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Richard J. Wall
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Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition
S Wyllie, S Brand, M Thomas, M De Rycker, C Chung, I Pena, ...
Proceedings of the National Academy of Sciences 116 (19), 9318-9323, 2019
1382019
Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation
DS Guttery, B Poulin, A Ramaprasad, RJ Wall, DJP Ferguson, D Brady, ...
Cell host & microbe 16 (1), 128-140, 2014
1312014
Clinical and veterinary trypanocidal benzoxaboroles target CPSF3
RJ Wall, E Rico, I Lukac, F Zuccotto, S Elg, IH Gilbert, Y Freund, ...
Proceedings of the National Academy of Sciences 115 (38), 9616-9621, 2018
1152018
Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite
B Poulin, EM Patzewitz, D Brady, O Silvie, MH Wright, DJP Ferguson, ...
Biology open 2 (11), 1160-1170, 2013
682013
Plasmodium P-type cyclin CYC3 modulates endomitotic growth during oocyst development in mosquitoes
M Roques, RJ Wall*, AP Douglass, A Ramaprasad, DJP Ferguson, ...
PLoS pathogens 11 (11), e1005273 *Joint first author, 2015
672015
Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani
V Corpas-Lopez, S Moniz, M Thomas, RJ Wall, LS Torrie, D Zander-Dinse, ...
ACS infectious diseases 5 (1), 111-122, 2018
652018
The Repeat Region of the Circumsporozoite Protein is Critical for Sporozoite Formation and Maturation in Plasmodium
DJP Ferguson, AE Balaban, EM Patzewitz, RJ Wall, CS Hopp, B Poulin, ...
PloS one 9 (12), e113923, 2014
582014
An ancient protein phosphatase, SHLP1, is critical to microneme development in Plasmodium ookinetes and parasite transmission
EM Patzewitz, DS Guttery, B Poulin, C Ramakrishnan, DJP Ferguson, ...
Cell reports 3 (3), 622-629, 2013
572013
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis
CE Mowbray, S Braillard, PA Glossop, GA Whitlock, RT Jacobs, J Speake, ...
Journal of Medicinal Chemistry 64 (21), 16159–16176, 2021
452021
Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility
JL Green, RJ Wall, J Vahokoski, NA Yusuf, MAM Ridzuan, RR Stanway, ...
Journal of Biological Chemistry 292 (43), 17857-17875, 2017
432017
SAS6-like protein in Plasmodium indicates that conoid-associated apical complex proteins persist in invasive stages within the mosquito vector
RJ Wall, M Roques, NJ Katris, L Koreny, RR Stanway, D Brady, RF Waller, ...
Scientific reports 6 (1), 28604, 2016
412016
Characterisation of chlorinated, brominated and mixed halogenated dioxins, furans and biphenyls as potent and as partial agonists of the Aryl hydrocarbon receptor
RJ Wall, A Fernandes, M Rose, DR Bell, IR Mellor
Environment international 76, 49-56, 2015
402015
Systematic analysis of Plasmodium myosins reveals differential expression, localization and function in invasive and proliferative parasite stages
RJ Wall, M Zeeshan, NJ Katris, R Limenitakis, E Rea, J Stock, D Brady, ...
Cellular microbiology 21 (10), e13082, 2019
382019
The Plasmodium class XIV myosin, MyoB, has a distinct subcellular location in invasive and motile stages of the malaria parasite and an unusual light chain
NA Yusuf, JL Green, RJ Wall, E Knuepfer, RW Moon, C Schulte-Huxel, ...
Journal of Biological Chemistry 290 (19), 12147-12164, 2015
382015
Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis
RJ Wall, DJP Ferguson, A Freville, B Franke-Fayard, D Brady, M Zeeshan, ...
Scientific Reports 8 (1), 5610, 2018
372018
Plasmodium condensin core subunits (SMC2/SMC4) mediate atypical mitosis and are essential for parasite proliferation and transmission
R Pandey, S Abel, M Boucher, RJ Wall, M Zeeshan, E Rea, A Freville, ...
Cell reports 30, 1-15, 2020
272020
The role of folate transport in antifolate drug action in Trypanosoma brucei
S Dewar, N Sienkiewicz, HB Ong, RJ Wall, D Horn, AH Fairlamb
Journal of Biological Chemistry 291 (47), 24768-24778, 2016
272016
The Qi site of cytochrome b is a promiscuous drug target in Trypanosoma cruzi and Leishmania donovani
RJ Wall, S Carvalho, R Milne, JA Bueren-Calabuig, S Moniz, ...
ACS infectious diseases 6 (3), 515-528, 2020
252020
Mixed halogenated dioxins/furans (PXDD/Fs) and biphenyls (PXBs) in food: occurrence and toxic equivalent exposure using specific relative potencies
AR Fernandes, D Mortimer, RJ Wall, DR Bell, M Rose, M Carr, S Panton, ...
Environment international 73, 104-110, 2014
252014
Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context
RJ Wall, G He, MS Denison, C Congiu, V Onnis, A Fernandes, DR Bell, ...
Toxicology 297 (1-3), 26-33, 2012
212012
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Articles 1–20