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Laura Ciapponi
Laura Ciapponi
Associate Professor of Genetics, Dept Biology and Biotechnologies, Sapienza University of Rome
Verified email at uniroma1.it - Homepage
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Year
Two distinct and independent sites on IL‐6 trigger gp 130 dimer formation and signalling.
G Paonessa, R Graziani, A De Serio, R Savino, L Ciapponi, A Lahm, ...
The EMBO journal 14 (9), 1942-1951, 1995
3391995
Rational design of a receptor super‐antagonist of human interleukin‐6.
R Savino, L Ciapponi, A Lahm, A Demartis, A Cabibbo, C Toniatti, ...
The EMBO Journal 13 (24), 5863-5870, 1994
1691994
Generation of interleukin‐6 receptor antagonists by molecular‐modeling guided mutagenesis of residues important for gp130 activation.
R Savino, A Lahm, AL Salvati, L Ciapponi, E Sporeno, S Altamura, ...
The EMBO journal 13 (6), 1357-1367, 1994
1671994
The Drosophila Mre11/Rad50 complex is required to prevent both telomeric fusion and chromosome breakage
L Ciapponi, G Cenci, J Ducau, C Flores, D Johnson-Schlitz, MM Gorski, ...
Current biology 14 (15), 1360-1366, 2004
1492004
Human interleukin-6 receptor super-antagonists with high potency and wide spectrum on multiple myeloma cells
E Sporeno, R Savino, L Ciapponi, G Paonessa, A Cabibbo, A Lahm, ...
1341996
The mechanism of telomere protection: a comparison between Drosophila and humans
G Cenci, L Ciapponi, M Gatti
Chromosoma 114, 135-145, 2005
1222005
Drosophila Fos mediates ERK and JNK signals via distinct phosphorylation sites
L Ciapponi, DB Jackson, M Mlodzik, D Bohmann
Genes & development 15 (12), 1540-1553, 2001
1032001
Identification of Drosophila Mitotic Genes by Combining Co-Expression Analysis and RNA Interference
MP Somma, F Ceprani, E Bucciarelli, V Naim, V De Arcangelis, ...
PLoS genetics 4 (7), e1000126, 2008
1002008
Terminin: A protein complex that mediates epigenetic maintenance of Drosophila telomeres
GD Raffa, L Ciapponi, G Cenci, M Gatti
Nucleus 2 (5), 383-391, 2011
882011
Verrocchio, a Drosophila OB fold-containing protein, is a component of the terminin telomere-capping complex
GD Raffa, D Raimondo, C Sorino, S Cugusi, G Cenci, S Cacchione, ...
Genes & development 24 (15), 1596-1601, 2010
822010
The Drosophila modigliani (moi) gene encodes a HOAP-interacting protein required for telomere protection
GD Raffa, G Siriaco, S Cugusi, L Ciapponi, G Cenci, E Wojcik, M Gatti
Proceedings of the National Academy of Sciences 106 (7), 2271-2276, 2009
812009
Non-canonical Hedgehog/AMPK-mediated control of polyamine metabolism supports neuronal and medulloblastoma cell growth
D D’Amico, L Antonucci, L Di Magno, S Coni, G Sdruscia, A Macone, ...
Developmental cell 35 (1), 21-35, 2015
782015
The Drosophila Nbs protein functions in multiple pathways for the maintenance of genome stability
L Ciapponi, G Cenci, M Gatti
Genetics 173 (3), 1447-1454, 2006
602006
Induction of interleukin-6 (IL-6) autoantibodies through vaccination with an engineered IL-6 receptor antagonist
L Ciapponi, D Maione, A Scoumanne, P Costa, MB Hansen, M Svenson, ...
Nature biotechnology 15 (10), 997-1001, 1997
521997
Unprotected Drosophila melanogaster telomeres activate the spindle assembly checkpoint
M Musaro, L Ciapponi, B Fasulo, M Gatti, G Cenci
Nature genetics 40 (3), 362-366, 2008
492008
Definition of a Composite Binding Site for gp130 in Human Interleukin-6 (∗)
L Ciapponi, R Graziani, G Paonessa, A Lahm, G Ciliberto, R Savino
Journal of Biological Chemistry 270 (52), 31249-31254, 1995
421995
AKTIP/Ft1, a new shelterin-interacting factor required for telomere maintenance
R Burla, M Carcuro, GD Raffa, A Galati, D Raimondo, A Rizzo, M La Torre, ...
PLoS genetics 11 (6), e1005167, 2015
372015
An essential function of AP-1 heterodimers in Drosophila development
L Ciapponi, D Bohmann
Mechanisms of development 115 (1-2), 35-40, 2002
362002
Organization and Evolution of Drosophila Terminin: Similarities and Differences between Drosophila and Human Telomeres
GD Raffa, G Cenci, L Ciapponi, M Gatti
Frontiers in oncology 3, 112, 2013
342013
Cytokine gene expression in intestine of rat during the postnatal developmental period: increased IL-1 expression at weaning
E Mengheri, L Ciapponi, F Vignolini, F Nobili
Life sciences 59 (15), 1227-1236, 1996
291996
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