PAX3–FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability BE Gryder, ME Yohe, HC Chou, X Zhang, J Marques, M Wachtel, ... Cancer Discovery 7 (8), 884-899, 2017 | 253 | 2017 |
Down-regulation of RNA editing in pediatric astrocytomas: ADAR2 editing activity inhibits cell migration and proliferation C Cenci, R Barzotti, F Galeano, S Corbelli, R Rota, L Massimi, C Di Rocco, ... Journal of Biological Chemistry 283 (11), 7251-7260, 2008 | 229 | 2008 |
Deregulated expression of miR-26a and Ezh2 in rhabdomyosarcoma R Ciarapica, G Russo, F Verginelli, L Raimondi, A Donfrancesco, R Rota, ... Cell Cycle 8 (1), 172-175, 2009 | 155 | 2009 |
Chemical genomics reveals histone deacetylases are required for core regulatory transcription BE Gryder, L Wu, GM Woldemichael, S Pomella, TR Quinn, PMC Park, ... Nature communications 10 (1), 3004, 2019 | 125 | 2019 |
Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma BE Gryder, S Pomella, C Sayers, XS Wu, Y Song, AM Chiarella, S Bagchi, ... Nature genetics 51 (12), 1714-1722, 2019 | 124 | 2019 |
Reduction of retinal albumin leakage by the antioxidant calcium dobesilate in streptozotocin-diabetic rats R Rota, C Chiavaroli, RP Garay, P Hannaert European Journal of Pharmacology 495 (2-3), 217-224, 2004 | 108 | 2004 |
Rhabdomyosarcoma: current challenges and their implications for developing therapies S Hettmer, Z Li, AN Billin, FG Barr, DDW Cornelison, AR Ehrlich, ... Cold Spring Harbor perspectives in medicine 4 (11), a025650, 2014 | 84 | 2014 |
Inhibition of Notch3 signalling induces rhabdomyosarcoma cell differentiation promoting p38 phosphorylation and p21Cip1 expression and hampers tumour cell growth in vitro and … L Raimondi, R Ciarapica, M De Salvo, F Verginelli, M Gueguen, C Martini, ... Cell Death & Differentiation 19 (5), 871-881, 2012 | 81 | 2012 |
MMSET is highly expressed and associated with aggressiveness in neuroblastoma HR Hudlebusch, J Skotte, E Santoni-Rugiu, ZG Zimling, MJ Lees, ... Cancer research 71 (12), 4226-4235, 2011 | 77 | 2011 |
Marked inhibition of retinal neovascularization in rats following soluble‐flt‐1 gene transfer R Rota, T Riccioni, M Zaccarini, S Lamartina, AD Gallo, A Fusco, I Kovesdi, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2004 | 76 | 2004 |
Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS R Ciarapica, E Carcarino, L Adesso, M De Salvo, G Bracaglia, ... BMC cancer 14, 1-15, 2014 | 74 | 2014 |
The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx) R Ciarapica, M De Salvo, E Carcarino, G Bracaglia, L Adesso, ... Oncogene 33 (32), 4173-4184, 2014 | 73 | 2014 |
Insights into pediatric rhabdomyosarcoma research: Challenges and goals ME Yohe, CM Heske, E Stewart, PC Adamson, N Ahmed, CR Antonescu, ... Pediatric blood & cancer 66 (10), e27869, 2019 | 71 | 2019 |
Helper‐dependent adenovirus for the gene therapy of proliferative retinopathies: stable gene transfer, regulated gene expression and therapeutic efficacy S Lamartina, M Cimino, G Roscilli, E Dammassa, D Lazzaro, R Rota, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2007 | 71 | 2007 |
Aberrant function of the C-terminal tail of HIST1H1E accelerates cellular senescence and causes premature aging E Flex, S Martinelli, A Van Dijck, A Ciolfi, S Cecchetti, E Coluzzi, ... The American Journal of Human Genetics 105 (3), 493-508, 2019 | 68 | 2019 |
Brain targeting by liposome–biomolecular corona boosts anticancer efficacy of temozolomide in glioblastoma cells A Arcella, S Palchetti, L Digiacomo, D Pozzi, AL Capriotti, L Frati, ... ACS chemical neuroscience 9 (12), 3166-3174, 2018 | 63 | 2018 |
Wild-type p53 gene transfer inhibits invasion and reduces matrix metalloproteinase-2 levels in p53-mutated human melanoma cells E Toschi, A Antonini, G Melillo, MC Capogrossi, R Rota Journal of investigative dermatology 114 (6), 1188-1194, 2000 | 60 | 2000 |
EZH2 Down-Regulation Exacerbates Lipid Accumulation and Inflammation in in Vitro and in Vivo NAFLD S Vella, D Gnani, A Crudele, S Ceccarelli, C De Stefanis, S Gaspari, ... International journal of molecular sciences 14 (12), 24154-24168, 2013 | 58 | 2013 |
MicroRNAs in rhabdomyosarcoma: pathogenetic implications and translational potentiality R Rota, R Ciarapica, A Giordano, L Miele, F Locatelli Molecular cancer 10, 1-14, 2011 | 56 | 2011 |
Focal adhesion kinase depletion reduces human hepatocellular carcinoma growth by repressing enhancer of zeste homolog 2 D Gnani, I Romito, S Artuso, M Chierici, C De Stefanis, N Panera, ... Cell Death & Differentiation 24 (5), 889-902, 2017 | 55 | 2017 |