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Dan Patton
Dan Patton
Zymeworks
Verified email at mail.ubc.ca
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Year
Cutting edge: the phosphoinositide 3-kinase p110δ is critical for the function of CD4+ CD25+ Foxp3+ regulatory T cells
DT Patton, OA Garden, WP Pearce, LE Clough, CR Monk, E Leung, ...
The Journal of Immunology 177 (10), 6598-6602, 2006
3442006
The p110δ isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells
K Okkenhaug, DT Patton, A Bilancio, F Garšon, WC Rowan, ...
The Journal of Immunology 177 (8), 5122-5128, 2006
2272006
PI3K p110δ regulates T-cell cytokine production during primary and secondary immune responses in mice and humans
DR Soond, E Bj°rgo, K Moltu, VQ Dale, DT Patton, KM Torgersen, ...
Blood, The Journal of the American Society of Hematology 115 (11), 2203-2213, 2010
2102010
CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer
F Garšon, DT Patton, JL Emery, E Hirsch, R Rottapel, T Sasaki, ...
Blood, The Journal of the American Society of Hematology 111 (3), 1464-1471, 2008
1602008
The PI3K p110δ regulates expression of CD38 on regulatory T cells
DT Patton, MD Wilson, WC Rowan, DR Soond, K Okkenhaug
PloS one 6 (3), e17359, 2011
982011
P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine–dependent neutrophil responses
CD Lawson, S Donald, KE Anderson, DT Patton, HCE Welch
The Journal of Immunology 186 (3), 1467-1476, 2011
702011
Ig gene-like molecule CD31 plays a nonredundant role in the regulation of T-cell immunity and tolerance
L Ma, C Mauro, GH Cornish, JG Chai, D Coe, H Fu, D Patton, ...
Proceedings of the National Academy of Sciences 107 (45), 19461-19466, 2010
642010
Does the PI3K pathway promote or antagonize regulatory T cell development and function?
DR Soond, ECM Slack, OA Garden, DT Patton, K Okkenhaug
Frontiers in immunology 3, 244, 2012
442012
The PI3K p110δ controls T-cell development, differentiation and regulation
DT Patton, F Garcon, K Okkenhaug
Biochemical Society Transactions 35 (2), 167-171, 2007
392007
Pten loss in CD4 T cells enhances their helper function but does not lead to autoimmunity or lymphoma
DR Soond, F Garšon, DT Patton, J Rolf, M Turner, C Scudamore, ...
The Journal of Immunology 188 (12), 5935-5943, 2012
382012
Interleukin-7, but not thymic stromal lymphopoietin, plays a key role in the T cell response to influenza A virus
AW Plumb, DT Patton, JH Seo, EK Loveday, F Jean, SF Ziegler, ...
PloS one 7 (11), e50199, 2012
342012
The survival and differentiation of pro-B and pre-B cells in the bone marrow is dependent on IL-7Rα Tyr449
DT Patton, AW Plumb, N Abraham
The Journal of Immunology 193 (7), 3446-3455, 2014
252014
Elevated IL-7 availability does not account for T cell proliferation in moderate lymphopenia
LC Osborne, DT Patton, JH Seo, N Abraham
The Journal of Immunology 186 (4), 1981-1988, 2011
152011
Identification of an HLA‐A* 0201 cytotoxic T lymphocyte epitope specific to the endothelial antigen Tie‐2
JM Ramage, R Metheringham, A Conn, I Spendlove, RS Moss, DT Patton, ...
International journal of cancer 110 (2), 245-250, 2004
152004
Interleukin‐7 in the transition of bone marrow progenitors to the thymus
AW Plumb, A Sheikh, DA Carlow, DT Patton, HJ Ziltener, N Abraham
Immunology and Cell Biology 95 (10), 916-924, 2017
142017
Loss of phosphatidylinositol 3-kinase activity in regulatory T cells leads to neuronal inflammation
AK Stark, ECM Davenport, DT Patton, CL Scudamore, B Vanhaesebroeck, ...
The Journal of Immunology 205 (1), 78-89, 2020
132020
The development and survival but not function of follicular B cells is dependent on IL-7Rα Tyr449 signaling
DT Patton, AW Plumb, SA Redpath, LC Osborne, G Perona-Wright, ...
Plos one 9 (2), e88771, 2014
92014
PI3K p110 delta controls the differentiation and function of regulatory T cells
DT Patton, JL Emery, WC Rowan, K Okkenhaug
Immunology 125, 129-129, 2008
22008
Glucocorticoid Synthesis By Mouse Bone Marrow and Spleen
MD Taves, AW Plumb, DT Patton, C Ma, N Abraham, KK Soma
ENDOCRINE REVIEWS 35 (3), 2014
12014
Understanding the geometry and valency of bispecific antibodies in the optimization of tumor-dependent activation of 4-1BB
A Von Rossum, H Pratap, L Newhook, EC Halvorsen, L Freiburger, ...
Cancer Research 81 (13_Supplement), 1737-1737, 2021
2021
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