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Sebastian Schäfer
Sebastian Schäfer
Duke-NUS Medical School
Verified email at duke-nus.edu.sg
Title
Cited by
Cited by
Year
Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy
JT Hinson, A Chopra, N Nafissi, WJ Polacheck, CC Benson, S Swist, ...
Science 349 (6251), 982-986, 2015
6172015
RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing
W Guo*, S Schafer*, ML Greaser, MH Radke, M Liss, T Govindarajan, ...
Nature Medicine, 2012
5782012
IL-11 is a crucial determinant of cardiovascular fibrosis
S Schafer, S Viswanathan, AA Widjaja, WW Lim, A Moreno-Moral, ...
Nature 552 (7683), 110, 2017
5102017
Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease
AM Roberts, JS Ware, DS Herman, S Schafer, J Baksi, AG Bick, ...
Science translational medicine 7 (270), 270ra6-270ra6, 2015
4422015
The translational landscape of the human heart
S van Heesch, F Witte, V Schneider-Lunitz, JF Schulz, E Adami, AB Faber, ...
Cell 178 (1), 242-260. e29, 2019
4372019
Titin-truncating variants affect heart function in disease cohorts and the general population.
S Schafer, A De Marvao, E Adami, LR Fiedler, B Ng, E Khin, OJ Rackham, ...
Nature genetics 49 (1), 46-53, 2017
2872017
Engineered cell homing
D Sarkar, JA Spencer, JA Phillips, W Zhao, S Schafer, DP Spelke, ...
Blood 118 (25), e184-e191, 2011
2422011
Cell-surface sensors for real-time probing of cellular environments
W Zhao, S Schafer, J Choi, YJ Yamanaka, ML Lombardi, S Bose, ...
Nature nanotechnology 6 (8), 524-531, 2011
2122011
IL-11 is a therapeutic target in idiopathic pulmonary fibrosis
S Cook, B Ng, J Dong, S Viswanathan, G DAgostino, A Widjaja, WW Lim, ...
BioRxiv, 336537, 2018
210*2018
RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing
H Maatz, M Jens, M Liss, S Schafer, M Heinig, M Kirchner, E Adami, ...
The Journal of clinical investigation 124 (8), 3419-3430, 2014
2102014
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
B Ng, J Dong, G D’Agostino, S Viswanathan, AA Widjaja, WW Lim, ...
Science translational medicine 11 (511), eaaw1237, 2019
2072019
Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis
AA Widjaja, BK Singh, E Adami, S Viswanathan, J Dong, GA D’Agostino, ...
Gastroenterology 157 (3), 777-792. e14, 2019
2042019
Fine Mapping of the 1p36 Deletion Syndrome Identifies Mutation of PRDM16 as a Cause of Cardiomyopathy
AK Arndt, S Schafer, JD Drenckhahn, MK Sabeh, ER Plovie, A Caliebe, ...
The American Journal of Human Genetics, 2013
2002013
Recessive TTN truncating mutations define novel forms of core myopathy with heart disease
C Chauveau, CG Bonnemann, C Julien, AL Kho, H Marks, B Talim, ...
Human molecular genetics 23 (4), 980-991, 2014
1802014
Alternative Splicing Signatures in RNA‐seq Data: Percent Spliced in (PSI)
S Schafer, K Miao, CC Benson, M Heinig, SA Cook, N Hubner
Current Protocols in Human Genetics, 11.16. 1-11.16. 14, 2015
1572015
Characterising the loss-of-function impact of 5'untranslated region variants in whole genome sequence data from 15,708 individuals
N Whiffin, KJ Karczewski, X Zhang, S Chothani, MJ Smith, DG Evans, ...
bioRxiv, 543504, 2019
133*2019
Quantitative and Qualitative Proteome Characteristics Extracted from In-Depth Integrated Genomics and Proteomics Analysis
TY Low, S van Heesch, H van den Toorn, P Giansanti, A Cristobal, ...
Cell reports 5 (5), 1469-1478, 2013
1302013
Characterising the loss-of-function impact of 5’untranslated region variants in 15,708 individuals
N Whiffin, KJ Karczewski, X Zhang, S Chothani, MJ Smith, DG Evans, ...
Nature communications 11 (1), 2523, 2020
1282020
52 genetic loci influencing myocardial mass
P Van der Harst, J van Setten, N Verweij, G Vogler, L Franke, ...
Journal of the American College of Cardiology 68 (13), 1435-1448, 2016
1232016
Hiding in Plain Sight: Interleukin-11 Emerges as a Master Regulator of Fibrosis, Tissue Integrity, and Stromal Inflammation
SA Cook, S Schafer
Annual Review of Medicine 71, 263-276, 2020
1182020
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