AJ Sedgewick
AJ Sedgewick
Senior Research Scientist, Machine Learning, NantHealth
Verified email at nanthealth.com
Title
Cited by
Cited by
Year
Transcriptional programming of normal and inflamed human epidermis at single-cell resolution
JB Cheng, AJ Sedgewick, AI Finnegan, P Harirchian, J Lee, S Kwon, ...
Cell reports 25 (4), 871-883, 2018
812018
Learning mixed graphical models with separate sparsity parameters and stability-based model selection
AJ Sedgewick, I Shi, RM Donovan, PV Benos
BMC bioinformatics 17 (5), 307-318, 2016
412016
Efficient stochastic simulation of chemical kinetics networks using a weighted ensemble of trajectories
RM Donovan, AJ Sedgewick, JR Faeder, DM Zuckerman
The Journal of chemical physics 139 (11), 09B642_1, 2013
412013
Learning subgroup-specific regulatory interactions and regulator independence with PARADIGM
AJ Sedgewick, SC Benz, S Rabizadeh, P Soon-Shiong, CJ Vaske
Bioinformatics 29 (13), i62-i70, 2013
362013
Mixed graphical models for integrative causal analysis with application to chronic lung disease diagnosis and prognosis
AJ Sedgewick, K Buschur, I Shi, JD Ramsey, VK Raghu, DV Manatakis, ...
Bioinformatics 35 (7), 1204-1212, 2019
302019
PARP1 rs1805407 increases sensitivity to PARP1 inhibitors in cancer cells suggesting an improved therapeutic strategy
I Abecassis, AJ Sedgewick, M Romkes, S Buch, T Nukui, MG Kapetanaki, ...
Scientific reports 9 (1), 1-9, 2019
132019
Data-independent acquisition mass spectrometry to quantify protein levels in FFPE tumor biopsies for molecular diagnostics
YJ Kim, SMM Sweet, JD Egertson, AJ Sedgewick, S Woo, W Liao, ...
Journal of proteome research 18 (1), 426-435, 2018
122018
Mixed graphical models for causal analysis of multi-modal variables
AJ Sedgewick, JD Ramsey, P Spirtes, C Glymour, PV Benos
arXiv preprint arXiv:1704.02621, 2017
82017
A20 and ABIN1 suppression of a keratinocyte inflammatory program with a shared single-cell expression signature in diverse human rashes
P Harirchian, J Lee, S Hilz, AJ Sedgewick, BEP White, MJ Kesling, T Mully, ...
Journal of Investigative Dermatology 139 (6), 1264-1273, 2019
42019
Investigating tumoral and temporal heterogeneity through comprehensive-omics profiling in patients with metastatic triple negative breast cancer.
C Szeto, R Parulkar, AJ Sedgewick, SC Benz, F Cecchi, TA Hembrough, ...
Journal of Clinical Oncology 35 (15_suppl), 1093-1093, 2017
42017
Regional molecular signature of the symptomatic atherosclerotic carotid plaque
EM Caparosa, AJ Sedgewick, G Zenonos, Y Zhao, DL Carlisle, ...
Neurosurgery 85 (2), E284-E293, 2019
32019
Graphical models for de novo and pathway-based network prediction over multi-modal high-throughput biological data
A Sedgewick
University of Pittsburgh, 2016
32016
Single-cell profiling reveals divergent, globally patterned immune responses in murine skin inflammation
Y Liu, C Cook, AJ Sedgewick, S Zhang, MS Fassett, ...
Iscience 23 (10), 101582, 2020
22020
Large scale, robust, and accurate whole transcriptome profiling from clinical formalin-fixed paraffin-embedded samples
Y Newton, AJ Sedgewick, L Cisneros, J Golovato, M Johnson, CW Szeto, ...
Scientific reports 10 (1), 1-11, 2020
22020
Comprehensive proteomic and genomic profiling to identify therapeutic targets in adenoid cystic carcinoma.
SP Thyparambil, YJ Kim, A Chambers, D Yan, S Sellappan, C Gong, ...
Journal of Clinical Oncology 36 (15_suppl), 6053-6053, 2018
12018
T-cell receptor clonotyping and immune infiltrate quantification with whole transcriptome RNA-seq from FFPE
AJ Sedgewick, JJ Adashek, CW Szeto, CJ Vaske, PE Spiess, SC Benz
Cancer Research 80 (16 Supplement), 4980-4980, 2020
2020
Investigating tumoral and temporal heterogeneity through comprehensive-omics profiling in patients with metastatic triple negative breast cancer
C Szeto, R Parulkar, A Sedgewick
US Patent App. 16/617,844, 2020
2020
MODELING miRNA INDUCED SILENCING IN BREAST CANCER WITH PARADIGM
A Sedgewick, S Rabizadeh, P Soon-Shiong, CJ Vaske
US Patent App. 16/498,857, 2020
2020
PARP1 rs1805407 Increases Sensitivity to PARP1 Inhibitors in Cancer Cells Suggesting an Improved Therapeutic Strategy
A Irina, AJ Sedgewick, R Marjorie, B Shama, N Tomoko, MG Kapetanaki, ...
Scientific Reports (Nature Publisher Group) 9 (1), 2019
2019
Mds to aml transition and prediction methods therefor
SC Benz, A Nguyen, AJ Sedgewick, C Szeto
US Patent App. 16/345,686, 2019
2019
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