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Derren Heyes
Derren Heyes
Manchester Institute of Biotechnology, University of Manchester
Verified email at manchester.ac.uk
Title
Cited by
Cited by
Year
Making light work of enzyme catalysis: protochlorophyllide oxidoreductase
DJ Heyes, CN Hunter
Trends in biochemical sciences 30 (11), 642-649, 2005
1682005
Conformational changes in an ultrafast light-driven enzyme determine catalytic activity
OA Sytina, DJ Heyes, CN Hunter, MT Alexandre, IHM Van Stokkum, ...
Nature 456 (7224), 1001-1004, 2008
1382008
Structural basis of kynurenine 3-monooxygenase inhibition
M Amaral, C Levy, DJ Heyes, P Lafite, TF Outeiro, F Giorgini, D Leys, ...
Nature 496 (7445), 382-385, 2013
1202013
Enzymology below 200 K: the kinetics and thermodynamics of the photochemistry catalyzed by protochlorophyllide oxidoreductase
DJ Heyes, AV Ruban, HM Wilks, CN Hunter
Proceedings of the National Academy of Sciences 99 (17), 11145-11150, 2002
1022002
Nuclear quantum tunneling in the light-activated enzyme protochlorophyllide oxidoreductase
DJ Heyes, M Sakuma, SP de Visser, NS Scrutton
Journal of Biological Chemistry 284 (6), 3762-3767, 2009
892009
Ultrafast enzymatic reaction dynamics in protochlorophyllide oxidoreductase
DJ Heyes, CN Hunter, IHM van Stokkum, R Van Grondelle, ML Groot
Nature Structural & Molecular Biology 10 (6), 491-492, 2003
822003
Protochlorophyllide oxidoreductase:“dark” reactions of a light-driven enzyme
DJ Heyes, AV Ruban, CN Hunter
Biochemistry 42 (2), 523-528, 2003
692003
Catalytic mechanism of cofactor-free dioxygenases and how they circumvent spin-forbidden oxygenation of their substrates
A Hernández-Ortega, MG Quesne, S Bui, DJ Heyes, RA Steiner, ...
Journal of the American Chemical Society 137 (23), 7474-7487, 2015
672015
Proton-Coupled Electron Transfer in the Catalytic Cycle of Alcaligenes xylosoxidans Copper-Dependent Nitrite Reductase
NGH Leferink, C Han, SV Antonyuk, DJ Heyes, SEJ Rigby, MA Hough, ...
Biochemistry 50 (19), 4121-4131, 2011
672011
The first catalytic step of the light-driven enzyme protochlorophyllide oxidoreductase proceeds via a charge transfer complex
DJ Heyes, P Heathcote, SEJ Rigby, MA Palacios, R van Grondelle, ...
Journal of Biological Chemistry 281 (37), 26847-26853, 2006
622006
Rapid P450 heme iron reduction by laser photoexcitation of Mycobacterium tuberculosis CYP121 and CYP51B1: analysis of CO complexation reactions and reversibility of the P450 …
AJ Dunford, KJ McLean, M Sabri, HE Seward, DJ Heyes, NS Scrutton, ...
Journal of Biological Chemistry 282 (34), 24816-24824, 2007
612007
Identification and characterization of the product release steps within the catalytic cycle of protochlorophyllide oxidoreductase
DJ Heyes, CN Hunter
Biochemistry 43 (25), 8265-8271, 2004
572004
NADPH: protochlorophyllide oxidoreductase from Synechocystis: overexpression, purification and preliminary characterisation
DJ Heyes, GEM Martin, RJ Reid, CN Hunter, HM Wilks
FEBS letters 483 (1), 47-51, 2000
562000
Molecular basis of halorespiration control by CprK, a CRP‐FNR type transcriptional regulator
C Levy, K Pike, DJ Heyes, MG Joyce, K Gabor, H Smidt, J Van Der Oost, ...
Molecular microbiology 70 (1), 151-167, 2008
552008
Demonstration of proton-coupled electron transfer in the copper-containing nitrite reductases
S Brenner, DJ Heyes, S Hay, MA Hough, RR Eady, SS Hasnain, ...
Journal of Biological Chemistry 284 (38), 25973-25983, 2009
512009
Enzymatic carboxylation of 2-furoic acid yields 2, 5-furandicarboxylic acid (FDCA)
KAP Payne, SA Marshall, K Fisher, MJ Cliff, DM Cannas, C Yan, ...
ACS catalysis 9 (4), 2854-2865, 2019
492019
Light-driven biocatalytic reduction of α, β-unsaturated compounds by ene reductases employing transition metal complexes as photosensitizers
MK Peers, HS Toogood, DJ Heyes, D Mansell, BJ Coe, NS Scrutton
Catalysis science & technology 6 (1), 169-177, 2016
462016
Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis
S Zhang, DJ Heyes, L Feng, W Sun, LO Johannissen, H Liu, CW Levy, ...
Nature 574 (7780), 722-725, 2019
442019
Protochlorophyllide excited-state dynamics in organic solvents studied by time-resolved visible and mid-infrared spectroscopy
OA Sytina, IHM Van Stokkum, DJ Heyes, CN Hunter, R Van Grondelle, ...
The Journal of Physical Chemistry B 114 (12), 4335-4344, 2010
432010
Excited state dynamics and catalytic mechanism of the light-driven enzyme protochlorophyllide oxidoreductase
NS Scrutton, ML Groot, DJ Heyes
Physical Chemistry Chemical Physics 14 (25), 8818-8824, 2012
422012
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