| Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation CJ Tape, S Ling, M Dimitriadi, K McMahon, JD Worboys, HS Leong, ... Cell 165 (4), 2016 | 453 | 2016 |
| Thiol isomerases negatively regulate the cellular shedding activity of ADAM17 SH Willems, CJ Tape, PL Stanley, NA Taylor, IG Mills, DE Neal, ... Biochemical Journal 428 (3), 439-450, 2010 | 213 | 2010 |
| Cross-domain inhibition of TACE ectodomain CJ Tape, SH Willems, SL Dombernowsky, PL Stanley, M Fogarasi, ... Proceedings of the National Academy of Sciences 108 (14), 5578-5583, 2011 | 147 | 2011 |
| Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis R Natrajan, H Sailem, F Mardakheh, MA Garcia, CJ Tape, M Dowsett, ... PLoS Medicine, 2016 | 143 | 2016 |
| Myosin II reactivation and cytoskeletal remodeling as a hallmark and a vulnerability in melanoma therapy resistance JL Orgaz, E Crosas-Molist, A Sadok, A Perdrix-Rosell, O Maiques, ... Cancer Cell 37 (1), 85-103. e9, 2020 | 138 | 2020 |
| Cell-type-specific signaling networks in heterocellular organoids X Qin, J Sufi, P Vlckova, P Kyriakidou, SE Acton, VSW Li, M Nitz, CJ Tape Nature methods 17 (3), 335-342, 2020 | 125 | 2020 |
| Anti-tumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivo FM Richards, CJ Tape, DI Jodrell, G Murphy PloS one 7 (7), e40597, 2012 | 100 | 2012 |
| Crosstalk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination M Montagner, R Bhome, S Hooper, P Chakravarty, X Qin, J Sufi, ... Nature Cell Biology 22 (3), 289-296, 2020 | 99 | 2020 |
| Fibroblastic reticular cells control conduit matrix deposition during lymph node expansion VG Martinez, V Pankova, L Krasny, T Singh, S Makris, IJ White, ... Cell reports 29 (9), 2810-2822. e5, 2019 | 93 | 2019 |
| Reproducible Automated Phosphopeptide Enrichment Using Magnetic TiO2 and Ti-IMAC CJ Tape, JD Worboys, J Sinclair, R Gourlay, J Vogt, KM McMahon, ... Analytical chemistry 86 (20), 10296-10302, 2014 | 89 | 2014 |
| Targeting ADAM-17 with an inhibitory monoclonal antibody has antitumour effects in triple-negative breast cancer cells F Caiazza, PM McGowan, M Mullooly, A Murray, N Synnott, N O'Donovan, ... British Journal of Cancer 112 (12), 1895-1903, 2015 | 76 | 2015 |
| Targeting the sheddase activity of ADAM17 by an anti-ADAM17 antibody D1 (A12) inhibits head and neck squamous cell carcinoma cell proliferation and motility via blockage of … Y Huang, N Benaich, C Tape, HF Kwok, G Murphy International journal of biological sciences 10 (7), 702, 2014 | 54 | 2014 |
| An oncogenic phenoscape of colonic stem cell polarization X Qin, FC Rodriguez, J Sufi, P Vlckova, J Claus, CJ Tape Cell 186 (25), 5554-5568. e18, 2023 | 50 | 2023 |
| Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2) S Santamaria, K Yamamoto, K Botkjaer, C Tape, MR Dyson, J McCafferty, ... Biochemical Journal 471 (3), 391-401, 2015 | 49 | 2015 |
| Development of a ‘mouse and human cross-reactive’affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy HF Kwok, KA Botkjaer, CJ Tape, Y Huang, J McCafferty, G Murphy Protein Engineering, Design & Selection 27 (6), 179-190, 2014 | 40 | 2014 |
| An Artemis polymorphic variant reduces Artemis activity and confers cellular radiosensitivity L Woodbine, S Grigoriadou, AA Goodarzi, E Riballo, C Tape, AW Oliver, ... DNA repair 9 (9), 1003-1010, 2010 | 40 | 2010 |
| Cell-specific labeling enzymes for analysis of cell–cell communication in continuous co-culture CJ Tape, IC Norrie, JD Worboys, L Lim, DA Lauffenburger, C Jørgensen Molecular & Cellular Proteomics 13 (7), 1866-1876, 2014 | 39 | 2014 |
| Multiplexed single-cell analysis of organoid signaling networks J Sufi, X Qin, FC Rodriguez, YJ Bu, P Vlckova, MR Zapatero, M Nitz, ... Nature protocols 16 (10), 4897-4918, 2021 | 38 | 2021 |
| Trellis tree-based analysis reveals stromal regulation of patient-derived organoid drug responses MR Zapatero, A Tong, JW Opzoomer, R O’Sullivan, FC Rodriguez, J Sufi, ... Cell 186 (25), 5606-5619. e24, 2023 | 35 | 2023 |
| Systems biology analysis of heterocellular signaling CJ Tape Trends in biotechnology 34 (8), 627-637, 2016 | 34 | 2016 |
Xiao QinMRC Translational Immune Discovery Unit, MRC WIMM, University of OxfordVerified email at rdm.ox.ac.uk
