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Gopuraja Dharmalingam
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A complex secretory program orchestrated by the inflammasome controls paracrine senescence
JC Acosta, A Banito, T Wuestefeld, A Georgilis, P Janich, JP Morton, ...
Nature cell biology 15 (8), 978-990, 2013
19482013
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype
N Herranz, S Gallage, M Mellone, T Wuestefeld, S Klotz, CJ Hanley, ...
Nature cell biology 17 (9), 1205-1217, 2015
6792015
Cardiac glycosides are broad-spectrum senolytics
A Guerrero, N Herranz, B Sun, V Wagner, S Gallage, R Guiho, K Wolter, ...
Nature metabolism 1 (11), 1074-1088, 2019
2502019
Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte
PWS Hill, HG Leitch, CE Requena, Z Sun, R Amouroux, M Roman-Trufero, ...
Nature 555 (7696), 392-396, 2018
2332018
Identification of microRNA-regulated gene networks by expression analysis of target genes
VA Gennarino, G d'Angelo, G Dharmalingam, S Fernandez, G Russolillo, ...
Genome research 22 (6), 1163-1172, 2012
2162012
Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation
S Cuartero, FD Weiss, G Dharmalingam, Y Guo, E Ing-Simmons, ...
Nature immunology 19 (9), 932-941, 2018
1822018
PTBP1-mediated alternative splicing regulates the inflammatory secretome and the pro-tumorigenic effects of senescent cells
A Georgilis, S Klotz, CJ Hanley, N Herranz, B Weirich, B Morancho, ...
Cancer cell 34 (1), 85-102. e9, 2018
1812018
Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B–cell differentiation
I Ferreirˇs-Vidal, T Carroll, B Taylor, A Terry, Z Liang, L Bruno, ...
Blood, The Journal of the American Society of Hematology 121 (10), 1769-1782, 2013
1352013
The aurora B kinase and the polycomb protein ring1B combine to regulate active promoters in quiescent lymphocytes
A Frangini, M Sj÷berg, M Roman-Trufero, G Dharmalingam, V Haberle, ...
Molecular cell 51 (5), 647-661, 2013
1262013
Transcriptional gene network inference from a massive dataset elucidates transcriptome organization and gene function
V Belcastro, V Siciliano, F Gregoretti, P Mithbaokar, G Dharmalingam, ...
Nucleic acids research 39 (20), 8677-8688, 2011
1232011
Continuous histone replacement by Hira is essential for normal transcriptional regulation and de novo DNA methylation during mouse oogenesis
B Nashun, PWS Hill, SA Smallwood, G Dharmalingam, R Amouroux, ...
Molecular cell 60 (4), 611-625, 2015
1162015
microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells
A Marcais, R Blevins, J Graumann, A Feytout, G Dharmalingam, T Carroll, ...
Journal of Experimental Medicine 211 (11), 2281-2295, 2014
682014
HOCTAR database: a unique resource for microRNA target prediction
VA Gennarino, M Sardiello, M Mutarelli, G Dharmalingam, V Maselli, ...
Gene 480 (1-2), 51-58, 2011
632011
Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence
M Aarts, A Georgilis, M Beniazza, P Beolchi, A Banito, T Carroll, M Kulisic, ...
Genes & Development 31 (20), 2085-2098, 2017
492017
The ADAMTS18 gene is responsible for autosomal recessive early onset severe retinal dystrophy
I Peluso, I Conte, F Testa, G Dharmalingam, M Pizzo, RWJ Collin, ...
Orphanet journal of rare diseases 8, 1-8, 2013
472013
Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK4a regulation
N Martin, N Popov, F Aguilo, A O'loghlen, S Raguz, AP Snijders, ...
The EMBO journal 32 (7), 982-995, 2013
472013
Cohesin-dependence of neuronal gene expression relates to chromatin loop length
L Calderon, FD Weiss, JA Beagan, MS Oliveira, R Georgieva, YF Wang, ...
Elife 11, e76539, 2022
442022
Initiation and maintenance of pluripotency gene expression in the absence of cohesin
T Lavagnolli, P Gupta, E H÷rmanseder, H Mira-Bontenbal, ...
Genes & Development 29 (1), 23-38, 2015
342015
MicroRNAs of the miR-290–295 family maintain bivalency in mouse embryonic stem cells
B Graham, A Marcais, G Dharmalingam, T Carroll, C Kanellopoulou, ...
Stem Cell Reports 6 (5), 635-642, 2016
292016
A community-based resource for automatic exome variant-calling and annotation in Mendelian disorders
M Mutarelli, VS Marwah, R Rispoli, D Carrella, G Dharmalingam, G Oliva, ...
BMC genomics 15, 1-7, 2014
282014
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Articles 1–20