| The orphan receptor GPR55 is a novel cannabinoid receptor E Ryberg, N Larsson, S Sjögren, S Hjorth, NO Hermansson, J Leonova, ... British journal of pharmacology 152 (7), 1092-1101, 2007 | 1895 | 2007 |
| Receptor activity modifying proteins (RAMPs) interact with the VPAC2 receptor and CRF1 receptors and modulate their function D Wootten, H Lindmark, M Kadmiel, H Willcockson, KM Caron, J Barwell, ... British journal of pharmacology 168 (4), 822-834, 2013 | 96 | 2013 |
| Real time visualization of agonist-mediated redistribution and internalization of a green fluorescent protein-tagged form of the thyrotropin-releasing hormone receptor T Drmota, GW Gould, G Milligan Journal of Biological Chemistry 273 (37), 24000-24008, 1998 | 82 | 1998 |
| Discovery of a novel oral glucocorticoid receptor modulator (AZD9567) with improved side effect profile L Ripa, K Edman, M Dearman, G Edenro, R Hendrickx, V Ullah, ... Journal of Medicinal Chemistry 61 (5), 1785-1799, 2018 | 66 | 2018 |
| Agonist-induced internalization of the G protein G11α and thyrotropin-releasing hormone receptors proceed on different time scales T Drmota, J Novotny, GD Kim, KA Eidne, G Milligan, P Svoboda Journal of Biological Chemistry 273 (34), 21699-21707, 1998 | 66 | 1998 |
| Analysis of the C-terminal tail of the rat thyrotropin-releasing hormone receptor-1 in interactions and cointernalization with β-arrestin 1-green fluorescent protein DA Groarke, T Drmota, DS Bahia, NA Evans, S Wilson, G Milligan Molecular Pharmacology 59 (2), 375-385, 2001 | 57 | 2001 |
| Visualization of distinct patterns of subcellular redistribution of the thyrotropin-releasing hormone receptor-1 and Gqα/G11α induced by agonist stimulation T DRMOTA, J NOVOTNY, GW GOULD, P SVOBODA, G MILLIGAN Biochemical Journal 340 (2), 529-538, 1999 | 57 | 1999 |
| Biochemistry of transmembrane signaling mediated by trimeric G proteins P Svoboda, J Teisinger, J Novotny, L Bourova, T Drmota, L Hejnova, ... Physiological research 53, S141-152, 2004 | 52 | 2004 |
| Screening assays for cannabinoid-ligand-type modulators of GPR55 T Drmota, P Greasley, T Groblewski US Patent App. 10/545,851, 2006 | 42 | 2006 |
| Discovery of AZD6642, an inhibitor of 5-lipoxygenase activating protein (FLAP) for the treatment of inflammatory diseases M Lemurell, J Ulander, S Winiwarter, A Dahlen, O Davidsson, ... Journal of Medicinal Chemistry 58 (2), 897-911, 2015 | 39 | 2015 |
| Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats C Bengtsson, S Blaho, DB Saitton, K Brickmann, J Broddefalk, ... Bioorganic & medicinal chemistry 19 (10), 3039-3053, 2011 | 36 | 2011 |
| Inhibition of AMP deaminase activity does not improve glucose control in rodent models of insulin resistance or diabetes T Admyre, L Amrot-Fors, M Andersson, M Bauer, M Bjursell, T Drmota, ... Chemistry & biology 21 (11), 1486-1496, 2014 | 29 | 2014 |
| Kinetic analysis of the internalization and recycling of [3H] TRH and C-terminal truncations of the long isoform of the rat thyrotropin-releasing hormone receptor-1 T DRMOTA, G MILLIGAN Biochemical Journal 346 (3), 711-718, 2000 | 28 | 2000 |
| Molecular cloning, mutations and effects of NK1 receptor antagonists reveal the human-like pharmacology of gerbil NK1 receptors S Engberg, I Ahlstedt, A Leffler, E Lindström, E Kristensson, A Svensson, ... Biochemical pharmacology 73 (2), 259-269, 2007 | 23 | 2007 |
| Functional analysis of a human A1 adenosine receptor/green fluorescent protein/Gi1α fusion protein following stable expression in CHO cells N Bevan, T Palmer, T Drmota, A Wise, J Coote, G Milligan, S Rees FEBS letters 462 (1-2), 61-65, 1999 | 22 | 1999 |
| Senktide-induced gerbil foot tapping behaviour is blocked by selective tachykinin NK1 and NK3 receptor antagonists M Sundqvist, E Kristensson, R Adolfsson, A Leffler, I Ahlstedt, S Engberg, ... European journal of pharmacology 577 (1-3), 78-86, 2007 | 13 | 2007 |
| Adenosine is not a direct GHSR agonist–artificial cross‐talk between GHSR and adenosine receptor pathways NO Hermansson, DGA Morgan, T Drmota, N Larsson Acta physiologica 190 (1), 77-86, 2007 | 12 | 2007 |
| The discovery of a selective and potent A2a agonist with extended lung retention ABM Åstrand, E Lamm Bergström, H Zhang, L Börjesson, T Söderdahl, ... Pharmacology Research & Perspectives 3 (3), e00134, 2015 | 10 | 2015 |
| AstraZeneca T Drmota WO2004074844, 2004 | 10 | 2004 |
| Occurrence and pharmacological characterization of four human tachykinin NK2 receptor variants I Ahlstedt, S Engberg, J Smith, C Perrey, A Moody, J Morten, ... Biochemical pharmacology 76 (4), 476-481, 2008 | 9 | 2008 |
