Human metabolic individuality in biomedical and pharmaceutical research K Suhre, SY Shin, AK Petersen, RP Mohney, D Meredith, B Wägele, ... Nature 477 (7362), 54-60, 2011 | 1120 | 2011 |
Connecting genetic risk to disease end points through the human blood plasma proteome K Suhre, M Arnold, AM Bhagwat, RJ Cotton, R Engelke, J Raffler, ... Nature communications 8 (1), 14357, 2017 | 679 | 2017 |
The dynamic range of the human metabolome revealed by challenges S Krug, G Kastenmüller, F Stückler, MJ Rist, T Skurk, M Sailer, J Raffler, ... The FASEB Journal 26 (6), 2607-2619, 2012 | 366 | 2012 |
SNiPA: an interactive, genetic variant-centered annotation browser M Arnold, J Raffler, A Pfeufer, K Suhre, G Kastenmüller Bioinformatics 31 (8), 1334-1336, 2015 | 335 | 2015 |
Mapping the proteo-genomic convergence of human diseases M Pietzner, E Wheeler, J Carrasco-Zanini, A Cortes, M Koprulu, ... Science 374 (6569), eabj1541, 2021 | 314 | 2021 |
A genome-wide association study of metabolic traits in human urine K Suhre, H Wallaschofski, J Raffler, N Friedrich, R Haring, K Michael, ... Nature genetics 43 (6), 565-569, 2011 | 280 | 2011 |
Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies KT Do, S Wahl, J Raffler, S Molnos, M Laimighofer, J Adamski, K Suhre, ... Metabolomics 14, 1-18, 2018 | 193 | 2018 |
A cross-platform approach identifies genetic regulators of human metabolism and health LA Lotta, M Pietzner, ID Stewart, LBL Wittemans, C Li, R Bonelli, J Raffler, ... Nature genetics 53 (1), 54-64, 2021 | 152 | 2021 |
Genetics of human metabolism: an update G Kastenmüller, J Raffler, C Gieger, K Suhre Human molecular genetics 24 (R1), R93-R101, 2015 | 141 | 2015 |
Plasma metabolites to profile pathways in noncommunicable disease multimorbidity M Pietzner, ID Stewart, J Raffler, KT Khaw, GA Michelotti, G Kastenmüller, ... Nature medicine 27 (3), 471-479, 2021 | 138 | 2021 |
Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans P Schlosser, Y Li, P Sekula, J Raffler, F Grundner-Culemann, M Pietzner, ... Nature genetics 52 (2), 167-176, 2020 | 118 | 2020 |
Genetic architecture of host proteins involved in SARS-CoV-2 infection M Pietzner, E Wheeler, J Carrasco-Zanini, J Raffler, ND Kerrison, ... Nature communications 11 (1), 6397, 2020 | 104 | 2020 |
Genome-wide association study with targeted and non-targeted NMR metabolomics identifies 15 novel loci of urinary human metabolic individuality J Raffler, N Friedrich, M Arnold, T Kacprowski, R Rueedi, E Altmaier, ... PLoS genetics 11 (9), e1005487, 2015 | 101 | 2015 |
Rare and common genetic determinants of metabolic individuality and their effects on human health P Surendran, ID Stewart, VPW Au Yeung, M Pietzner, J Raffler, ... Nature Medicine 28 (11), 2321-2332, 2022 | 82 | 2022 |
Biochemical insights from population studies with genetics and metabolomics K Suhre, J Raffler, G Kastenmueller Archives of biochemistry and biophysics 589, 168-176, 2016 | 70 | 2016 |
Fine mapping and functional analysis reveal a role of SLC22A1 in acylcarnitine transport HI Kim, J Raffler, W Lu, JJ Lee, D Abbey, D Saleheen, JD Rabinowitz, ... The American Journal of Human Genetics 101 (4), 489-502, 2017 | 59 | 2017 |
A predictive model for progression of CKD to kidney failure based on routine laboratory tests HU Zacharias, M Altenbuchinger, UT Schultheiss, J Raffler, F Kotsis, ... American Journal of Kidney Diseases 79 (2), 217-230. e1, 2022 | 48 | 2022 |
Genetic associations with lipoprotein subfractions provide information on their biological nature AK Petersen, K Stark, MD Musameh, CP Nelson, W Römisch-Margl, ... Human molecular genetics 21 (6), 1433-1443, 2012 | 45 | 2012 |
Genome-wide association studies of metabolite concentrations (mGWAS): relevance for nephrology A Köttgen, J Raffler, P Sekula, G Kastenmüller Seminars in nephrology 38 (2), 151-174, 2018 | 36 | 2018 |
HitPickV2: a web server to predict targets of chemical compounds S Hamad, G Adornetto, JJ Naveja, A Chavan Ravindranath, J Raffler, ... Bioinformatics 35 (7), 1239-1240, 2019 | 32 | 2019 |