|HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT|
F Bruzzese, A Leone, M Rocco, C Carbone, G Piro, M Caraglia, ...
Journal of cellular physiology 226 (9), 2378-2390, 2011
|New perspective for an old antidiabetic drug: metformin as anticancer agent|
A Leone, E Di Gennaro, F Bruzzese, A Avallone, A Budillon
Advances in Nutrition and Cancer, 355-376, 2014
|Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or raltitrexed|
E Di Gennaro, F Bruzzese, S Pepe, A Leone, P Delrio, P Subbarayan, ...
Cancer biology & therapy 8 (9), 782-791, 2009
|Local and systemic protumorigenic effects of cancer-associated fibroblast-derived GDF15|
F Bruzzese, C Hägglöf, A Leone, E Sjöberg, MS Roca, S Kiflemariam, ...
Cancer research 74 (13), 3408-3417, 2014
|Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells|
MR Milone, B Pucci, F Bruzzese, C Carbone, G Piro, S Costantini, ...
Cell death & disease 4 (5), e641, 2013
|Endothelial progenitor cells, defined by the simultaneous surface expression of VEGFR 2 and CD 133, are not detectable in healthy peripheral and cord blood|
P Lanuti, G Rotta, C Almici, G Avvisati, A Budillon, P Doretto, N Malara, ...
Cytometry Part A 89 (3), 259-270, 2016
|Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway|
A Leone, MS Roca, C Ciardiello, M Terranova-Barberio, C Vitagliano, ...
Free Radical Biology and Medicine 89, 287-299, 2015
|Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways|
F Bruzzese, B Pucci, MR Milone, C Ciardiello, R Franco, MI Chianese, ...
Cell death & disease 4 (10), e878, 2013
|Oxidative stress gene expression profile correlates with cancer patient poor prognosis: identification of crucial pathways might select novel therapeutic approaches|
A Leone, MS Roca, C Ciardiello, S Costantini, A Budillon
Oxidative medicine and cellular longevity 2017, 2017
|Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression|
M Terranova-Barberio, MS Roca, AI Zotti, A Leone, F Bruzzese, ...
Oncotarget 7 (7), 7715, 2016
|Enhancement of 5-FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles|
A Russo, S Maiolino, V Pagliara, F Ungaro, F Tatangelo, A Leone, ...
Oncotarget 7 (48), 79670, 2016
|Critical role of bevacizumab scheduling in combination with pre-surgical chemo-radiotherapy in MRI-defined high-risk locally advanced rectal cancer: Results of the BRANCH trial|
A Avallone, B Pecori, F Bianco, L Aloj, F Tatangelo, C Romano, V Granata, ...
Oncotarget 6 (30), 30394, 2015
|Figli per sempre|
A Battaglia, A Canevaro, M Chiurchiu, A Leone, MM Pierro, AM Sorrentino
La cura continua del disabile mentale, Carocci Faber, Roma, 2002
|Management of non-small cell lung cancer in the era of personalized medicine|
G Rocco, A Morabito, A Leone, P Muto, F Fiore, A Budillon
The international journal of biochemistry & cell biology 78, 173-179, 2016
|Proteomic analysis identifies differentially expressed proteins after HDAC vorinostat and EGFR inhibitor gefitinib treatments in Hep‐2 cancer cells|
L Bianchi, F Bruzzese, A Leone, A Gagliardi, M Puglia, E Di Gennaro, ...
Proteomics 11 (18), 3725-3742, 2011
|Multidisciplinary approach to rectal cancer: are we ready for selective treatment strategies?|
A Avallone, L Aloj, P Delrio, B Pecori, A Leone, F Tatangelo, F Perri, ...
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2013
|mTORC1-driven tumor cells are highly sensitive to therapeutic targeting by antagonists of oxidative stress|
J Li, S Shin, Y Sun, SO Yoon, C Li, E Zhang, J Yu, J Zhang, J Blenis
Cancer research 76 (16), 4816-4827, 2016
|A randomized phase 3 study on the optimization of the combination of bevacizumab with FOLFOX/OXXEL in the treatment of patients with metastatic colorectal cancer-OBELICS …|
A Avallone, MC Piccirillo, L Aloj, G Nasti, P Delrio, F Izzo, E Di Gennaro, ...
BMC cancer 16 (1), 69, 2016
|Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression|
C Ciardiello, MS Roca, A Noto, F Bruzzese, T Moccia, C Vitagliano, ...
Oncotarget 7 (15), 19559, 2016
|Synergistic antitumor interaction between valproic acid, capecitabine and radiotherapy in colorectal cancer: critical role of p53|
M Terranova-Barberio, B Pecori, MS Roca, S Imbimbo, F Bruzzese, ...
Journal of Experimental & Clinical Cancer Research 36 (1), 177, 2017