| The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress JR Morris, C Boutell, M Keppler, R Densham, D Weekes, A Alamshah, ... Nature 462 (7275), 886-890, 2009 | 529 | 2009 |
| The proteasomal de‐ubiquitinating enzyme POH1 promotes the double‐strand DNA break response LR Butler, RM Densham, J Jia, AJ Garvin, HR Stone, V Shah, D Weekes, ... The EMBO journal 31 (19), 3918-3934, 2012 | 159 | 2012 |
| Genomic complexity profiling reveals that HORMAD1 overexpression contributes to homologous recombination deficiency in triple-negative breast cancers. Cancer Discov. 2015; 5 (5 … J Watkins, D Weekes, V Shah, P Gazinska, S Joshi, B Sidhu, C Gillett, ... CD-14-1092, 0 | 120* | |
| The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair AJ Garvin, RM Densham, SA Blair‐Reid, KM Pratt, HR Stone, D Weekes, ... EMBO reports 14 (11), 975-983, 2013 | 109 | 2013 |
| The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment LJ Monteiro, P Khongkow, M Kongsema, JR Morris, C Man, D Weekes, ... Oncogene 32 (39), 4634-4645, 2013 | 107 | 2013 |
| Regulation of osteosarcoma cell lung metastasis by the c-Fos/AP-1 target FGFR1 D Weekes, TG Kashima, C Zandueta, N Perurena, DP Thomas, A Sunters, ... Oncogene 35 (22), 2852-2861, 2016 | 85 | 2016 |
| The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin DB Krastev, S Li, Y Sun, AJ Wicks, G Hoslett, D Weekes, LM Badder, ... Nature cell biology 24 (1), 62-73, 2022 | 77 | 2022 |
| Selective ablation of retinoblastoma protein function by the RET finger protein M Krützfeldt, M Ellis, DB Weekes, JJ Bull, M Eilers, MM Vivanco, ... Molecular cell 18 (2), 213-224, 2005 | 66 | 2005 |
| Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer N Patel, D Weekes, K Drosopoulos, P Gazinska, E Noel, M Rashid, ... Nature communications 9 (1), 1044, 2018 | 48 | 2018 |
| Attenuation of disease phenotype through alternative translation initiation in low‐penetrance retinoblastoma F Sánchez‐Sánchez, C Ramírez‐Castillejo, DB Weekes, M Beneyto, ... Human mutation 28 (2), 159-167, 2007 | 46 | 2007 |
| Functional screening reveals HORMAD1-driven gene dependencies associated with translesion synthesis and replication stress tolerance D Tarantino, C Walker, D Weekes, H Pemberton, K Davidson, G Torga, ... Oncogene 41 (32), 3969-3977, 2022 | 11 | 2022 |
| Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency I Bajrami, C Walker, DB Krastev, D Weekes, F Song, AJ Wicks, ... Communications biology 4 (1), 1270, 2021 | 5 | 2021 |
| New regulators of the BRCA1 response to genotoxic stress JR Morris, C Boutell, M Keppler, R Densham, D Weekes, A Alamshah, ... Breast Cancer Research 12, 1-1, 2010 | 2 | 2010 |
| P36. The role of FGF-signalling in osteosarcoma: A potential therapeutic target? D Weekes, T Kashima, A Grigoriadis Cancer Treatment Reviews 34, 26, 2008 | 2 | 2008 |
| Hormad1 therapeutics A Tutt, C Walker, D Weekes, J Pines, C Lord US Patent App. 18/266,190, 2024 | | 2024 |
| HORMAD1 drives spindle assembly checkpoint defects and sensitivity to multiple mitotic kinases C Walker, D Weekes, G Torga, J Quist, J Trendell, L Hitchens, A Martin, ... European Journal of Cancer 174, S66, 2022 | | 2022 |
| The anion channel GPR89 is a novel oncogene associated with tumour specific dependency in breast cancer R Ferro, A Carroll, A Mendes-Pereira, V Reen, I Roxanis, S Annunziato, ... European Journal of Cancer 174, S50, 2022 | | 2022 |
| Mechanisms Involved in Ceramide-Induced Autophagy in Osteoblasts NA Al-Hazmi, TY Alhazzazi, SMN Bukhary, D Weekes, F McDonald, P Hill, ... Archives of Pharmacy Practice 12 (3-2021), 125-133, 2021 | | 2021 |
| The anion channel GPHR/GPR89 regulates protein-folding homeostasis by regulating the IRE1α pathway in breast cancer R Ferro, P Marra, AM Pereira, V Reen, C Prince, S Mathew, A Facchetti, ... Cancer Research 78 (13_Supplement), 443-443, 2018 | | 2018 |
| A high-throughput functional screen reveals synthetic lethal interactions associated with replication stress in HORMAD1-expressing triple-negative breast cancers D Tarantino, C Walker, D Weekes, H Pemberton, J Frankum, R Brough, ... Cancer Research 78 (13_Supplement), 344-344, 2018 | | 2018 |
