A cyclic oligonucleotide signaling pathway in type III CRISPR-Cas systems M Kazlauskiene, G Kostiuk, Č Venclovas, G Tamulaitis, V Siksnys Science 357 (6351), 605-609, 2017 | 453 | 2017 |
Programmable RNA shredding by the type III-A CRISPR-Cas system of Streptococcus thermophilus G Tamulaitis, M Kazlauskiene, E Manakova, Č Venclovas, AO Nwokeoji, ... Molecular cell 56 (4), 506-517, 2014 | 337 | 2014 |
Spatiotemporal control of type III-A CRISPR-Cas immunity: coupling DNA degradation with the target RNA recognition M Kazlauskiene, G Tamulaitis, G Kostiuk, Č Venclovas, V Siksnys Molecular cell 62 (2), 295-306, 2016 | 279 | 2016 |
Type III CRISPR-Cas immunity: major differences brushed aside G Tamulaitis, Č Venclovas, V Siksnys Trends in microbiology 25 (1), 49-61, 2017 | 147 | 2017 |
Single-Molecule Dynamics of the DNA−EcoRII Protein Complexes Revealed with High-Speed Atomic Force Microscopy JL Gilmore, Y Suzuki, G Tamulaitis, V Siksnys, K Takeyasu, ... Biochemistry 48 (44), 10492-10498, 2009 | 100 | 2009 |
Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease M Bochtler, RH Szczepanowski, G Tamulaitis, S Grazulis, H Czapinska, ... The EMBO Journal 25 (10), 2219-2229, 2006 | 82 | 2006 |
The recognition domain of the methyl-specific endonuclease McrBC flips out 5-methylcytosine R Sukackaite, S Grazulis, G Tamulaitis, V Siksnys Nucleic acids research 40 (15), 7552-7562, 2012 | 64 | 2012 |
Direct visualization of the EcoRII− DNA triple synaptic complex by atomic force microscopy LS Shlyakhtenko, J Gilmore, A Portillo, G Tamulaitis, V Siksnys, ... Biochemistry 46 (39), 11128-11136, 2007 | 53 | 2007 |
Alternative arrangements of catalytic residues at the active sites of restriction enzymes G Tamulaitis, AS Solonin, V Siksnys FEBS letters 518 (1-3), 17-22, 2002 | 52 | 2002 |
Nucleotide flipping by restriction enzymes analyzed by 2-aminopurine steady-state fluorescence G Tamulaitis, M Zaremba, RH Szczepanowski, M Bochtler, V Siksnys Nucleic acids research 35 (14), 4792-4799, 2007 | 50 | 2007 |
Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically M Kaus-Drobek, H Czapinska, M Sokołowska, G Tamulaitis, ... Nucleic acids research 35 (6), 2035-2046, 2007 | 49 | 2007 |
Monomeric restriction endonuclease BcnI in the apo form and in an asymmetric complex with target DNA M Sokolowska, M Kaus-Drobek, H Czapinska, G Tamulaitis, ... Journal of molecular biology 369 (3), 722-734, 2007 | 47 | 2007 |
Central base pair flipping and discrimination by PspGI RH Szczepanowski, MA Carpenter, H Czapinska, M Zaremba, ... Nucleic acids research 36 (19), 6109-6117, 2008 | 43 | 2008 |
Type III-A CRISPR-associated protein Csm6 degrades cyclic hexa-adenylate activator using both CARF and HEPN domains D Smalakyte, M Kazlauskiene, J F. Havelund, A Rukšėnaitė, A Rimaite, ... Nucleic acids research 48 (16), 9204-9217, 2020 | 41 | 2020 |
Simultaneous binding of three recognition sites is necessary for a concerted plasmid DNA cleavage by EcoRII restriction endonuclease G Tamulaitis, G Sasnauskas, M Mucke, V Siksnys Journal of molecular biology 358 (2), 406-419, 2006 | 37 | 2006 |
Biochemical and mutational analysis of EcoRII functional domains reveals evolutionary links between restriction enzymes G Tamulaitis, M Mucke, V Siksnys FEBS letters 580 (6), 1665-1671, 2006 | 37 | 2006 |
Genetic dissection of the type III-A CRISPR-Cas system csm complex reveals roles of individual subunits I Mogila, M Kazlauskiene, S Valinskyte, G Tamulaitiene, G Tamulaitis, ... Cell reports 26 (10), 2753-2765. e4, 2019 | 34 | 2019 |
Tetrameric restriction enzymes: expansion to the GIY-YIG nuclease family G Gasiunas, G Sasnauskas, G Tamulaitis, C Urbanke, D Razaniene, ... Nucleic acids research 36 (3), 938-949, 2008 | 34 | 2008 |
DNA synapsis through transient tetramerization triggers cleavage by Ecl18kI restriction enzyme M Zaremba, A Owsicka, G Tamulaitis, G Sasnauskas, LS Shlyakhtenko, ... Nucleic acids research 38 (20), 7142-7154, 2010 | 32 | 2010 |
Time-resolved fluorescence studies of nucleotide flipping by restriction enzymes RK Neely, G Tamulaitis, K Chen, M Kubala, V Siksnys, AC Jones Nucleic Acids Research 37 (20), 6859-6870, 2009 | 28 | 2009 |