1–associated optic pathway glioma following chemotherapy: a multicenter retrospective analysis MJ Fisher, M Loguidice, DH Gutmann, R Listernick, RE Ferner, NJ Ullrich, ... Neuro-oncology 14 (6), 790-797, 2012 | 310 | 2012 |
Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy L Al-Olabi, S Polubothu, K Dowsett, KA Andrews, P Stadnik, AP Joseph, ... The Journal of clinical investigation 128 (4), 1496-1508, 2018 | 255 | 2018 |
Phase II study of weekly vinblastine in recurrent or refractory pediatric low-grade glioma E Bouffet, R Jakacki, S Goldman, D Hargrave, C Hawkins, M Shroff, ... Journal of clinical oncology 30 (12), 1358-1363, 2012 | 227 | 2012 |
Melanoma in congenital melanocytic naevi VA Kinsler, P O'hare, N Bulstrode, JE Calonje, WK Chong, D Hargrave, ... British Journal of Dermatology 176 (5), 1131-1143, 2017 | 225 | 2017 |
Paediatric and adult malignant glioma: close relatives or distant cousins? C Jones, L Perryman, D Hargrave Nature reviews Clinical oncology 9 (7), 400-413, 2012 | 215 | 2012 |
Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease RM Hill, S Kuijper, JC Lindsey, K Petrie, EC Schwalbe, K Barker, ... Cancer cell 27 (1), 72-84, 2015 | 212 | 2015 |
Infant high-grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes M Clarke, A Mackay, B Ismer, JC Pickles, RG Tatevossian, S Newman, ... Cancer discovery 10 (7), 942-963, 2020 | 206 | 2020 |
MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase–mediated HOX/stem cell gene signature N Gaspar, L Marshall, L Perryman, DA Bax, SE Little, M Viana-Pereira, ... Cancer research 70 (22), 9243-9252, 2010 | 202 | 2010 |
Nocturnal oxygen saturation and painful sickle cell crises in children DR Hargrave, A Wade, JPM Evans, DKM Hewes, FJ Kirkham Blood, The Journal of the American Society of Hematology 101 (3), 846-848, 2003 | 200 | 2003 |
Quality of health information on the Internet in pediatric neuro-oncology DR Hargrave, UA Hargrave, E Bouffet Neuro-oncology 8 (2), 175-182, 2006 | 191 | 2006 |
The COVID‐19 pandemic: a rapid global response for children with cancer from SIOP, COG, SIOP‐E, SIOP‐PODC, IPSO, PROS, CCI, and St Jude Global M Sullivan, E Bouffet, C Rodriguez‐Galindo, S Luna‐Fineman, MS Khan, ... Pediatric blood & cancer 67 (7), e28409, 2020 | 180 | 2020 |