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Richard J. Wall
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Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition
S Wyllie, S Brand, M Thomas, M De Rycker, C Chung, I Pena, ...
Proceedings of the National Academy of Sciences 116 (19), 9318-9323, 2019
1252019
Genome-wide functional analysis of Plasmodium protein phosphatases reveals key regulators of parasite development and differentiation
DS Guttery, B Poulin, A Ramaprasad, RJ Wall, DJP Ferguson, D Brady, ...
Cell host & microbe 16 (1), 128-140, 2014
1212014
Clinical and veterinary trypanocidal benzoxaboroles target CPSF3
RJ Wall, E Rico, I Lukac, F Zuccotto, S Elg, IH Gilbert, Y Freund, ...
Proceedings of the National Academy of Sciences 115 (38), 9616-9621, 2018
1062018
Plasmodium P-type cyclin CYC3 modulates endomitotic growth during oocyst development in mosquitoes
M Roques, RJ Wall*, AP Douglass, A Ramaprasad, DJP Ferguson, ...
PLoS pathogens 11 (11), e1005273 *Joint first author, 2015
632015
Unique apicomplexan IMC sub-compartment proteins are early markers for apical polarity in the malaria parasite
B Poulin, EM Patzewitz, D Brady, O Silvie, MH Wright, DJP Ferguson, ...
Biology open 2 (11), 1160-1170, 2013
632013
Pharmacological Validation of N-Myristoyltransferase as a Drug Target in Leishmania donovani
V Corpas-Lopez, S Moniz, M Thomas, RJ Wall, LS Torrie, D Zander-Dinse, ...
ACS infectious diseases 5 (1), 111-122, 2018
622018
The Repeat Region of the Circumsporozoite Protein is Critical for Sporozoite Formation and Maturation in Plasmodium
DJP Ferguson, AE Balaban, EM Patzewitz, RJ Wall, CS Hopp, B Poulin, ...
PloS one 9 (12), e113923, 2014
542014
An ancient protein phosphatase, SHLP1, is critical to microneme development in Plasmodium ookinetes and parasite transmission
EM Patzewitz, DS Guttery, B Poulin, C Ramakrishnan, DJP Ferguson, ...
Cell reports 3 (3), 622-629, 2013
542013
Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility
JL Green, RJ Wall, J Vahokoski, NA Yusuf, MAM Ridzuan, RR Stanway, ...
Journal of Biological Chemistry 292 (43), 17857-17875, 2017
412017
SAS6-like protein in Plasmodium indicates that conoid-associated apical complex proteins persist in invasive stages within the mosquito vector
RJ Wall, M Roques, NJ Katris, L Koreny, RR Stanway, D Brady, RF Waller, ...
Scientific reports 6 (1), 28604, 2016
412016
Characterisation of chlorinated, brominated and mixed halogenated dioxins, furans and biphenyls as potent and as partial agonists of the Aryl hydrocarbon receptor
RJ Wall, A Fernandes, M Rose, DR Bell, IR Mellor
Environment international 76, 49-56, 2015
402015
The Plasmodium class XIV myosin, MyoB, has a distinct subcellular location in invasive and motile stages of the malaria parasite and an unusual light chain
NA Yusuf, JL Green, RJ Wall, E Knuepfer, RW Moon, C Schulte-Huxel, ...
Journal of Biological Chemistry 290 (19), 12147-12164, 2015
392015
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis
CE Mowbray, S Braillard, PA Glossop, GA Whitlock, RT Jacobs, J Speake, ...
Journal of Medicinal Chemistry 64 (21), 16159–16176, 2021
352021
Systematic analysis of Plasmodium myosins reveals differential expression, localization and function in invasive and proliferative parasite stages
RJ Wall, M Zeeshan, NJ Katris, R Limenitakis, E Rea, J Stock, D Brady, ...
Cellular microbiology 21 (10), e13082, 2019
342019
Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis
RJ Wall, DJP Ferguson, A Freville, B Franke-Fayard, D Brady, M Zeeshan, ...
Scientific Reports 8 (1), 5610, 2018
312018
The role of folate transport in antifolate drug action in Trypanosoma brucei
S Dewar, N Sienkiewicz, HB Ong, RJ Wall, D Horn, AH Fairlamb
Journal of Biological Chemistry 291 (47), 24768-24778, 2016
272016
Plasmodium condensin core subunits (SMC2/SMC4) mediate atypical mitosis and are essential for parasite proliferation and transmission
R Pandey, S Abel, M Boucher, RJ Wall, M Zeeshan, E Rea, A Freville, ...
Cell reports 30, 1-15, 2020
252020
The Qi site of cytochrome b is a promiscuous drug target in Trypanosoma cruzi and Leishmania donovani
RJ Wall, S Carvalho, R Milne, JA Bueren-Calabuig, S Moniz, ...
ACS infectious diseases 6 (3), 515-528, 2020
252020
Mixed halogenated dioxins/furans (PXDD/Fs) and biphenyls (PXBs) in food: Occurrence and toxic equivalent exposure using specific relative potencies
AR Fernandes, D Mortimer, RJ Wall, DR Bell, M Rose, M Carr, S Panton, ...
Environment international 73, 104-110, 2014
232014
Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context
RJ Wall, G He, MS Denison, C Congiu, V Onnis, A Fernandes, DR Bell, ...
Toxicology 297 (1-3), 26-33, 2012
202012
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