| Mutations of the BRAF gene in human cancer H Davies, GR Bignell, C Cox, P Stephens, S Edkins, S Clegg, J Teague, ... Nature 417 (6892), 949-954, 2002 | 12933 | 2002 |
| Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... nature 500 (7463), 415-421, 2013 | 10270 | 2013 |
| Identification of the breast cancer susceptibility gene BRCA2 R Wooster, G Bignell, J Lancaster, S Swift, S Seal, J Mangion, N Collins, ... Nature 378 (6559), 789-792, 1995 | 4944 | 1995 |
| Patterns of somatic mutation in human cancer genomes C Greenman, P Stephens, R Smith, GL Dalgliesh, C Hunter, G Bignell, ... Nature 446 (7132), 153-158, 2007 | 3804 | 2007 |
| Massive genomic rearrangement acquired in a single catastrophic event during cancer development PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ... cell 144 (1), 27-40, 2011 | 2661 | 2011 |
| Systematic identification of genomic markers of drug sensitivity in cancer cells MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ... Nature 483 (7391), 570-575, 2012 | 2623 | 2012 |
| Mutational processes molding the genomes of 21 breast cancers S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ... Cell 149 (5), 979-993, 2012 | 2125 | 2012 |
| A serine/threonine kinase gene defective in Peutz–Jeghers syndrome A Hemminki, D Markie, I Tomlinson, E Avizienyte, S Roth, A Loukola, ... Nature 391 (6663), 184-187, 1998 | 2108 | 1998 |
| A comprehensive catalogue of somatic mutations from a human cancer genome ED Pleasance, RK Cheetham, PJ Stephens, DJ McBride, SJ Humphray, ... Nature 463 (7278), 191-196, 2010 | 2051 | 2010 |
| The landscape of cancer genes and mutational processes in breast cancer PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ... Nature 486 (7403), 400-404, 2012 | 1941 | 2012 |
| A landscape of pharmacogenomic interactions in cancer F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ... Cell 166 (3), 740-754, 2016 | 1857 | 2016 |
| The life history of 21 breast cancers S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ... Cell 149 (5), 994-1007, 2012 | 1597 | 2012 |
| BRAF and RAS mutations in human lung cancer and melanoma MS Brose, P Volpe, M Feldman, M Kumar, I Rishi, R Gerrero, E Einhorn, ... Cancer research 62 (23), 6997, 2002 | 1500 | 2002 |
| Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma I Varela, P Tarpey, K Raine, D Huang, CK Ong, P Stephens, H Davies, ... Nature 469 (7331), 539-542, 2011 | 1426 | 2011 |
| Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes GL Dalgliesh, K Furge, C Greenman, L Chen, G Bignell, A Butler, ... Nature 463 (7279), 360-363, 2010 | 1377 | 2010 |
| Heterogeneity of genomic evolution and mutational profiles in multiple myeloma N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ... Nature communications 5 (1), 2997, 2014 | 1001 | 2014 |
| Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing PJ Campbell, PJ Stephens, ED Pleasance, S O'Meara, H Li, T Santarius, ... Nature genetics 40 (6), 722-729, 2008 | 989 | 2008 |
| Intragenic ERBB2 kinase mutations in tumours P Stephens, C Hunter, G Bignell, S Edkins, H Davies, J Teague, ... Nature 431 (7008), 525-526, 2004 | 961 | 2004 |
| Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer G Van Haaften, GL Dalgliesh, H Davies, L Chen, G Bignell, C Greenman, ... Nature genetics 41 (5), 521-523, 2009 | 937 | 2009 |
| Identification of the familial cylindromatosis tumour-suppressor gene GR Bignell, W Warren, S Seal, M Takahashi, E Rapley, R Barfoot, ... Nature genetics 25 (2), 160-165, 2000 | 847 | 2000 |
Ludmil B. AlexandrovProfessor, University of California San DiegoVerified email at ucsd.edu
