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John T. Cunningham
John T. Cunningham
Department of Cancer Biology, University of Cincinnati College of Medicine
Verified email at ucmail.uc.edu
Title
Cited by
Cited by
Year
mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex
JT Cunningham, JT Rodgers, DH Arlow, F Vazquez, VK Mootha, ...
nature 450 (7170), 736-740, 2007
16462007
ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth
LS Hart, JT Cunningham, T Datta, S Dey, F Tameire, SL Lehman, BO Qiu, ...
The Journal of clinical investigation 122 (12), 4621-4634, 2012
4262012
Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer
JT Cunningham, MV Moreno, A Lodi, SM Ronen, D Ruggero
Cell 157 (5), 1088-1103, 2014
2342014
Translation control of the immune checkpoint in cancer and its therapeutic targeting
Y Xu, M Poggio, HY Jin, Z Shi, CM Forester, Y Wang, CR Stumpf, L Xue, ...
Nature medicine 25 (2), 301-311, 2019
2102019
Development of a stress response therapy targeting aggressive prostate cancer
HG Nguyen, CS Conn, Y Kye, L Xue, CM Forester, JE Cowan, AC Hsieh, ...
Science translational medicine 10 (439), eaar2036, 2018
1462018
Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling
SM Blättler, JT Cunningham, F Verdeguer, H Chim, W Haas, H Liu, ...
Cell metabolism 15 (4), 505-517, 2012
1052012
Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle
SM Blättler, F Verdeguer, M Liesa, JT Cunningham, RO Vogel, H Chim, ...
Molecular and cellular biology 32 (16), 3333-3346, 2012
922012
Noninvasive Measurement of mTORC1 Signaling with 89Zr-Transferrin
C Truillet, JT Cunningham, MFL Parker, LT Huynh, CS Conn, D Ruggero, ...
Clinical Cancer Research 23 (12), 3045-3052, 2017
262017
POPULATION GENETICS OF RESURGENCE: WHITE-TAILED DEER IN KENTUCKY
KC Doerner, W Braden, J Cork, T Cunningham, A Rice, BJ Furman, ...
Journal of Wildlife Management 69 (1), 345-355, 2005
262005
Tobacco smoking induces metabolic reprogramming of renal cell carcinoma
J Reigle, D Secic, J Biesiada, C Wetzel, B Shamsaei, J Chu, Y Zang, ...
The Journal of clinical investigation 131 (1), 2021
182021
New connections between old pathways: PDK1 signaling promotes cellular transformation through PLK1-dependent MYC stabilization
JT Cunningham, D Ruggero
Cancer discovery 3 (10), 1099-1102, 2013
182013
Molecular and metabolic subtypes in sporadic and inherited clear cell renal cell carcinoma
MF Czyzyk-Krzeska, JA Landero Figueroa, S Gulati, JT Cunningham, ...
Genes 12 (3), 388, 2021
122021
Decreased genetic dosage of hepatic Yin Yang 1 causes diabetic-like symptoms
F Verdeguer, SM Blättler, JT Cunningham, JA Hall, H Chim, P Puigserver
Molecular Endocrinology 28 (3), 308-316, 2014
122014
Investigating Myc-dependent translational regulation in normal and cancer cells
JT Cunningham, M Pourdehnad, CR Stumpf, D Ruggero
The Myc Gene: Methods and Protocols, 201-212, 2013
102013
Complimentary transcriptomic-metallomic analysis identifies risk of relapse for clear-cell renal cell carcinoma (ccRCC) patients.
S Gulati, B Vemuri, D Secic, B Shamsaei, DR Plas, JT Cunningham, ...
Journal of Clinical Oncology 40 (6_suppl), 378-378, 2022
2022
Metabolic subtypes of clear cell renal cell carcinoma defined by tobacco smoking
MF Czyzyk-Krzeska, J Meller, JA Landero Figueroa, DR Plas, ...
Molecular & Cellular Oncology 8 (2), 1859917, 2021
2021
Molecular and Metabolic Subtypes in Sporadic and Inherited Clear Cell Renal Cell Carcinoma. Genes 2021, 12, 388
MF Czyzyk-Krzeska, JA Landero Figueroa, S Gulati, JT Cunningham, ...
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021
2021
Phosphoribosyl pyrophosphate synthetase 2 (PRPS2) as a therapeutic target in cancer treatment
D Ruggero, JT Cunningham
US Patent 9,765,337, 2017
2017
Abstract A25: Sensing stress in cancer: a novel therapy targeting protein synthesis through the unfolded protein response in prostate cancer development
CS Conn, HG Nguyen, Y Kye, JT Cunningham, C Truillet, M Evans, ...
Cancer Research 77 (6_Supplement), A25-A25, 2017
2017
Sensing stress in cancer: a novel therapy targeting protein synthesis through the unfolded protein response in prostate cancer development
CS Conn, HG Nguyen, Y Kye, JT Cunningham, C Truillet, M Evans, ...
CANCER RESEARCH 77, 2017
2017
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