Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ... Nature methods 16 (7), 595-602, 2019 | 526 | 2019 |
Stepwise protein folding at near amino acid resolution by hydrogen exchange and mass spectrometry W Hu, BT Walters, ZY Kan, L Mayne, LE Rosen, S Marqusee, ... Proceedings of the National Academy of Sciences 110 (19), 7684-7689, 2013 | 189 | 2013 |
Minimizing back exchange in the hydrogen exchange-mass spectrometry experiment BT Walters, A Ricciuti, L Mayne, SW Englander Journal of the American Society for Mass Spectrometry 23 (12), 2132-2139, 2012 | 178 | 2012 |
Protein hydrogen exchange at residue resolution by proteolytic fragmentation mass spectrometry analysis ZY Kan, BT Walters, L Mayne, SW Englander Proceedings of the National Academy of Sciences 110 (41), 16438-16443, 2013 | 153 | 2013 |
Many overlapping peptides for protein hydrogen exchange experiments by the fragment separation-mass spectrometry method L Mayne, ZY Kan, P Sevugan Chetty, A Ricciuti, BT Walters, ... Journal of the American Society for Mass Spectrometry 22 (11), 2011 | 126 | 2011 |
Folding of a large protein at high structural resolution BT Walters, L Mayne, JR Hinshaw, TR Sosnick, SW Englander Proceedings of the National Academy of Sciences 110 (47), 18898-18903, 2013 | 105 | 2013 |
An Efficient Organic Solvent Based Extraction Method for the Proteomic Analysis of Arabidopsis Plasma Membranes SK Mitra, BT Walters, SD Clouse, MB Goshe Journal of proteome research 8 (6), 2752-2767, 2009 | 94 | 2009 |
An allosteric anti-tryptase antibody for the treatment of mast cell-mediated severe asthma HR Maun, JK Jackman, DF Choy, KM Loyet, TL Staton, G Jia, A Dressen, ... Cell 179 (2), 417-431. e19, 2019 | 88 | 2019 |
Mutational landscape of antibody variable domains reveals a switch modulating the interdomain conformational dynamics and antigen binding P Koenig, CV Lee, BT Walters, V Janakiraman, J Stinson, TW Patapoff, ... Proceedings of the National Academy of Sciences 114 (4), E486-E495, 2017 | 87 | 2017 |
Interlaboratory comparison of hydrogen–deuterium exchange mass spectrometry measurements of the Fab fragment of NISTmAb JW Hudgens, ES Gallagher, I Karageorgos, KW Anderson, JJ Filliben, ... Analytical chemistry 91 (11), 7336-7345, 2019 | 52 | 2019 |
Solid-state hydrogen–deuterium exchange mass spectrometry: correlation of deuterium uptake and long-term stability of lyophilized monoclonal antibody formulations BS Moorthy, IE Zarraga, L Kumar, BT Walters, P Goldbach, EM Topp, ... Molecular pharmaceutics 15 (1), 1-11, 2018 | 46 | 2018 |
Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation MJ Holliday, A Witt, A Rodríguez Gama, BT Walters, CP Arthur, ... Nature Communications 10 (1), 3070, 2019 | 39 | 2019 |
Conformational destabilization of immunoglobulin G increases the low pH binding affinity with the neonatal Fc receptor BT Walters, PF Jensen, V Larraillet, K Lin, T Patapoff, T Schlothauer, ... Journal of Biological Chemistry 291 (4), 1817-1825, 2016 | 39 | 2016 |
Multiscale coarse-grained approach to investigate self-association of antibodies S Izadi, TW Patapoff, BT Walters Biophysical journal 118 (11), 2741-2754, 2020 | 32 | 2020 |
Dissecting the molecular basis of high viscosity of monospecific and bispecific IgG antibodies C Tilegenova, S Izadi, J Yin, CS Huang, J Wu, D Ellerman, SG Hymowitz, ... MAbs 12 (1), 1692764, 2020 | 31 | 2020 |
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands E Ferri, A Le Thomas, HA Wallweber, ES Day, BT Walters, SE Kaufman, ... Nature communications 11 (1), 6387, 2020 | 26 | 2020 |
Empirical method to accurately determine peptide-averaged protection factors from hydrogen exchange MS data BT Walters Analytical chemistry 89 (2), 1049-1053, 2017 | 18 | 2017 |
Bivalent antibody pliers inhibit β-tryptase by an allosteric mechanism dependent on the IgG hinge HR Maun, R Vij, BT Walters, A Morando, JK Jackman, P Wu, A Estevez, ... Nature Communications 11 (1), 6435, 2020 | 16 | 2020 |
Structure-based correlation of light-induced histidine reactivity in a model protein M Lei, T Carcelen, BT Walters, C Zamiri, C Quan, Y Hu, J Nishihara, H Yip, ... Analytical chemistry 89 (13), 7225-7231, 2017 | 14 | 2017 |
High-Throughput Kinetic Characterization of Irreversible Covalent Inhibitors of KRASG12C by Intact Protein MS and Targeted MRM KS Li, JG Quinn, MJ Saabye, JFS Guerrero, J Nonomiya, Q Lian, ... Analytical Chemistry 94 (2), 1230-1239, 2022 | 11 | 2022 |