| Plastic adherent stromal cells from the bone marrow of commonly used strains of inbred mice: variations in yield, growth, and differentiation DG Phinney, G Kopen, RL Isaacson, DJ Prockop Journal of cellular biochemistry 72 (4), 570-585, 1999 | 859 | 1999 |
| Insights into adaptor binding to the AAA protein p97 HO Yeung, P Kloppsteck, H Niwa, RL Isaacson, S Matthews, X Zhang, ... Biochemical Society Transactions 36 (1), 62-67, 2008 | 175 | 2008 |
| A new labeling method for methyl transverse relaxation-optimized spectroscopy NMR spectra of alanine residues RL Isaacson, PJ Simpson, M Liu, E Cota, X Zhang, P Freemont, ... Journal of the American Chemical Society 129 (50), 15428-15429, 2007 | 140 | 2007 |
| Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites S Park, R Isaacson, HT Kim, PA Silver, G Wagner Structure 13 (7), 995-1005, 2005 | 136 | 2005 |
| Conformational changes in the AAA ATPase p97–p47 adaptor complex F Beuron, I Dreveny, X Yuan, VE Pye, C Mckeown, LC Briggs, MJ Cliff, ... The EMBO journal 25 (9), 1967-1976, 2006 | 127 | 2006 |
| p97 and close encounters of every kind: a brief review I Dreveny, VE Pye, F Beuron, LC Briggs, RL Isaacson, SJ Matthews, ... Biochemical Society Transactions 32 (5), 715-720, 2004 | 98 | 2004 |
| Loss of a metal-binding site in gelsolin leads to familial amyloidosis–Finnish type SL Kazmirski, RL Isaacson, C An, A Buckle, CM Johnson, V Daggett, ... nature structural biology 9 (2), 112-116, 2002 | 93 | 2002 |
| Detailed structural insights into the p97-Npl4-Ufd1 interface RL Isaacson, VE Pye, P Simpson, HH Meyer, X Zhang, PS Freemont, ... Journal of Biological Chemistry 282 (29), 21361-21369, 2007 | 83 | 2007 |
| Intrinsically disordered proteins: modes of binding with emphasis on disordered domains OM Morris, JH Torpey, RL Isaacson Open biology 11 (10), 210222, 2021 | 69 | 2021 |
| Structural insights into serine-rich fimbriae from Gram-positive bacteria S Ramboarina, JA Garnett, M Zhou, Y Li, Z Peng, JD Taylor, W Lee, ... Journal of Biological Chemistry 285 (42), 32446-32457, 2010 | 69 | 2010 |
| Equilibria and kinetics of folding of gelsolin domain 2 and mutants involved in familial amyloidosis–Finnish type RL Isaacson, AG Weeds, AR Fersht Proceedings of the National Academy of Sciences 96 (20), 11247-11252, 1999 | 66 | 1999 |
| The association of BAG6 with SGTA and tail-anchored proteins P Leznicki, QP Roebuck, L Wunderley, A Clancy, EM Krysztofinska, ... PloS one 8 (3), e59590, 2013 | 59 | 2013 |
| Autosomal-recessive hearing impairment due to rare missense variants within S1PR2 RLP Santos-Cortez, R Faridi, AU Rehman, K Lee, M Ansar, X Wang, ... The American Journal of Human Genetics 98 (2), 331-338, 2016 | 56 | 2016 |
| Structures of Get3, Get4, and Get5 provide new models for TA membrane protein targeting PJ Simpson, B Schwappach, HG Dohlman, RL Isaacson Structure 18 (8), 897-902, 2010 | 46 | 2010 |
| Automated assignment in selectively methyl-labeled proteins Y Xu, M Liu, PJ Simpson, R Isaacson, E Cota, J Marchant, D Yang, ... Journal of the American Chemical Society 131 (27), 9480-9481, 2009 | 44 | 2009 |
| Structure of the Sgt2/Get5 complex provides insights into GET-mediated targeting of tail-anchored membrane proteins AC Simon, PJ Simpson, RM Goldstone, EM Krysztofinska, JW Murray, ... Proceedings of the National Academy of Sciences 110 (4), 1327-1332, 2013 | 38 | 2013 |
| Structural and functional insights into the E3 ligase, RNF126 EM Krysztofinska, S Martínez-Lumbreras, A Thapaliya, NJ Evans, S High, ... Scientific reports 6 (1), 26433, 2016 | 37 | 2016 |
| S1PR2 variants associated with auditory function in humans and endocochlear potential decline in mouse NJ Ingham, F Carlisle, S Pearson, MA Lewis, A Buniello, J Chen, ... Scientific reports 6 (1), 28964, 2016 | 35 | 2016 |
| Elucidating the mechanism of familial amyloidosis–Finnish type: NMR studies of human gelsolin domain 2 SL Kazmirski, MJ Howard, RL Isaacson, AR Fersht Proceedings of the National Academy of Sciences 97 (20), 10706-10711, 2000 | 35 | 2000 |
| The roles of cytosolic quality control proteins, SGTA and the BAG6 complex, in disease R Benarroch, JM Austin, F Ahmed, RL Isaacson Advances in protein chemistry and structural biology 114, 265-313, 2019 | 31 | 2019 |
