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Ralf Kircheis
Ralf Kircheis
Director R&D Syntacoll / Innocoll
Verified email at syntacoll.de - Homepage
Title
Cited by
Cited by
Year
PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
M Ogris, S Brunner, S Schüller, R Kircheis, E Wagner
Gene therapy 6 (4), 595-605, 1999
15691999
Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo
L Wightman, R Kircheis, V Rössler, S Carotta, R Ruzicka, M Kursa, ...
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2001
9282001
Design and gene delivery activity of modified polyethylenimines
R Kircheis, L Wightman, E Wagner
Advanced drug delivery reviews 53 (3), 341-358, 2001
8942001
The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
M Ogris, P Steinlein, M Kursa, K Mechtler, R Kircheis, E Wagner
Gene therapy 5 (10), 1425-1433, 1998
7901998
Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery
R Kircheis, A Kichler, G Wallner, M Kursa, M Ogris, T Felzmann, ...
Gene therapy 4 (5), 409-418, 1997
5281997
Polycation‐based DNA complexes for tumor‐targeted gene delivery in vivo
R Kircheis, S Schüller, S Brunner, M Ogris, KH Heider, W Zauner, ...
The journal of gene medicine 1 (2), 111-120, 1999
5231999
Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application
R Kircheis, L Wightman, A Schreiber, B Robitza, V Rössler, M Kursa, ...
Gene therapy 8 (1), 28-40, 2001
4852001
Novel shielded transferrin− polyethylene glycol− polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer
M Kursa, GF Walker, V Roessler, M Ogris, W Roedl, R Kircheis, E Wagner
Bioconjugate chemistry 14 (1), 222-231, 2003
4292003
Tumor-targeted gene therapy: strategies for the preparation of ligand–polyethylene glycol–polyethylenimine/DNA complexes
M Ogris, G Walker, T Blessing, R Kircheis, M Wolschek, E Wagner
Journal of Controlled Release 91 (1-2), 173-181, 2003
3982003
Different strategies for formation of pegylated EGF-conjugated PEI/DNA complexes for targeted gene delivery
T Blessing, M Kursa, R Holzhauser, R Kircheis, E Wagner
Bioconjugate chemistry 12 (4), 529-537, 2001
3512001
Cancer immunotherapy
M Schuster, A Nechansky, R Kircheis
Biotechnology Journal: Healthcare Nutrition Technology 1 (2), 138-147, 2006
2822006
Tumor targeting with surface-shielded ligand–polycation DNA complexes
R Kircheis, T Blessing, S Brunner, L Wightman, E Wagner
Journal of controlled release 72 (1-3), 165-170, 2001
2332001
NF-κB pathway as a potential target for treatment of critical stage COVID-19 patients
R Kircheis, E Haasbach, D Lueftenegger, WT Heyken, M Ocker, O Planz
Frontiers in immunology 11, 598444, 2020
1842020
Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice
MF Wolschek, C Thallinger, M Kursa, V Rössler, M Allen, C Lichtenberger, ...
Hepatology 36 (5), 1106-1114, 2002
1542002
Tumor-targeted gene delivery of tumor necrosis factor-α induces tumor necrosis and tumor regression without systemic toxicity
R Kircheis, E Ostermann, MF Wolschek, C Lichtenberger, ...
Cancer gene therapy 9 (8), 673-680, 2002
1312002
Increase of proliferation rate and enhancement of antitumor cytotoxicity of expanded human CD3+ CD56+ immunologic effector cells by receptor-mediated transfection with the …
S Finke, B Trojaneck, P Lefterova, M Csipai, E Wagner, R Kircheis, ...
Gene therapy 5 (1), 31-39, 1998
1141998
Polymeric gene delivery: principles and applications
MM Amiji
CRC press, 2004
1082004
Analysis of lysine clipping of a humanized Lewis-Y specific IgG antibody and its relation to Fc-mediated effector function
B Antes, S Amon, A Rizzi, S Wiederkum, M Kainer, O Szolar, M Fido, ...
Journal of chromatography b 852 (1-2), 250-256, 2007
1072007
Targeted nucleic acid delivery into tumors: new avenues for cancer therapy
E Wagner, R Kircheis, GF Walker
Biomedicine & pharmacotherapy 58 (3), 152-161, 2004
992004
Tumor-targeted gene delivery: an attractive strategy to use highly active effector molecules in cancer treatment
R Kircheis, L Wightman, M Kursa, E Ostermann, E Wagner
Gene therapy 9 (11), 731-735, 2002
912002
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