Nicholas Kennedy
Nicholas Kennedy
Consultant Gastroenterologist and Honorary Clinical Senior Lecturer, University of Exeter
Verified email at exeter.ac.uk
TitleCited byYear
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
I Cleynen, G Boucher, L Jostins, LP Schumm, S Zeissig, T Ahmad, ...
The Lancet 387 (10014), 156-167, 2016
3562016
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
KM de Lange, L Moutsianas, JC Lee, CA Lamb, Y Luo, NA Kennedy, ...
Nature genetics 49 (2), 256, 2017
2312017
Beyond gene discovery in inflammatory bowel disease: the emerging role of epigenetics
NT Ventham, NA Kennedy, ER Nimmo, J Satsangi
Gastroenterology 145 (2), 293-308, 2013
2022013
Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway
JC Lee, M Espéli, CA Anderson, MA Linterman, JM Pocock, NJ Williams, ...
Cell 155 (1), 57-69, 2013
1712013
The impact of different DNA extraction kits and laboratories upon the assessment of human gut microbiota composition by 16S rRNA gene sequencing
NA Kennedy, AW Walker, SH Berry, SH Duncan, FM Farquarson, P Louis, ...
PloS one 9 (2), e88982, 2014
1642014
High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ...
Nature genetics 47 (2), 172, 2015
1612015
Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway
ER Nimmo, JG Prendergast, MC Aldhous, NA Kennedy, P Henderson, ...
Inflammatory bowel diseases 18 (5), 889-899, 2011
1272011
MicroRNAs: new players in IBD
R Kalla, NT Ventham, NA Kennedy, JF Quintana, ER Nimmo, AH Buck, ...
Gut 64 (3), 504-513, 2015
1202015
The diagnostic accuracy of fecal calprotectin during the investigation of suspected pediatric inflammatory bowel disease
P Henderson, A Casey, SJ Lawrence, NA Kennedy, K Kingstone, ...
The American journal of gastroenterology 107 (6), 941, 2012
1122012
Systematic review of effects of withdrawal of immunomodulators or biologic agents from patients with inflammatory bowel disease
J Torres, RK Boyapati, NA Kennedy, E Louis, JF Colombel, J Satsangi
Gastroenterology 149 (7), 1716-1730, 2015
1012015
Inflammatory bowel disease associates with proinflammatory potential of the immunoglobulin G glycome
I Trbojević Akmačić, NT Ventham, E Theodoratou, F Vučković, ...
Inflammatory bowel diseases 21 (6), 1237-1247, 2015
942015
Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7
Y Luo, KM de Lange, L Jostins, L Moutsianas, J Randall, NA Kennedy, ...
Nature genetics 49 (2), 186, 2017
722017
The role of glycosylation in IBD
E Theodoratou, H Campbell, NT Ventham, D Kolarich, M Pučić-Baković, ...
Nature reviews Gastroenterology & hepatology 11 (10), 588, 2014
692014
Two-stage genome-wide methylation profiling in childhood-onset Crohn's disease implicates epigenetic alterations at the VMP1/MIR21 and HLA loci
AT Adams, NA Kennedy, R Hansen, NT Ventham, KR O'Leary, ...
Inflammatory bowel diseases 20 (10), 1784-1793, 2014
592014
Dietary manipulation of oncogenic microRNA expression in human rectal mucosa: a randomized trial
KJ Humphreys, MA Conlon, GP Young, DL Topping, Y Hu, JM Winter, ...
Cancer prevention research 7 (8), 786-795, 2014
562014
Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease
NT Ventham, NA Kennedy, AT Adams, R Kalla, S Heath, KR O'leary, ...
Nature communications 7, 13507, 2016
522016
A trial of mercaptopurine is a safe strategy in patients with inflammatory bowel disease intolerant to azathioprine: an observational study, systematic review and meta‐analysis
NA Kennedy, E Rhatigan, IDR Arnott, CL Noble, AG Shand, J Satsangi, ...
Alimentary pharmacology & therapeutics 38 (10), 1255-1266, 2013
492013
Thiopurine withdrawal during sustained clinical remission in inflammatory bowel disease: relapse and recapture rates, with predictive factors in 237 patients
NA Kennedy, R Kalla, B Warner, CJ Gambles, R Musy, S Reynolds, ...
Alimentary pharmacology & therapeutics 40 (11-12), 1313-1323, 2014
452014
Mercaptopurine versus placebo to prevent recurrence of Crohn's disease after surgical resection (TOPPIC): a multicentre, double-blind, randomised controlled trial
C Mowat, I Arnott, A Cahill, M Smith, T Ahmad, S Subramanian, S Travis, ...
The Lancet Gastroenterology & Hepatology 1 (4), 273-282, 2016
442016
Clinical utility and diagnostic accuracy of faecal calprotectin for IBD at first presentation to gastroenterology services in adults aged 16–50 years
NA Kennedy, A Clark, A Walkden, JCW Chang, F Fascí-Spurio, M Muscat, ...
Journal of Crohn's and Colitis 9 (1), 41-49, 2014
412014
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Articles 1–20