Laura Fachal

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Angel CarracedoGrupo de Medicina Xenomica. Instituto Ciencias Forenses. Universidad de Santiago de CompostelaVerified email at usc.es
Ana BlancoFundación Ramón DomínguezVerified email at usc.es
Alison M DunningCentre for Cancer Genetic Epidemiology, Dept of Oncology, University of CambridgeVerified email at medschl.cam.ac.uk
Antonio Salas (orcid: 0000-0002-2336...Full Professor USC (ROR 030eybx10) and IDIS (ROR 05n7xcf53); Galicia - SpainVerified email at usc.es
Catharine WestProfessor of Radiation Biology, University of ManchesterVerified email at manchester.ac.uk
Manuel Sánchez GarcíaMedical PhysicistVerified email at sergas.es
Leila DorlingCentre for Cancer Genetic Epidemiology, University of CambridgeVerified email at medschl.cam.ac.uk
Jonathan BeesleyQIMR BerghoferVerified email at qimrberghofer.edu.au
Matthew R SydesMRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University CollegeVerified email at ucl.ac.uk
Amanda SpurdleQIMR Berghofer Medical Research InstituteVerified email at qimr.edu.au
Alberto Gómez-CarballaGenetics, Vaccines, Infectious Diseases and Pediatrics research group (GENVIP)Verified email at sergas.es
Sara Gutiérrez-EnríquezVall d'Hebron Institute of OncologyVerified email at vhio.net
Kyriaki MichailidouBiostatistics Unit, The Cyprus Institute of Neurology and GeneticsVerified email at cing.ac.cy
Douglas EastonProfessor of Genetic Epidemiology, University of CambridgeVerified email at medschl.cam.ac.uk
Georgia Chenevix-TrenchQueensland Institute of Medical ResearchVerified email at qimr.edu.au
Federico Martinon-TorresHead of Pediatrics, Translational Pediatrics and Infectious Diseases, Hospital Clínico UniversitarioVerified email at usc.es
Daniel R BarnesCentre for Cancer Genetic Epidemiology, University of CambridgeVerified email at medschl.cam.ac.uk
Prof. Antonis C. AntoniouProfessor of Cancer Risk Prediction, University of CambridgeVerified email at medschl.cam.ac.uk
Mahdi Moradi MarjanehImperial College LondonVerified email at imperial.ac.uk
Juliet FrenchQIMR Berghofer Medical Research InstituteVerified email at qimrberghofer.edu.au

Laura Fachal

Wellcome Sanger Institute - Human Genetics

Verified email at sanger.ac.uk - Homepage

Genetic Epidemiology


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Association analysis identifies 65 new breast cancer risk loci K Michailidou, S Lindström, J Dennis, J Beesley, S Hui, S Kar, A Lemaçon, ... Nature 551 (7678), 92-94, 2017	1231	2017
Polygenic risk scores for prediction of breast cancer and breast cancer subtypes N Mavaddat, K Michailidou, J Dennis, M Lush, L Fachal, A Lee, JP Tyrer, ... The American Journal of Human Genetics 104 (1), 21-34, 2019	827	2019
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci FR Schumacher, AA Al Olama, SI Berndt, S Benlloch, M Ahmed, ... Nature genetics 50 (7), 928-936, 2018	706	2018
Breast cancer risk genes—association analysis in more than 113,000 women Breast Cancer Association Consortium New England Journal of Medicine 384 (5), 428-439, 2021	536	2021
The OncoArray Consortium: a network for understanding the genetic architecture of common cancers CI Amos, J Dennis, Z Wang, J Byun, FR Schumacher, SA Gayther, ... Cancer epidemiology, biomarkers & prevention 26 (1), 126-135, 2017	347	2017
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer RL Milne, KB Kuchenbaecker, K Michailidou, J Beesley, S Kar, ... Nature genetics 49 (12), 1767-1778, 2017	322	2017
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction DV Conti, BF Darst, LC Moss, EJ Saunders, X Sheng, A Chou, ... Nature genetics 53 (1), 65-75, 2021	272	2021
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer L Wu, W Shi, J Long, X Guo, K Michailidou, J Beesley, MK Bolla, XO Shu, ... Nature genetics 50 (7), 968-978, 2018	198	2018
Establishment of a Radiogenomics Consortium C West, BS Rosenstein, J Alsner, D Azria, G Barnett, A Begg, S Bentzen, ... Int J Radiat Oncol Biol Phys 76 (5), 1295-6, 2010	189	2010
A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity GC Barnett, D Thompson, L Fachal, S Kerns, C Talbot, RM Elliott, ... Radiotherapy and Oncology 111 (2), 178-185, 2014	178	2014
A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24. 1 L Fachal, A Gomez-Caamano, GC Barnett, P Peleteiro, AM Carballo, ... Nature genetics 46 (8), 891-894, 2014	163	2014
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes L Fachal, H Aschard, J Beesley, DR Barnes, J Allen, S Kar, KA Pooley, ... Nature genetics 52 (1), 56-73, 2020	143	2020
Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients CN Andreassen, BS Rosenstein, SL Kerns, H Ostrer, D De Ruysscher, ... Radiotherapy and Oncology 121 (3), 431-439, 2016	122	2016
Radiogenomics: radiobiology enters the era of big data and team science BS Rosenstein, CM West, SM Bentzen, J Alsner, CN Andreassen, D Azria, ... International journal of radiation oncology, biology, physics 89 (4), 709-713, 2014	120	2014
From candidate gene studies to GWAS and post-GWAS analyses in breast cancer L Fachal, AM Dunning Current opinion in genetics & development 30, 32-41, 2015	101	2015
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants T Dadaev, EJ Saunders, PJ Newcombe, E Anokian, DA Leongamornlert, ... Nature communications 9 (1), 2256, 2018	99	2018
Genome-wide association study identifies a region on chromosome 11q14. 3 associated with late rectal bleeding following radiation therapy for prostate cancer SL Kerns, RG Stock, NN Stone, L Rath, A Vega, L Fachal, ... Radiotherapy and Oncology 107 (3), 372-376, 2013	94	2013
Meta-analysis of genome wide association studies identifies genetic markers of late toxicity following radiotherapy for prostate cancer SL Kerns, L Dorling, L Fachal, S Bentzen, PDP Pharoah, DR Barnes, ... EBioMedicine 10, 150-163, 2016	88	2016
Radiogenomics consortium genome-wide association study meta-analysis of late toxicity after prostate cancer radiotherapy SL Kerns, L Fachal, L Dorling, GC Barnett, A Baran, DR Peterson, ... JNCI: Journal of the National Cancer Institute 112 (2), 179-190, 2020	84	2020
Comparison of mRNA splicing assay protocols across multiple laboratories: recommendations for best practice in standardized clinical testing PJ Whiley, M De La Hoya, M Thomassen, A Becker, R Brandão, ... Clinical chemistry 60 (2), 341-352, 2014	81	2014

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