Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction KJ Kinghorn, JI Castillo-Quan, F Bartolome, PR Angelova, L Li, S Pope, ... Brain 138 (7), 1801-1816, 2015 | 181 | 2015 |
Lithium promotes longevity through GSK3/NRF2-dependent hormesis JI Castillo-Quan, L Li, KJ Kinghorn, DK Ivanov, LS Tain, C Slack, F Kerr, ... Cell reports 15 (3), 638-650, 2016 | 180 | 2016 |
A Drosophila model of neuronopathic Gaucher disease demonstrates lysosomal-autophagic defects and altered mTOR signalling and is functionally rescued by rapamycin KJ Kinghorn, S Grönke, JI Castillo-Quan, NS Woodling, L Li, E Sirka, ... Journal of Neuroscience 36 (46), 11654-11670, 2016 | 135 | 2016 |
Increased glucose transport into neurons rescues Aβ toxicity in Drosophila T Niccoli, M Cabecinha, A Tillmann, F Kerr, CT Wong, D Cardenes, ... Current Biology 26 (17), 2291-2300, 2016 | 111 | 2016 |
Miro1 marks Parkinson’s disease subset and Miro1 reducer rescues neuron loss in Parkinson’s models CH Hsieh, L Li, R Vanhauwaert, KT Nguyen, MD Davis, G Bu, ZK Wszolek, ... Cell metabolism 30 (6), 1131-1140. e7, 2019 | 105 | 2019 |
A triple drug combination targeting components of the nutrient-sensing network maximizes longevity JI Castillo-Quan, LS Tain, KJ Kinghorn, L Li, S Grönke, Y Hinze, ... Proceedings of the National Academy of Sciences 116 (42), 20817-20819, 2019 | 76 | 2019 |
Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease O Sofola-Adesakin, JI Castillo-Quan, C Rallis, LS Tain, I Bjedov, I Rogers, ... Frontiers in aging neuroscience 6, 190, 2014 | 69 | 2014 |
A mitochondrial membrane-bridging machinery mediates signal transduction of intramitochondrial oxidation L Li, DM Conradson, V Bharat, MJ Kim, CH Hsieh, PS Minhas, ... Nature metabolism 3 (9), 1242-1258, 2021 | 32 | 2021 |
Reply: Glial mitochondropathy in infantile neuroaxonal dystrophy: pathophysiological and therapeutic implications KJ Kinghorn, JI Castillo-Quan, L Li, KP Bhatia, AY Abramov, J Hardy, ... Brain 139 (12), e68-e68, 2016 | | 2016 |
A NOVEL MODEL OF GBA1-ASSOCIATED PARKINSON'S DISEASE IMPLICATES AUTOPHAGY K Kinghorn, S Gronke, JI Castillo-Quan, L Li, N Woodling, E Sirka, ... J Neurol Neurosurg Psychiatry 87 (12), e1-e1, 2016 | | 2016 |