Laura Fachal
Laura Fachal
Wellcome Sanger Institute - Human Genetics
Verified email at - Homepage
Cited by
Cited by
Association analysis identifies 65 new breast cancer risk loci
K Michailidou, S Lindström, J Dennis, J Beesley, S Hui, S Kar, A Lemaçon, ...
Nature 551 (7678), 92-94, 2017
Polygenic risk scores for prediction of breast cancer and breast cancer subtypes
N Mavaddat, K Michailidou, J Dennis, M Lush, L Fachal, A Lee, JP Tyrer, ...
The American Journal of Human Genetics 104 (1), 21-34, 2019
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
FR Schumacher, AA Al Olama, SI Berndt, S Benlloch, M Ahmed, ...
Nature genetics 50 (7), 928-936, 2018
Breast cancer risk genes—association analysis in more than 113,000 women
Breast Cancer Association Consortium
New England Journal of Medicine 384 (5), 428-439, 2021
The OncoArray Consortium: a network for understanding the genetic architecture of common cancers
CI Amos, J Dennis, Z Wang, J Byun, FR Schumacher, SA Gayther, ...
Cancer epidemiology, biomarkers & prevention 26 (1), 126-135, 2017
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer
RL Milne, KB Kuchenbaecker, K Michailidou, J Beesley, S Kar, ...
Nature genetics 49 (12), 1767-1778, 2017
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
DV Conti, BF Darst, LC Moss, EJ Saunders, X Sheng, A Chou, ...
Nature genetics 53 (1), 65-75, 2021
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
L Wu, W Shi, J Long, X Guo, K Michailidou, J Beesley, MK Bolla, XO Shu, ...
Nature genetics 50 (7), 968-978, 2018
Establishment of a Radiogenomics Consortium
C West, BS Rosenstein, J Alsner, D Azria, G Barnett, A Begg, S Bentzen, ...
Int J Radiat Oncol Biol Phys 76 (5), 1295-6, 2010
A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity
GC Barnett, D Thompson, L Fachal, S Kerns, C Talbot, RM Elliott, ...
Radiotherapy and Oncology 111 (2), 178-185, 2014
A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24. 1
L Fachal, A Gomez-Caamano, GC Barnett, P Peleteiro, AM Carballo, ...
Nature genetics 46 (8), 891-894, 2014
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes
L Fachal, H Aschard, J Beesley, DR Barnes, J Allen, S Kar, KA Pooley, ...
Nature genetics 52 (1), 56-73, 2020
Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients
CN Andreassen, BS Rosenstein, SL Kerns, H Ostrer, D De Ruysscher, ...
Radiotherapy and Oncology 121 (3), 431-439, 2016
Radiogenomics: radiobiology enters the era of big data and team science
BS Rosenstein, CM West, SM Bentzen, J Alsner, CN Andreassen, D Azria, ...
International journal of radiation oncology, biology, physics 89 (4), 709-713, 2014
From candidate gene studies to GWAS and post-GWAS analyses in breast cancer
L Fachal, AM Dunning
Current opinion in genetics & development 30, 32-41, 2015
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants
T Dadaev, EJ Saunders, PJ Newcombe, E Anokian, DA Leongamornlert, ...
Nature communications 9 (1), 2256, 2018
Genome-wide association study identifies a region on chromosome 11q14. 3 associated with late rectal bleeding following radiation therapy for prostate cancer
SL Kerns, RG Stock, NN Stone, L Rath, A Vega, L Fachal, ...
Radiotherapy and Oncology 107 (3), 372-376, 2013
Meta-analysis of genome wide association studies identifies genetic markers of late toxicity following radiotherapy for prostate cancer
SL Kerns, L Dorling, L Fachal, S Bentzen, PDP Pharoah, DR Barnes, ...
EBioMedicine 10, 150-163, 2016
Radiogenomics consortium genome-wide association study meta-analysis of late toxicity after prostate cancer radiotherapy
SL Kerns, L Fachal, L Dorling, GC Barnett, A Baran, DR Peterson, ...
JNCI: Journal of the National Cancer Institute 112 (2), 179-190, 2020
Comparison of mRNA splicing assay protocols across multiple laboratories: recommendations for best practice in standardized clinical testing
PJ Whiley, M De La Hoya, M Thomassen, A Becker, R Brandão, ...
Clinical chemistry 60 (2), 341-352, 2014
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