H Eric Xu
H Eric Xu
Professor of Structure Biology, Van Andel Research Institute, VARI-SIMM Center, Shanghai Institute
Verified email at vai.org - Homepage
TitleCited byYear
A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport
WR Oliver, JL Shenk, MR Snaith, CS Russell, KD Plunket, NL Bodkin, ...
Proceedings of the national academy of sciences 98 (9), 5306-5311, 2001
12822001
Molecular recognition of fatty acids by peroxisome proliferator–activated receptors
HE Xu, MH Lambert, VG Montana, DJ Parks, SG Blanchard, PJ Brown, ...
Molecular cell 3 (3), 397-403, 1999
12171999
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition
RK Bledsoe, VG Montana, TB Stanley, CJ Delves, CJ Apolito, DD McKee, ...
Cell 110 (1), 93-105, 2002
7592002
Asymmetry in the PPARγ/RXRα crystal structure reveals the molecular basis of heterodimerization among nuclear receptors
RT Gampe Jr, VG Montana, MH Lambert, AB Miller, RK Bledsoe, ...
Molecular cell 5 (3), 545-555, 2000
6182000
Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα
HE Xu, TB Stanley, VG Montana, MH Lambert, BG Shearer, JE Cobb, ...
Nature 415 (6873), 813, 2002
6112002
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors
HE Xu, MH Lambert, VG Montana, KD Plunket, LB Moore, JL Collins, ...
Proceedings of the National Academy of Sciences 98 (24), 13919-13924, 2001
5562001
A gate–latch–lock mechanism for hormone signalling by abscisic acid receptors
K Melcher, LM Ng, XE Zhou, FF Soon, Y Xu, KM Suino-Powell, SY Park, ...
Nature 462 (7273), 602, 2009
5142009
Structural features for functional selectivity at serotonin receptors
D Wacker, C Wang, V Katritch, GW Han, XP Huang, E Vardy, JD McCorvy, ...
Science 340 (6132), 615-619, 2013
4802013
Peroxisome proliferator-activated receptors: from genes to physiology.
SA Kliewer, HE Xu, MH Lambert, TM Willson
Recent progress in hormone research 56, 239-263, 2001
4792001
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Y Kang, XE Zhou, X Gao, Y He, W Liu, A Ishchenko, A Barty, TA White, ...
Nature 523 (7562), 561, 2015
4352015
Identification of a physiologically relevant endogenous ligand for PPARα in liver
MV Chakravarthy, IJ Lodhi, L Yin, RRV Malapaka, HE Xu, J Turk, ...
Cell 138 (3), 476-488, 2009
4292009
Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity
JR Huh, MWL Leung, P Huang, DA Ryan, MR Krout, RRV Malapaka, ...
Nature 472 (7344), 486, 2011
4092011
Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans
DL Motola, CL Cummins, V Rottiers, KK Sharma, T Li, Y Li, ...
Cell 124 (6), 1209-1223, 2006
4022006
DWARF 53 acts as a repressor of strigolactone signalling in rice
L Jiang, X Liu, G Xiong, H Liu, F Chen, L Wang, X Meng, G Liu, H Yu, ...
Nature 504 (7480), 401, 2013
3812013
FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis
S Kir, SA Beddow, VT Samuel, P Miller, SF Previs, K Suino-Powell, HE Xu, ...
Science 331 (6024), 1621-1624, 2011
3722011
Structural basis for molecular recognition at serotonin receptors
C Wang, Y Jiang, J Ma, H Wu, D Wacker, V Katritch, GW Han, W Liu, ...
Science 340 (6132), 610-614, 2013
3692013
Novel selective small molecule agonists for peroxisome proliferator-activated receptor δ (PPARδ)—synthesis and biological activity
ML Sznaidman, CD Haffner, PR Maloney, A Fivush, E Chao, D Goreham, ...
Bioorganic & medicinal chemistry letters 13 (9), 1517-1521, 2003
3562003
Structural basis for molecular recognition of folic acid by folate receptors
C Chen, J Ke, XE Zhou, W Yi, JS Brunzelle, J Li, EL Yong, HE Xu, ...
Nature 500 (7463), 486, 2013
3342013
Crystal structure of the human Pax6 paired domain–DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding
HE Xu, MA Rould, W Xu, JA Epstein, RL Maas, CO Pabo
Genes & development 13 (10), 1263-1275, 1999
2741999
Molecular mimicry regulates ABA signaling by SnRK2 kinases and PP2C phosphatases
FF Soon, LM Ng, XE Zhou, GM West, A Kovach, MH Tan, ...
Science 335 (6064), 85, 2012
2702012
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Articles 1–20