Rebecca A Burrell
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The causes and consequences of genetic heterogeneity in cancer evolution
RA Burrell, N McGranahan, J Bartek, C Swanton
Nature 501 (7467), 338-345, 2013
Replication stress links structural and numerical cancer chromosomal instability
RA Burrell, SE McClelland, D Endesfelder, P Groth, MC Weller, N Shaikh, ...
Nature 494 (7438), 492-496, 2013
Tumour heterogeneity and the evolution of polyclonal drug resistance
RA Burrell, C Swanton
Molecular oncology 8 (6), 1095-1111, 2014
Cancer chromosomal instability: therapeutic and diagnostic challenges: ‘Exploring aneuploidy: the significance of chromosomal imbalance’review series
N McGranahan, RA Burrell, D Endesfelder, MR Novelli, C Swanton
EMBO reports 13 (6), 528-538, 2012
Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution
SM Dewhurst, N McGranahan, RA Burrell, AJ Rowan, E Grönroos, ...
Cancer discovery 4 (2), 175-185, 2014
Cancer: evolution within a lifetime
M Gerlinger, N McGranahan, SM Dewhurst, RA Burrell, I Tomlinson, ...
Annual review of genetics 48 (1), 215-236, 2014
Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer
R Roylance, D Endesfelder, P Gorman, RA Burrell, J Sander, I Tomlinson, ...
Cancer epidemiology, biomarkers & prevention 20 (10), 2183-2194, 2011
SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair
N Kanu, E Grönroos, P Martinez, RA Burrell, X Yi Goh, J Bartkova, ...
Oncogene 34 (46), 5699-5708, 2015
Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast …
N Juul, Z Szallasi, AC Eklund, Q Li, RA Burrell, M Gerlinger, V Valero, ...
The lancet oncology 11 (4), 358-365, 2010
Genome‐wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target
M Gerlinger, CR Santos, B Spencer‐Dene, P Martinez, D Endesfelder, ...
The Journal of pathology 227 (2), 146-156, 2012
Chromosomal instability: a composite phenotype that influences sensitivity to chemotherapy
SE McClelland, RA Burrell, C Swanton
Cell cycle 8 (20), 3262-3266, 2009
BCL9L dysfunction impairs caspase-2 expression permitting aneuploidy tolerance in colorectal cancer
C López-García, L Sansregret, E Domingo, N McGranahan, S Hobor, ...
Cancer cell 31 (1), 79-93, 2017
Parallel evolution of tumour subclones mimics diversity between tumours
P Martinez, NJ Birkbak, M Gerlinger, N McGranahan, RA Burrell, ...
The Journal of pathology 230 (4), 356-364, 2013
Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER+ Breast Cancer
D Endesfelder, RA Burrell, N Kanu, N McGranahan, M Howell, PJ Parker, ...
Cancer research 74 (17), 4853-4863, 2014
The evolution of the unstable cancer genome
RA Burrell, C Swanton
Current opinion in genetics & development 24, 61-67, 2014
Breast cancer genome heterogeneity: a challenge to personalised medicine?
C Swanton, RA Burrell, PA Futreal
Breast Cancer Research 13, 1-2, 2011
RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress
N Kanu, T Zhang, RA Burrell, A Chakraborty, J Cronshaw, C DaCosta, ...
Oncogene 35 (30), 4009-4019, 2016
Targeting chromosomal instability and tumour heterogeneity in HER2‐positive breast cancer
RA Burrell, N Juul, SR Johnston, JS Reis‐Filho, Z Szallasi, C Swanton
Journal of cellular biochemistry 111 (4), 782-790, 2010
Re-evaluating clonal dominance in cancer evolution
RA Burrell, C Swanton
Trends in Cancer 2 (5), 263-276, 2016
Expression of regulators of mitotic fidelity are associated with intercellular heterogeneity and chromosomal instability in primary breast cancer
R Roylance, D Endesfelder, M Jamal-Hanjani, RA Burrell, P Gorman, ...
Breast cancer research and treatment 148, 221-229, 2014
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