Follow
Sofie Lautrup
Sofie Lautrup
Post-doc Fellow, University of Oslo
Verified email at medisin.uio.no
Title
Cited by
Cited by
Year
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease
EF Fang, Y Hou, K Palikaras, BA Adriaanse, JS Kerr, B Yang, S Lautrup, ...
Nature neuroscience 22 (3), 401-412, 2019
11232019
NAD+ in brain aging and neurodegenerative disorders
S Lautrup, DA Sinclair, MP Mattson, EF Fang
Cell metabolism 30 (4), 630-655, 2019
4692019
NAD+ in aging: molecular mechanisms and translational implications
EF Fang, S Lautrup, Y Hou, TG Demarest, DL Croteau, MP Mattson, ...
Trends in molecular medicine 23 (10), 899-916, 2017
4282017
NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
Y Hou, S Lautrup, S Cordonnier, Y Wang, DL Croteau, E Zavala, Y Zhang, ...
Proceedings of the National Academy of Sciences 115 (8), E1876-E1885, 2018
3942018
Mitophagy in neurodegeneration and aging
EM Fivenson, S Lautrup, N Sun, M Scheibye-Knudsen, T Stevnsner, ...
Neurochemistry international 109, 202-209, 2017
3322017
Mitophagy and neuroprotection
G Lou, K Palikaras, S Lautrup, M Scheibye-Knudsen, N Tavernarakis, ...
Trends in molecular medicine 26 (1), 8-20, 2020
2792020
NAD+ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer’s disease via cGAS–STING
Y Hou, Y Wei, S Lautrup, B Yang, Y Wang, S Cordonnier, MP Mattson, ...
Proceedings of the National Academy of Sciences 118 (37), e2011226118, 2021
2032021
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
EF Fang, Y Hou, S Lautrup, MB Jensen, B Yang, T SenGupta, D Caponio, ...
Nature communications 10 (1), 5284, 2019
1872019
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary
T Schmauck-Medina, A Molière, S Lautrup, J Zhang, S Chlopicki, ...
Aging (Albany NY) 14 (16), 6829, 2022
1482022
Amelioration of Alzheimer’s disease pathology by mitophagy inducers identified via machine learning and a cross-species workflow
C Xie, XX Zhuang, Z Niu, R Ai, S Lautrup, S Zheng, Y Jiang, R Han, ...
Nature Biomedical Engineering 6 (1), 76-93, 2022
1302022
Microglial mitophagy mitigates neuroinflammation in Alzheimer's disease
S Lautrup, G Lou, Y Aman, H Nilsen, J Tao, EF Fang
Neurochemistry International 129, 104469, 2019
862019
Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing
BC Gilmour, R Gudmundsrud, J Frank, A Hov, S Lautrup, Y Aman, ...
Mechanisms of Ageing and Development 186, 111208, 2020
362020
The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications
Y Aman, J Frank, SH Lautrup, A Matysek, Z Niu, G Yang, L Shi, ...
Mechanisms of ageing and development 185, 111194, 2020
362020
Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases
S Lautrup, D Caponio, HH Cheung, C Piccoli, T Stevnsner, WY Chan, ...
Biogerontology 20, 255-269, 2019
302019
DNA damage-induced neurodegeneration in accelerated ageing and Alzheimer’s disease
H Wang, S Lautrup, D Caponio, J Zhang, EF Fang
International Journal of Molecular Sciences 22 (13), 6748, 2021
272021
Two Cockayne Syndrome patients with a novel splice site mutation–clinical and metabolic analyses
I Sanchez-Roman, S Lautrup, MD Aamann, EG Neilan, JR Østergaard, ...
Mechanisms of Ageing and Development 175, 7-16, 2018
112018
WRN promotes bone development and growth by unwinding SHOX-G-quadruplexes via its helicase activity in Werner Syndrome
Y Tian, W Wang, S Lautrup, H Zhao, X Li, PWN Law, ND Dinh, EF Fang, ...
Nature communications 13 (1), 5456, 2022
92022
Crosstalk among DNA damage, mitochondrial dysfunction, impaired mitophagy, stem cell attrition, and senescence in the accelerated ageing disorder Werner syndrome
R Gudmundsrud, TH Skjånes, BC Gilmour, D Caponio, S Lautrup, ...
Cytogenetic and Genome Research 161 (6-7), 297-304, 2021
82021
A comprehensive AI‐driven analysis of large‐scale omic datasets reveals novel dual‐purpose targets for the treatment of cancer and aging
FW Pun, GHD Leung, HW Leung, J Rice, T Schmauck‐Medina, S Lautrup, ...
Aging Cell 22 (12), e14017, 2023
52023
Roles of NAD+ in Health and Aging
S Lautrup, Y Hou, EF Fang, VA Bohr
Cold Spring Harbor Perspectives in Medicine 14 (1), a041193, 2024
22024
The system can't perform the operation now. Try again later.
Articles 1–20